human herpesvirus-8
Patterns of human herpesvirus-8 oral shedding among diverse cohorts of human herpesvirus-8 seropositive persons
... Human herpesvirus-8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), establishes life- long latent infection, punctuated with periods of lytic replication at mucosal ...
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Intracellular Localization Map of Human Herpesvirus 8 Proteins
... Human herpesvirus 8 (HHV-8) is the etiological agent of Kaposi’s sarcoma. We present a localization map of 85 HHV-8-encoded proteins in mammalian cells. Viral open reading frames were ...
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Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Replication and Transcription Activator Regulates Viral and Cellular Genes via Interferon-Stimulated Response Elements
... sarcoma-associated herpesvirus (also called human herpesvirus 8 [HHV-8]) replication and tran- scription activator (RTA) is apparently necessary and sufficient for the switch from viral ...
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Pregnancy and Human Herpesvirus 8 Reactivation in Human Immunodeficiency Virus Type 1 Infected Women
... Human herpesvirus 8 (HHV-8) is associated with Kaposi’s sarcoma (KS), primary effusion lymphoma, and the plasma cell variant of Castleman’s ...
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K-bZIP of Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 (KSHV/HHV-8) Binds KSHV/HHV-8 Rta and Represses Rta-Mediated Transactivation
... sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) gene expression bears resemblance to that of Epstein-Barr virus (EBV), but with interesting ...
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New approaches to the treatment of human herpesvirus 8-associated disease.
... Human herpesvirus 8 (HHV-8, also known as Kaposi sarcoma-associated herpesvirus or KSHV) is the etiologic agent of Kaposi sarcoma (KS) and primary effusion lymphoma (PEL), as well as ...
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The protease and the assembly protein of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8).
... their human immunodeficiency virus (HIV) ...novel human herpesvirus (KS-associated her- pesvirus [KSHV], also called human herpesvirus 8 [HHV-8]) have been identified in ...
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Multiple human herpesvirus-8 infection
... in human herpesvirus–8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain ...for human immunodeficiency virus type 1, 21 (88%) were ...
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Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Replication and Transcription Factor Activates the K9 (vIRF) Gene through Two Distinct cis Elements by a Non-DNA-Binding Mechanism
... sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8 (HHV8), is found in Kaposi’s sarcoma ...another human B-cell-tropic her- ...
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Seroprevalence of Human herpesvirus 8 (HHV-8) and incidence of Kaposi's sarcoma in Iran
... of human herpesvirus 8 (HHV-8) infection mostly varies in various geographical areas and reflects the local incidence of classic and endemic KS, being widespread in sub- Saharan Africa and ...
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Investigation of the Multimerization Region of the Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Protein K-bZIP: the Proposed Leucine Zipper Region Encodes a Multimerization Domain with an Unusual Structure
... The K8 gene of Kaposi’s sarcoma-associated herpesvirus (human herpesvirus 8) shares many functional similarities with the BZLF1 gene of Epstein-Barr virus. The protein products of K8 and ...
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Three-Dimensional Structure of the Human Herpesvirus 8 Capsid
... Human herpesvirus 8 (HHV-8), also known as Kaposi’s sar- coma (KS)-associated herpesvirus, has been implicated in all forms of KS, in primary effusion lymphoma (PEL), and in ...
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Serodiagnosis of Human Herpesvirus 8 in Women with Breast Cancer
... Human herpesvirus 8 (HHV-8) is a common virus in the Mediterranean region. It has been linked to a number of malignancies, and it is believed to be the causative agent in certain cases. The ...
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Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma
... with human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) that are not fully transformed but are instead driven to excess proliferation by inflammatory and angiogenic ...
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Carboxy Terminus of Human Herpesvirus 8 Latency-Associated Nuclear Antigen Mediates Dimerization, Transcriptional Repression, and Targeting to Nuclear Bodies
... Human herpesvirus 8 (HHV-8; also known as Kaposi’s sarcoma-associated herpesvirus) is the causative agent of Kaposi’s sarcoma and certain B-cell ...
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Activation of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Lytic Replication by Human Cytomegalovirus
... Antibody detection of viral proteins. For the immunofluorescence assay (IFA) detection of KSHV and HCMV, proteins in HF were grown on Lab-Tek Cham- ber slides (Nalge Nunc International), fixed with 4% paraformaldehyde ...
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Human herpesvirus 8 and new pathological associations
... This study identifies the oral mucosa as another site of HHV-8 infection in people who are HIV-infected. Factors that could lead to false-negative results after PCR amplification for HHV-8 DNA fi'om fixed ...
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Lipid Rafts of Primary Endothelial Cells Are Essential for Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8-Induced Phosphatidylinositol 3-Kinase and RhoA-GTPases Critical for Microtubule Dynamics and Nuclear Delivery of Viral DNA but Dispensable for Binding and Entry
... to 8 h, treated with or without 5 mM M  CD for 1 h, and infected with 10 MOI of KSHV for the indicated time ...to 8 h, treated with M  CD for 1 h or untreated, and infected for 30 ...to 8 were ...
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Human herpesvirus 8 – A novel human pathogen
... Another tactic to alter the cell-mediated response to HHV- 8 infection is to make sure this response does not occur upon infection. HHV-8 creates a microenvironment where by there is preferential ...
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Transcription Program of Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus)
... and herpesvirus saimiri (32). Analysis of the HHV-8 genome reveals a number of conserved sequences, as would be expected in any herpesvirus, including those which encode virion structural proteins ...
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