Human lung cancer cells
Avicequinone B sensitizes anoikis in human lung cancer cells
... Avicequinone B, naphtho [2, 3-b] furan-4, 9-dione iso- lated from mangrove tree such as Avicennia alba and Avicennia marina has been shown to possess several pharmacological activities [21]. Anticancer activity of ...
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Combination of azacitidine and trichostatin A decreased the tumorigenic potential of lung cancer cells
... of human lung cancer cells, NCI-H1975 and NCI-H1299 cells, treated with various doses of inhibitors of DNA methyltransferase (azacitidine [5-AZA]) or histone deacetylase inhibitors ...
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Phytochemical analysis and antiproliferative studies of various extracts of mollugo cerviana
... Normal Human Dermal Fibroblast cells (NHDF), Human Cervical Cancer cells (HeLa), Human Liver Cancer cells (HepG2), Human Lung cancer ...
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Delivery of baicalein and paclitaxel using self-assembled nanoparticles: synergistic antitumor effect in vitro and in vivo
... In this study, prodrugs of PTX and BCL, containing dual- targeted ligands of FA and HA, were synthesized. Multifunc- tional self-assembled NPs for the combination delivery of PTX prodrug and BCL prodrug were prepared and ...
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ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR 34a expression
... 344SQ cells, which have high ZEB1 and low miR-34a expression (Figure ...344SQ_miR-34a cells proliferated at a rate similar to that of 344SQ_vector cells and demonstrated no biochemical evidence of ...
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Differential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells
... Cells were prepared for standard Western blotting. The mem- branes were incubated overnight at 4 ° C with primary mouse monoclonal antibodies against p-ERK1/2 (Thr202/Tyr204; E-10; 1:2,000, Cell Signaling ...
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IL-24 modulates the high mobility group (HMG) A1/miR222 / AKT signaling in lung cancer cells
... and cancer metastasis in a range of human cancers, such as colorectal cancer [12], ovarian cancer [13], head and neck tumor [14], glioblastomas [15], pancreatic cancer [16], breast ...
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<p>EFEMP2 Suppresses the Invasion of Lung Cancer Cells by Inhibiting Epithelial-Mesenchymal Transition (EMT) and Down-Regulating MMPs</p>
... In human osteosarcoma, EFEMP2 knockdown could sup- press the invasion and metastasis of osteosarcoma cells by inhibiting EMT, meanwhile EFEMP2 up-regulation could enhance the invasion and metastasis of ...
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CKAP4 is a Dickkopf1 receptor and is involved in tumor progression
... promote cancer cell proliferation, but the mechanism is not ...in cancer cell ...normal cells and cancer ...of human pancreatic and lung cancers, and simultaneous expression of ...
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Influence of the Metastatic Microenvironment on Stem-like Human Breast Cancer Cells
... disseminated cancer cells, interactions between these cells and the microenvironment will likely promote colonization and secondary tumour formation 106 ...of cancer cells reaching the ...
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The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo
... The human pancreatic cancer cell line PANC-1 was obtained from the Cell Resource Center for Biomedical Research, Institute of Development, Aging and Cancer, Tohoku ...The human ovarian ...
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Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells
... various lung cancer cells, including small lung cancer cells and non-small lung cancer ...non-small lung cancer cells than that in small ...
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Functional disruption of macrophage migration inhibitory factor (MIF) suppresses proliferation of human H460 lung cancer cells by caspase-dependent apoptosis
... H460 cells to obtain more sensitive and quantitative details of a pos- sible apoptotic mode of cell death (Figure 6A and ...H460 cells, flow cytometry was used to quantify the ex- pression of Annexin-V in ...
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<p>Differential Expression And Effects Of Peroxiredoxin-6 On Drug Resistance And Cancer Stem Cell-Like Properties In Non-Small Cell Lung Cancer</p>
... undifferentiated cells that contribute to the pathogenesis and progression of tumors, CSCs have been found in a variety of cancers, including myeloid leukemia, glioblastoma, gastric, and epithelial ...for ...
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Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development and Therapy
... inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells. 1005[r] ...
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The Role of CHMP4C on Proliferation in the Human Lung Cancer A549 Cells
... The human lung cancer has high incidence rate and mortality among the carcinoma. The research on enhancing the efficacy of therapy for lung cancer is significant. A resent research ...
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m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis
... in human lung cancer tissues and cancer cells than in normal adjacent lung tissues and control cells, respectively ...in human lung tumor tissues (T) com- ...
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Evaluation of Anti-cancer and Pro-apoptotic Activities of Iranian Green Tea Extract Against A549,PC3, and MCF-7 Cancer Cell Lines
... different human cancer cell lines including human non-small-cell lung cancer A549 cells, human prostate cancer PC3 cells, and human breast ...
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P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors
... Carbonic anhydrase XII (CAXII) is a membrane enzyme that maintains pH homeostasis and sustains optimum P-glycoprotein (Pgp) efflux activity in cancer cells. Here, we investigated a panel of eight CAXII ...
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A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer
... degradation, with the appearance of lower mobility bands (Fig. 1f and g), which resembled the effect of PTC-028 as re- ported [29]. Therefore, our results suggest QW24 treatment might induce the hyperphosphorylation of ...
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