Human leukocyte antigen A
THE PROFILE OF HUMAN LEUKOCYTE ANTIGEN CLASS I IN PATIENTS WITH SCHIZOPHRENIA
... of Human Leukocyte Antigen (HLA) class 1 (A&B) alleles in the selected sample of schizophrenic patients in Iraqi ...One human leukocyte antigen -A gene (A*03) and two ...
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Blighted Ovum: Roles of human leukocyte antigen-E and natural killer cells
... Human Leukocyte Antigen-E has a very import- ant role in the development of pregnancy. Class I antigens are expressed on trophoblast that can help the fetus to avoid the maternal immune system ...
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Functional disruption of human leukocyte antigen II in human embryonic stem cell
... peptides presented by HLA II and HLA I, respectively. At the same time, those APCs must express a spectrum of costimulatory molecules (e.g., CD80 and CD86), which will interact with complementary molecules of T cells ...
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Resistance to anti-PD-1-based immunotherapy in basal cell carcinoma: a case report and review of the literature
... Case presentation: A 78-year-old woman was diagnosed with a metastatic non-small-cell-lung-cancer. Following the lack of response to two lines of systemic chemotherapy, she was treated with the anti-PD-1 monoclonal ...
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Natural Killer Cell Dysfunction in Hepatocellular Carcinoma: pathogenesis and clinical implications
... 32-36). Human liver-resident NK cells are characterized by expression of CXCR6 and CD69, have a distinct transcriptional and functional signature, and display memory-like features ...These human ...
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Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis
... above, and our results demonstrating that Actinobacteria been enriched in AS patients, we speculated that Actino- bacteria might modulate the ubiquitination of IκB-α. This in turn would allow the activation of NF-κB ...
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A Study of Human Leukocyte D Locus Related Antigens in Graves' Disease
... unrelated controls and 41 patients with Graves' disease were typed for seven HLA DRw specificities. 28 patients with Graves' disease (68%) were positive for DRw3, in contrast to 14 controls (28%); whereas only 21 ...
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Neuropathology of SUDEPRole of inflammation, blood-brain barrier impairment, and hypoxia
... and human leukocyte antigen–antigen D related (HLA-DR) would be more globally upregulated in control regions and in key autonomic-regulatory ...
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Studies with human leukocyte lysosomes Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases
... lysosomal antigen in SLE and related disorders was also ...to human lysosomes in immunodiffusion, a soluble lysosomal component, apparently distinct from the sedimentable (membrane-associated) ...
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Association of human leukocyte antigen-DRB haplotype in multiple sclerosis population of Khuzestan, Iran
... 6. Gregersen JW, Kranc KR, Ke X, Svendsen P, Madsen LS, Thomsen AR, et al. Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature 2006; 443(7111): 574-7. 7. Krogsgaard M, Wucherpfennig ...
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Evolution of the levels of human leukocyte antigen G (HLA G) in Beninese infant during the first year of life in a malaria endemic area: using latent class analysis
... Apart from pregnancy, HLA-G has been shown to be expressed in many types of tumours [8–11]. Tumour cells express HLA-G to escape to immunity and high levels of soluble HLA-G (sHLA-G) have been related with unfa- vourable ...
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Activation of monocytes and platelets by monoclonal antibodies or malaria infected erythrocytes binding to the CD36 surface receptor in vitro
... CD36 leukocyte differentiation antigen, recognized by MAbs OKM5 and OKM8 and found on human monocytes and endothelial cells, has been implicated as a sequestration receptor for erythrocytes infected ...
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Clinical review: flow cytometry perspectives in the ICU from diagnosis of infection to monitoring of injury induced immune dysfunctions
... studying human clinical samples, particularly in infl ammatory Figure ...monocyte human leukocyte antigen-DR expression (mHLA-DR) measurements, the gated region includes all monocytes and the ...
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Can a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: study protocol for the multicentre randomised controlled OuTSMART trial
... Two types of study have linked antibodies (Ab) against human leukocyte antigen (HLAs) to immune-mediated injury and premature graft failure. Case – control studies have compared patients who have ...
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An ontology for major histocompatibility restriction
... this MHC restriction, which can be determined in different manners, is the goal of the work presented here. Most MHC molecules consist of two protein chains, of which at least one gene is present within the MHC locus. In ...
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Investigation of Human Leukocyte Antigen (HLA) Class I and II Alleles and Hepatitis C Virus (HCV) Genotypes in Patients Infected with HCV
... Hepatitis C virus (HCV) is a major public health problem with more than 130 -180 million people infected worldwide. Several studies in different populations have reported the association of human leukocyte ...
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Significant Associations of the rs3104413 Single-nucleotide Polymorphism in the HLA Region with Type 1 Diabetes
... Type 1 diabetes (T1D) is a multifactorial disease in which immune system cells destroy pancreatic β-cells responsible for producing insulin in body [1]. T1D is a disease of major public health concern [2]. It is ...
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Tri-Allelic Human Leukocyte Antigen (HLA) Protection Against Dementia
... antigen (HLA) DRB1*13:02, a class II allele. HLA genes, which are located in the Major Histocompatibility Complex (MHC) of chromosome 6, code for cell-surface glycoproteins that facilitate the elimination of ...
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Hepatitis B virus genotypes, expression quantitative trait loci for ZNRD1-AS1 and their interactions in hepatocellular carcinoma
... Zinc ribbon domain-containing 1 (ZNRD1) is a zinc finger-related protein cloned from human leukocyte antigen (HLA) [7]. HLA is an important control gene for immune characteristics, and previous data ...
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Activities of stromal and immune cells in HPV-related cancers
... HLA: Human leukocyte antigen; HLA-DR: Human leukocyte antigen D related; HNSCC: Head and neck squamous cell carcinoma; HPV: Human Papillomavirus; hrHPV: High risk HPV; ...
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