HUMAN KERATINOCYTES
Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor
... Primary human keratinocytes are useful for studying the pathogenesis of many different diseases of the cuta- neous and mucosal ...primary keratinocytes have a finite lifespan in culture that limits ...
9
Human Papillomavirus Type 31b Infection of Human Keratinocytes Does Not Require Heparan Sulfate
... 40-transformed human keratinocytes), which have been reported to display heparin-dependent ...trast, human keratinocytes may express the specific receptor(s) at much higher levels, minimizing ...
10
HPV16 E5 deregulates the autophagic process in human keratinocytes
... of human papillomavirus type 16 (HPV16 E5) perturbs epithelial homeostasis down-regulating the expression of the keratinocyte growth factor receptor (KGFR/FGFR2b), whose signaling induces ...in human ...
17
Antiapoptotic effects of scutellarin on ultraviolet A-irradiated HaCaT human keratinocytes
... in human keratinocytes that are altered by UVA ...on human keratinocytes al- tered by UVA and suggest the applicability of scutellarin as an anti-aging cosmetic ...
8
Combined Transcriptome and Proteome Analysis of Immortalized Human Keratinocytes Expressing Human Papillomavirus 16 (HPV16) Oncogenes Reveals Novel Key Factors and Networks in HPV-Induced Carcinogenesis
... immortalized human keratinocytes (normal oral keratinocytes [NOKs]) (29) with a well-defined expression of HPV16 oncogenes and the corresponding parental negative-control ...
23
Human Papillomavirus Type 31b Infection of Human Keratinocytes and the Onset of Early Transcription
... We detected HPV31b infection of human keratinocytes by 4 h p.i. using RT-PCR techniques to assay newly synthesized, spliced viral RNAs. Thus, viral penetration, nuclear transport, and uncoating can be a ...
10
Protective effects of cynin on human keratinocytes (hacat) against uv-b
... Increased exposure to Ultraviolet-B (UV-B) radiation is the major risk for various skin injuries. Numerous studies have shown that bioproducts could demonstrate photopreventive efficacy against UV-B damage. Herein, we ...
8
Human Papillomavirus E6E7-Mediated Adenovirus Cell Killing: Selectivity of Mutant Adenovirus Replication in Organotypic Cultures of Human Keratinocytes
... primary human keratinocytes (hereafter referred to as raft ...study human adenovirus replication, we chose to perform this study in the raft system rather than in submerged cultures, because (i) ...
10
Proopiomelanocortin derived peptides are synthesized and released by human keratinocytes
... whether human keratinocytes are able to produce POMC-derived ...of human normal keratinocytes and an epidermal carcinoma cell line (A431) contained significant levels of immunoreactive alpha ...
6
Kaposi's Sarcoma-Associated Herpesvirus Can Productively Infect Primary Human Keratinocytes and Alter Their Growth Properties
... epidermal keratinocytes may play a significant role as regulators in inflammation and host immune ...Long-term-proliferating keratinocytes exhibited a different pattern of human cytokine production ...
9
Methicillin Resistant Staphylococcus aureus Adaptation to Human Keratinocytes
... within human keratinocytes is likely an important factor in its success as a skin ...within human ker- atinocytes is not ...that human nasal carriage of the same ...within ...
14
Development of a micro extruder with vibration mode for microencapsulation of human keratinocytes in calcium alginate
... = human adult, Ca = calcium, T= temperature) was designed to indicate its origin and the initial culture conditions of normal human ...normal human adult skin keratinocytes at reduced calcium ...
52
Anti-inflammatory effects of prunin on UVB-irradiated human keratinocytes
... The skin is put under oxidative stress when UV radiation induces the formation of reactive oxygen species (ROS), which damage DNA, lipids, and proteins (Devasagayam and Kamat 1994). Ultraviolet light acts as an external ...
6
Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition
... It is well known that the STAT3 Ser727 residue is phosphorylated mainly by Erk1/2, p38 MAPK, JNK and mTOR [37-40]. Our results showed that everolimus acti- vated Erk and p38 MAPK and phosphorylated STAT3 at Ser727, which ...
10
Myc and Human Papillomavirus Type 16 E7 Genes Cooperate To Immortalize Human Keratinocytes
... moderately) in both cell lines containing E7 (Fig. 4A). In these two cell lines, the level of pRb corresponds with the level of E7 (Fig. 2B) due to the known ability of E7 to facilitate the degradation of pRb (9). From a ...
7
1,25 Dihydroxyvitamin D3 production by human keratinocytes Kinetics and regulation
... Human foreskin keratinocytes in vitro metabolize 25-hydroxyvitamin D3 to a number of metabolites, including 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). This metabolite remains mostly within the cell and does ...
11
Activation of endogenous opioid gene expression in human keratinocytes and fibroblasts by pulsed radiofrequency energy fields
... cultured human dermal fibroblasts (HDF) and human epider- mal keratinocytes (HEK), we investigated the effect of PRFE treatment on factors, which are involved in modulating peripheral analgesia in ...
11
Destabilization of the Retinoblastoma Tumor Suppressor by Human Papillomavirus Type 16 E7 Is Not Sufficient To Overcome Cell Cycle Arrest in Human Keratinocytes
... Several hypotheses could explain why E7 CVQ68-70AAA and ⌬79–83 do not overcome antiproliferative signals in kera- tinocytes. Perhaps CVQ68-70AAA and/or ⌬79–83 do not in- activate p21, a CDK inhibitor important for cell ...
11
Thrombospondin induced adhesion of human keratinocytes
... epidermal keratinocytes obtained from normal skin attached and spread on thrombospondin (TSP)-coated plastic dishes but failed to attach and spread on untreated plastic culture dishes or dishes coated with ...
9
Effects of staphylococcus aureus on human keratinocytes
... and human umbilical vein endothelial cells (Peacock et al, 1999) showed that there was more than 90% reduction of its ...not human endothelial cells, was reduced by approximately 50% to 60% (Mempel et al, ...
251