human leukocyte antigens
Human leukocyte antigens‑immunogenetics of neuromyelitis optica or Devic’s disease and the impact on the immunopathogenesis, diagnosis and treatment: a critical review
... Since its very first discovery and disease association studies in early 1970’s, the major histocompability complex (MHC) with its polymorphisms has been the “gold standard” and the primer genetic locus in attributing ...
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MOLECULAR BASIS OF HUMAN LEUKOCYTE ANTIGENS DQB1*0201 ALLELE AND ITS ASSOCIATION WITH TYPE 1 DIABETES MELLITUS OF IRAQI CHILDREN
... Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex interaction of both genetic and immunologic factors. Similar to the majority of autoimmune diseases, T1DM usually has a ...
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Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition
... SPR measurement and analysis. All SPR experiments were conducted at 25 ° C on the BIAcore 3000 instrument (GE Healthcare) with HBS buff er (10 mM Hepes [pH 7.4], 150 mM NaCl, and 0.005% surfactant P20). The HBS buff er ...
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Human Leukocyte Antigens A*3001 and A*3002 Show Distinct Peptide-Binding Patterns of the Mycobacterium tuberculosis Protein TB10.4: Consequences for Immune Recognition
... Recombinant proteins. Recombinant MHC class I molecules were produced as described before (1, 17). Briefly, the heavy and light chains were produced as inclusion bodies in Escherichia coli BL21(DE3)pLys (Invitrogen, ...
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Maternal and child human leukocyte antigens in congenital cytomegalovirus infection
... HLA antigens, of the number of HLA mismatches (mm) and non-inherited maternal antigens (NIMAs) in a large retrospective nation-wide cohort of children with cCMV and their ...HLA antigens could not be ...
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HLA Class Ii Allele and Haplotype Associations with Type 1 Diabetes in Jeddah, Saudi Arabia
... the human leukocytes antigen (HLA) region ...The human leukocyte antigen (HLA) class II heterodimeric molecules consist of the alpha and beta chains and are encoded by numerous different alleles, ...
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Effect of one year of a gluten free diet on the clinical evolution of irritable bowel syndrome plus fibromyalgia in patients with associated lymphocytic enteritis: a case control study
... Questionnaire; FMS: fibromyalgia syndrome; GFD: gluten-free diet; GSE: gluten-sensitive enteropathy; HAQ: Health Assessment Questionnaire; HLA: human leukocyte antigens; HP: Helicobacter[r] ...
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Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts
... HLA: Human leukocyte antigens; GvT: Graft versus tumor; GvH: Graft versus host; MICA/B: Major Histocompatibility Class I-like molecules A and B; ULBPs: UL16 Binding Proteins; MAC: Myeloablative ...
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Congenital Autoimmune Neutropenia in Two Premature Neonates
... to human leukocyte antigens (HLA) can react in these assays, therefore, a monoclonal antibody immobilization of granulocyte antigens as- say (MAIGA) 2 was performed to differentiate between ...
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Current perspectives on antibody-mediated rejection after lung transplantation
... Abstract: The role of donor-specific antibodies (DSA) to human leukocyte antigens and the burden of antibody-mediated rejection (AMR) in lung transplantation remain enigmatic. Over the past several ...
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Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides
... the O type (H antigen) had higher infection rates than individuals expressing other blood types, while those with the B type were resistant to infections (5). Human noroviruses are genetically and antigenetically ...
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Human Paplllomavirus DNA and Virus Encoded Antigens in Cervical Carcinoma
... Human Papillomavirus DNA and Virus encoded Antigens in Cervical Carcinoma ORIGINAL ARTICLE Human Papillomavirus DNA and Virus encoded Antigens in Cervical Carcinoma A Padmanathan, MSc *, M Yadav, PhD*[.] ...
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Activities of stromal and immune cells in HPV-related cancers
... HLA: Human leukocyte antigen; HLA-DR: Human leukocyte antigen D related; HNSCC: Head and neck squamous cell carcinoma; HPV: Human Papillomavirus; hrHPV: High risk HPV; ICAM: ...
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Clinical review: flow cytometry perspectives in the ICU from diagnosis of infection to monitoring of injury induced immune dysfunctions
... Recently, neutrophil CD64 has been shown to be a highly sensitive and specifi c marker for systemic infection and sepsis [7]. Th e membrane molecule defi ned by monoclonal antibody CD64 is a high-affi nity receptor (FcγRI) ...
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HLA DR histocompatibility leukocyte antigens permit cultured human melanoma cells from early but not advanced disease to stimulate autologous lymphocytes
... melanoma cells and autologous lymphocytes and its dependence on HLA-DR expression, we have established cell lines from biologically early (4 lines) and advanced disease (11 lines) and examined their capacity to stimulate ...
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Biomechanical activation: an emerging paradigm in endothelial adhesion biology
... in leukocyte recruitment ...activation antigens in human and animal tissues in vivo, in various acute and chronic inflammatory processes, provided further validation of this paradigm ...
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Human minor Histocompatibility antigens.
... For over five decades minor histocompatibility (mH) antigens have contmued to fascmate immimologists, mainly because of their minor but distinct role in transplantation but no less becau[r] ...
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Direct quantitative measurement of the kinetics of HLA specific antibody interactions with isolated HLA proteins
... different HLA antibody/HLA allele combinations, in the order of 0.1nM to 10.0nM. We have shown that the signal obtained displays the expected HLA specificity and we can discern a distinct signal for low nanomolar ...
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Effects of Steroid Hormones on Human Polymorphonuclear Leukocyte Lysosomes
... PMN leukocyte lysosomes isolated from human volunteers receiving prednisolone were not more stable than control organelles, nor did serum from steroid-treated humans protect intact lysosomes from detergent ...
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Polymorphonuclear leukocyte and monocyte chemoattractants produced by human fibroblasts
... Fractionation of TABLE VI human serum that had been activated with fibroblast Effect of Collagenase on the Chemotactic Activity supernate on Sephadex G-75 indicated the chemoof Fibroblas[r] ...
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