Human lactoferrin
AN INVESTIGATION OF THE PROTONATION STATES OF HUMAN LACTOFERRIN IRON-BINDING PROTEIN
... of human lactoferrin in various conformations were investigated theoretically, at physiological pH ...of lactoferrin will trigger the opening of protein and release of iron ...
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Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11)
... Human lactoferrin 1-11 (hLF1-11) is a lactoferrin deriva- tive being developed for the treatment of bacterial and fungal infections in HSCT ...'natural' human protein, hLF1-11 might have the ...
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Electrochemical Studies on Bactericidal Mechanism of Human Lactoferrin and Its Demand for Microenvironment
... The bactericidal mechanism of human lactoferrin (LF) was analyzed by employing bioelectrochemistry technique. The result showed that LF bound to lipopolysaccharides (LPS) and caused release of LPS, ...
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Human lactoferrin but not lysozyme neutralizes HSV 1 and inhibits HSV 1 replication and cell to cell spread
... min at 37°C with different concentrations of human non-iron-saturated Lf (apoLf), iron-saturated Lf (satLf) or lysozyme (hLz) prior to inoculation of Vero cell cultures. Preincubated virus/hLf mixtures were ...
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Antifungal Effects of Lysozyme and Lactoferrin against Genetically Similar, Sequential Candida albicansIsolates from a Human Immunodeficiency Virus Infected Southern Chinese Cohort
... and lactoferrin contribute to mucosal protection and modulate Candida populations in the oral ...in human immunode- ficiency virus (HIV)-infected individuals significant variations in the concentrations of ...
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Original Article A method to induce high expression of human lysozyme in the milk of transgenic mice
... of human lactoferrin (hLF) in the hLF BAC clone with that of hLYZ, which is optimized for the hLYZ expression vector, five transgenic mouse lines were generated, four of which expressed rhLYZ at levels from ...
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Immunomodulatory properties of human recombinant lactoferrin in mice: Implications for therapeutic use in humans
... Mice were sensitized with OVA in cFa at the base of the tail and 4 days later, the reaction was elicited by injection of OVA in iFa in each of the hind foot pads, as described in Material and methods section. Recombinant ...
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Expression, purification and characterisation of antimicrobial peptides of human and bovine lactoferrins : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry at Massey University, Palmerston North, New Zealand
... recombinant human lactoferrin (rhLF) on ...kDa lactoferrin binding protein (Lbp) was identified from outer membrane proteins of ...that human lactoferrin supports growth of ...from ...
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Characterization of a new horse transferrin variant : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University
... A schematic diagram of the complete human lactoferrin molecule showing the positions of carbohydrate attachment for a variety of transferrin types including rabbit and human transferrin [r] ...
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Induction of Lactoferrin Gene Expression in Myeloid or Mammary Gland Cells by Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax: Implications for Milk-Borne Transmission of HTLV-1
... Our results suggested that HTLV-1 Tax transactivator played a role, at least to a certain degree, in such paracrine FIG. 4. Identification of cis-acting elements on the human lactoferrin gene promoter. (A) ...
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STRUCTURAL ASPECTS OF LACTOFERRIN AND SERUM TRANSFERRIN OBSERVED BY FTIR SPECTROSCOPY
... of human lactoferrin, which was assigned to N≡C or C=C stretch and C-H deformation vibrations of ...of human lactoferrin is linked to the tryptophan presence in its polypeptide ...of ...
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Spectroscopic Studies on Titanium Ion Binding to the Apolactoferrin
... General. To avoid contamination by extraneous metal ions, all glassware were soaked in a solution of concentrated nitric acid and rinsed with distilled and deionized water before use. Plasticware was pre-washed with 10 ...
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... into human milk and its health benefits has resulted in numerous ...on human milk components: human lactoferrin, human milk oligosaccharides, the probiotic derived from human ...
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Prevention of nosocomial infections in critically ill patients with lactoferrin (PREVAIL study): study protocol for a randomized controlled trial
... Bovine lactoferrin; CRP: C- reactive protein; DDD: Defined daily dose; hLF: Human lactoferrin; ICU: Intensive care unit; IL: Interleukin; KGH: Kingston General Hospital; LF: Lactoferrin; OR: ...
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Mechanisms Affecting the Gut of Preterm Infants in Enteral Feeding Trials
... Preterm delivery is associated with an increased risk of mortality and serious morbidities. Among these late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) are of particular concern. Adverse neurodevelopmental ...
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Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance
... The implications of iron/lactoferrin imbalance in the de- velopment of COPD might go beyond increasing bacterial growth. A recent discovery demonstrated that a gene that encodes for an iron receptor protein was ...
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Interactions of whey protein isolate and human saliva, as related to the astringency of whey protein beverages : a thesis in partial fulfilment of the requirement of the degree of Master of Technology in Food Technology at Riddet Institute, Massey University, New Zealand
... unheated/heated lactoferrin and saliva both showed a significant increase in particle size at readjusted pH ...heated lactoferrin and saliva between readjusted pH ...heated lactoferrin alone did not ...
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The responsiveness of the bovine lactoferrin promoter to cytokines and glucocorticoids : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University
... The bovine lactoferrin bLf promoter contains many putative binding sites for inflammatory modulators, which suggests that the increases in lactoferrin seen during inflammation may be due[r] ...
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The bovine lactoferrin gene : defining the minimal promotor region : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry
... 3.2.3 Examination of the 5' Deletion Mutants of the Bovine Lactoferrin Promoter 50 3.2.4 Examination of the 3' Deletion Mutants of the Bovine Lactoferrin Promoter Short Construct 3 'Dele[r] ...
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Antimicrobial activity of innate immune molecules against Streptococcus pneumoniae, Moraxella catarrhalis and nontypeable Haemophilus influenzae
... proteins, human milk lysozyme (Sigma, St. Louis, MO), human milk apo-lactoferrin ...MO), human β defensin-1 and human β defensin-2 (Peptides International, Louisville, KY), were ...
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