human keratinocyte
Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease
... immunoprecipitate disulfide linked polypeptides of 170, 145, 125, and 95 kD in human keratinocyte culture media in a pattern identical to that of P1E1, a murine monoclonal antiepiligrin antibody. ...
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ROS-dependent Bax/Bcl2 and caspase 3 pathway-mediated apoptosis induced by zineb in human keratinocyte cells
... Abstract: There are a large number of agricultural workers who are exposed to pesticides through skin and inhalation. The best approach to identify altered molecular pathways during dermal exposure to pesticides is ...
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Hypoxia increases human keratinocyte motility on connective tissue
... when human keratinocytes are covered with occlusive dressings that induce ...conditions. Human keratinocytes apposed to col- lagens or fibronectin exhibited increased motility when sub- jected to hypoxic ...
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Identification and induction of human keratinocyte derived IL 12
... the human keratinocyte cell line HaCat expressing IL-12 p35 and p40 mRNA upon ...using human haptenated epidermal cells containing Langerhans cells as APC and allogeneic CD4+ T cells as ...
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Human keratinocyte culture Identification and staging of epidermal cell subpopulations
... of human epidermal cells into multilayered sheets composed of basal and suprabasal layers (resembling the stratum germinativum and stratum spinosum of the epidermis) was studied in a dermal component-free culture ...
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Schilling, David (2003): Stress and Growth Related Keratinocyte Pathways: Investigation of the Novel Immediate Early Gene IEX-1 in Primary Human Keratinocytes and the HaCaT Human Keratinocyte Cell Line. Dissertation, LMU München: Medizinische Fakultät
... primary human keratinocytes and the human keratinocyte derived, spontaneously immortalized HaCaT cell ...the keratinocyte model must be kept in mind: interaction between dermis and epidermis, ...
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Efficient induction of functional ameloblasts from human keratinocyte stem cells
... in human embryonic dental mesenchymal tis- sues that are able to induce nondental epithelial tissues, such as human keratinocyte, and able to participate in tooth formation ...that human ...
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Effectiveness of Cultured Human Keratinocyte Onlays on Epithelial Healing and Clinical Outcome After Photorefractive Keratectomy
... Despite the existing controversy regarding the degree to which epithelial healing and visual outcomes after refractive surgery are related, severely delayed epithe- lial healing is possibly an important cause of corneal ...
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Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector
... into human keratinocytes ...keratinocytes, keratinocyte proliferation and main- tenance of the stem/progenitor ...into human epi- dermal keratinocyte stem/progenitor cells cultured on a feeder ...
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A Plasmid vector encoding functional human keratinocyte growth factor gene in vitro—Functional human KGF gene expression in vitro
... cloned human KGF (hKGF) genes using RT-PCR techniques and developed a eukaryotic expression plasmid vector capable of directing the expression of functional ...of human embryo lung fibro- blast (HLF) was ...
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Original Article Therapeutic effects of recombinant human keratinocyte growth factor-2 on hyperoxia-induced bronchopulmonary dysplasia in neonatal rats
... meanwhile, keratinocyte growth factor-2 (KGF-2) plays a key role in lung ...recombinant human KGF-2 (rhKGF-2) in a hyperoxia-induced BPD rat model and explore the potential underlying ...
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Extensive tissue regenerative capacity of neonatal human keratinocyte stem cells and their progeny
... they demonstrate significant cell and tissue-regenera- tive capacity, despite the fact that they are destined to differentiate terminally if left unperturbed in vivo. We speculate that consistent with the spiral model of ...
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The effect of UVA irradiation on the DNA damage response in a human keratinocyte cell line
... The UVA-induced bystander effect was investigated in terms of how DDR initiation changes over time following irradiation of feeder cells with 100 kJ m-2 UVA, which has previously been de[r] ...
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Exosomes are involved in mediating radiation induced bystander signaling in human keratinocyte cells
... compared with healthy donors (31). The protein B7-H3 has been detected in exosomes released after radiation-induced senescence in 22 RV1 prostate cancer cells (32). Increased expression of B7-H3 protein has been ...
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High resolution imaging of TGFΒ3 treated human keratinocyte via a newly developed widefield surface plasmon resonance microscope
... Abstract— In this study high resolution imaging of human adult (HaCaTs) Keratinocytes cells using the newly developed Widefield Surface Plasmon Resonance (WSPR) system will be discussed. Surface Plasmon Resonance ...
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Natural variants of the human papillomavirus type 16 E6 protein differ in their abilities to alter keratinocyte differentiation and to induce p53 degradation.
... Naturally occurring variants may display biological differ- ences other than those described here which might affect their pathogenicity. For example, variant-specific differences might occur in host immune response as a ...
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Use of a Rho kinase inhibitor to increase human tonsil keratinocyte longevity for three-dimensional, tissue engineered tonsil epithelium equivalents
... The conditioned media from S. pyogenes-infected and control tonsil equivalents were analysed for cytokine content using Human Cytokine Antibody Array C3 (RayBiotech, Norcross, GA) in accordance with the ...
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Molecular damage and responses of oral keratinocyte to hydrogen peroxide
... The research protocol and consent form were approved by the Institutional Review Board (IRB) for Human Studies of National Cheng Kung University Medical Center (approval ID: A-BR-102-017). Informed consents from ...
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Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis
... densities. Keratinocyte cultures incubated with [14C]arachidonic acid synthesized prostaglandin (PG)E2 PGD2, PGF2 alpha, and small quantities of 6-keto-F1 ...
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Keratinocyte-Secreted Laminin 5 Can Function as a Transient Receptor for Human Papillomaviruses by Binding Virions and Transferring Them to Adjacent Cells
... Human papillomaviruses (HPVs) replicate only in the terminally differentiating epithelium of the skin and mucosa. While infection of basal keratinocytes is considered a requirement for permissive infection, it ...
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