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human induced pluripotent stem cells

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells

... of human induced pluripotent stem cells (hiPSCs) into NP-like cells in ...NP cells as well as strategies used to support healthy NP cell phenotypes for primary ...

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Genetic basis of neurological disorder with human  induced pluripotent stem cells

Genetic basis of neurological disorder with human induced pluripotent stem cells

... - human primates, mammalian model and animal ...in stem cell technology and cell cultures leads to new direction of producing neurological models for several neurological ...in stem cell technology ...

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Derivation of Corneal Keratocyte-Like Cells from Human Induced Pluripotent Stem Cells

Derivation of Corneal Keratocyte-Like Cells from Human Induced Pluripotent Stem Cells

... atoconus. Human induced pluripotent stem cells (hiPSCs) offer an abundant supply of cells from which any cell in the body can be ...crest cells (NCCs), the embryonic ...

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Feeder  and serum free establishment and expansion of human induced pluripotent stem cells

Feeder and serum free establishment and expansion of human induced pluripotent stem cells

... Although human induced pluripotent stem cells (hiPSCs) hold great promise as a source of differentiated cells for vast therapeutic implications, many obstacles still need to be ...

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Expansion of Human Induced Pluripotent Stem Cells on Synthetic Substrate in Defined Medium

Expansion of Human Induced Pluripotent Stem Cells on Synthetic Substrate in Defined Medium

... ABSTRACT Human induced pluripotent stem cells (hiPSCs) have the potential to generate patient- specific cells to treat many incurable diseases by cell replacement ...feeder ...

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Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells

Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells

... type, human induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to generate human brain microvascular endothe- lial cells (BMECs), which compose the ...

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Hurdles to clinical translation of human induced pluripotent stem cells

Hurdles to clinical translation of human induced pluripotent stem cells

... to stem cell ...allogeneic stem cell bank could offer an attractive source of PSCs on which to build innovative technolo- gies ...in stem cell technology if the product derivative has not been ...

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Cornea organoids from human induced pluripotent stem cells.

Cornea organoids from human induced pluripotent stem cells.

... 3,000 cells were added per well of a round bottom 96 well ...) cells were transitioned to a Neural induction medium: consisting of DMEM (#11965; Invitrogen) with 1% B27 vitamin A (-) (#12587010; Invitrogen) ...

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Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology

Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology

... Keywords: induced pluripotent stem cells, polyamidoamine dendrimer-modified magnetic nanoparticles, fluorescent magnetic nanoparticle, preparation, label Introduction Since induced ...

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Effects of mechanical stimulation on the reprogramming of somatic cells into human-induced pluripotent stem cells

Effects of mechanical stimulation on the reprogramming of somatic cells into human-induced pluripotent stem cells

... the cells cultured without stimulation and simply cultured them, we could acquire the least number of iPSC colonies among the three groups set in this test (Group ...the cells with stretching (8% strain for ...

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Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte like cells

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte like cells

... epithelial cells 1 , which regulate bile homeostasis and modulate inflamma- tory ...These cells are also known as cholangiocytes and represent the main cell type affected in cholangiopathies 2,3 —a diverse ...

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Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells

Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells

... Methods: Human monocyte-derived DCs were induced and cultured in the presence or absence of ...successfully induced MSCs from different clones of human ...of human monocyte-derived DCs ...

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Signature of circular RNAs in human induced pluripotent stem cells and derived cardiomyocytes

Signature of circular RNAs in human induced pluripotent stem cells and derived cardiomyocytes

... RNA-Seq System V2 (NuGEN, CA, USA), as per the manufacturer’s instructions. Barcoded libraries were then prepared using the NEBNext® DNA Library Prep Master Mix Set for Illumina®, followed by gel excision and extraction ...

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Inhibition of LSD1 promotes the differentiation of human induced pluripotent stem cells into insulin-producing cells

Inhibition of LSD1 promotes the differentiation of human induced pluripotent stem cells into insulin-producing cells

... Results: Differentiated hiPSCs were 38.32% ± 3.54% insulin-positive cells and released insulin/C-peptide in response to glucose stimulus in a manner comparable to adult human islets. Most of the IPCs ...

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Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells

Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells

... studied human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) measuring the SNPs and CNVs with Affymetrix SNP 6 microarrays and ...

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Induced pluripotent stem cells in the study of neurological diseases

Induced pluripotent stem cells in the study of neurological diseases

... iPS cells into neurons is inhibition of pathways such as those of transforming growth factor beta and bone morphogenetic protein ...iPS cells diff erentiate to neuroepithelia usually within a few days of ...

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Induced pluripotent stem (iPS) cells from human fetal stem cells

Induced pluripotent stem (iPS) cells from human fetal stem cells

... iPS cells derived from fetal tissues for clinical applications Generating iPS cells for clinical application aims at avoiding the potential risk of insertional mutagenesis associated with the random ...

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EMBRYONIC STEM CELLS/INDUCED PLURIPOTENT STEM CELLS

EMBRYONIC STEM CELLS/INDUCED PLURIPOTENT STEM CELLS

... C ONCLUSIONS In this study, we show that a reporter line for Lmx1a can be used to isolate neural progenitors biased toward the GABAer- gic or the dopaminergic neuron fate depending on the culture method used for ...

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Pluripotency of induced pluripotent stem cells

Pluripotency of induced pluripotent stem cells

... somatic cells from various mammalian species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic expression of four transcription factors that are highly ...

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Mouse induced pluripotent stem cells

Mouse induced pluripotent stem cells

... iPS cells in human therapeutics is the risk posed by retroviral transduction of the three/four transcription ...treat human disease is so vast as to warrant extensive ...modify cells is to ...

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