human induced pluripotent stem cell
Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis
... by human-induced pluripotent stem cell-derived mesenchymal stem cells (hiPS-MSC-Exos) could promote angiogenesis of ischemic tissue in limb ischemia and skin defects [17, ...and ...
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hUCMSC-extracellular vesicles downregulated hepatic stellate cell activation and reduced liver injury in S. japonicum-infected mice
... of human-induced pluripotent stem cell-derived EVs reduces development of fibrosis and TGF-β1- induced HSC activation in an experimental model of cholestatic liver fibrosis ...
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The potential and limitations of induced pluripotent stem cells to achieve wound healing
... multiple cell types and ...therapies. Stem cell therapy is emerging as a potential treatment for chronic wounds, and adult-derived stem cells are currently employed in several commercially ...
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Pluripotent stem cells for Parkinson's disease: progress and challenges
... by human trials using fetus- derived DA neurons, provide compelling evidence to justify the development of these cells for use in human clinical ...between human and rat cells in the brain or a ...
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Induced pluripotent stem cells in infections
... It is only a decade since the concept of induced pluripotent stem cells came into existence. Initial efforts to culture iPSCs and further carrying out preclinical studies on murine and primates gave ...
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Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury
... Mesenchymal stem cells (MSC) are special cells with multi-lineage differentiation abilities ...for cell-based medical therapies because of their multi-lineage differentiation potential and ability to ...
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3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders
... ZIKV induced cell death in neuroepithelial progenitors, attenuated the proliferation of progenitor cells, and increased the size of lumen within ventricular ...ZIKV-infected human fetal brain ...
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Generation of induced pluripotent stem cells from large domestic animals
... Huang and collaborators showed similarity to our non- proliferating bovine colonies obtained when human OKSM was used. Zhao et al. [47] reported the mainten- ance of biPSCs for more than 50 passages when repro- ...
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Effects of mechanical stimulation on the reprogramming of somatic cells into human-induced pluripotent stem cells
... At 14 days after being placed on STO cells, all of the transduced dermal fibroblasts on the plate (diam- eter = 60 mm) in human ES cell medium were fixed and stained for ALP. Fewer colonies were stained in ...
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Selection of human induced pluripotent stem cells lines optimization of cardiomyocytes differentiation in an integrated suspension microcarrier bioreactor
... 1). Cell line-to-line variations occurred [25, 32], possibly during the reprogramming phase of the iPSCs which are derived from various ...easy cell line with high differentiation potential in 2D monolayer ...
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Directly induced human Schwann cell precursors as a valuable source of Schwann cells
... iSCPs: Induced-Schwann cell precursors; iSCs: iSCP-derived Schwann cells; iPSC: Induced pluripotent stem cells; hESCs: Human embryonic stem cells; NCSCs: Neural crest ...
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Understanding Megakaryopoiesis And Thrombopoiesis Using Human Stem Cells Models
... Human stem cell models (CD34+ hematopoietic progenitors, embryonic stem cells and induced pluripotent stem cells (iPSCs)) are powerful tools for the study of ...
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Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells
... The in vitro cardiac differentiation from PSCs is simi- lar to heart development involving the primitive streak formation, the specification of the lateral mesoderm, and the generation of cardiac progenitor cells and ...
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Human development, heredity and evolution
... in human embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) technology have enabled the generation of human organoids (miniature versions of ...
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Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes
... Real-Time Cell Analysis (RTCA) Cardio system, which utilizes impedance tech- nology to quantify CM-beating properties, has been previously reported as an emerging method to quantify cardiac contractility ...
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Mesenchymal stem cells overexpressing IL-35: a novel immunosuppressive strategy and therapeutic target for inducing transplant tolerance
... of cell therapy, the discov- ery of human-induced pluripotent stem cells (hiPSCs) greatly promoted the development of regenerative medi- ...Schwann cell-like ...
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Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector
... In this report, we described the successful establish- ment of an initial series of 223 hiPSC lines, derived from 15 patients affected by 8 different diseases, which in- cluded autoimmune diseases such as SLE and PD, im- ...
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Electrospinning of poly (ester amide) fibres for mesenchymal progenitor cell differentiation
... utilized human BM-MSCs and PGA tubular scaffolds and cultured the cell-scaffold construct in a bioreactor for 8 weeks in an optimized culture medium to create small diameter blood vessels and examined the ...
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Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy
... expected, given its origin from neuroblastoma [25], and that these cells have been subjected to neural differenti- ation for 10 days in the presence of retinoic acid [38]. Interestingly, it was found that RD cells of ...
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Stem Cell Therapy: An Overview
... neural cell of eye – photoreceptor, interneuron and retinal ganglion cell or RGS- and essential supporting cell such as retinal pigment epithelium ...distinct cell types are conceivable target ...
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