human lung mast cells
Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells
... Purified human lung mast cells released histamine, leukotrienes, prostaglandin (PG) D2, thromboxane B2 (TxB2), and PGF2 alpha in response to anti-IgE ...the cells for 24 h with 10(-6) M ...
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Generation of leukotrienes by purified human lung mast cells
... from mast cells and basophils plays a central role in the pathogenesis of human allergic disease, biochemical studies have been restricted to rat peritoneal mast cells and basophilic ...
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Prostaglandin D2 generation from human lung mast cells is catalysed exclusively by cyclooxygenase-1
... in mast cells since our own studies demonstrate that LPS is a strong inducer of COX-2 in lung macrophages (Fig S1, Supporting Information ...in human lung mast cells ...
40
Mast cells in human airways: the culprit?
... that mast cell heterogeneity in humans goes beyond the division into MCT and MCTC ...the lung create an expanded ‘‘site-specific’’ heterogeneity (figs 2 and 3) ...between human lung ...
9
Mast cell exosomes promote lung adenocarcinoma cell proliferation – role of KIT-stem cell factor signaling
... from human mast cells can be taken up by lung cancer cells, the HMC-1 exo- somes were labeled with PKH67 dye and added to cul- tures of A549 ...A549 cells after the addition of ...
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Mast cells in a murine lung ischemia-reperfusion model of primary graft dysfunction
... of mast cells in human lung pathology is that the numbers and distribution of mast cells differ between laboratory mice and ...of mast cells to pathology in mice is ...
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Differential effects of the complement peptides, C5a and C5a des Arg on human basophil and lung mast cell histamine release
... induce mast cell leukotriene C4 (LTC4) and prostaglandin D2 (PGD2) ...C5a-challenged mast cells remained fully active on basophils, excluding carboxypeptidase inactivation of C5a as an explanation ...
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Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2
... stimulated mast cells, showed no differences compared to the non-stimulated mast ...of mast cell tryptase in ...with mast cells and CM could be that different factors are ...
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Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts
... of human mast cells is the serine protease ...to mast cells, where tryptase exists within the secretory granules in a complex with heparin proteoglycan ...in mast cells ...
10
Pharmacological antagonism of mast cell secretion in human lung tissue
... Sodium cromoglycate, salbutamol and chlorpromazine have been studied for their effects on antigen-induced histamine release from mast cells in passively sensitised human lung tissue... T[r] ...
217
Human mast cells decrease SLPI levels in type II – like alveolar cell model, in vitro
... with mast cell activation [40]. Mast cells are multifunctional cells capable of secreting a wide variety of cytokines, chemok- ines and growth factors ...by mast cells can ...
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Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro
... Mast cells play an important role in both adaptive and innate immunity and show increases in immunological skin diseases, including dermatitis ...for mast cells ...stimulation, mast ...
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Activation of human mast cells by retrocyclin and protegrin highlight their immunomodulatory and antimicrobial properties
... that human blood proteins (like insulin, interferon, etc), when expressed in chloroplasts are properly folded with disulfide bonds and are fully functional upon oral or injectable delivery [68, ...of human ...
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Association of mast cells with lung function in chronic obstructive pulmonary disease
... for mast cells in COPD, since they secrete ...Indeed mast cells generally have detrimental effects in various inflam- matory conditions ...However, mast cells can have quite ...
9
Enhancement of basophil chemotaxis in vitro by virus induced interferon
... investigated the effect of cell-free supernates from viral stimulated cultures of human mononuclear cells on the in vitro migration of human basophils. Our results show the presence of a factor in ...
7
Serum IgE clearance is facilitated by human FcεRI internalization
... Antibodies. Human IgE was obtained from Abcam and BioFront Tech- nologies and was extensively dialyzed against PBS prior to in vivo experi- ments. Unlabeled antibodies for confocal microscopy included rabbit ...
13
The Channel-Kinase TRPM7 as Novel Regulator of Immune System Homeostasis
... Blood monocytes and tissue macrophages are major components of innate immunity, strategically positioned throughout the body tissues to orchestrate inflammatory processes. Similar to neutrophils, they maintain tissue ...
23
Dengue Virus Selectively Induces Human Mast Cell Chemokine Production
... ies. Mast cells are known to play an important role in host defense against several pathogens, but their role in viral infection has not yet been ...by human mast cells were ...HMC-1 ...
12
Phytochemical analysis and antiproliferative studies of various extracts of mollugo cerviana
... Normal Human Dermal Fibroblast cells (NHDF), Human Cervical Cancer cells (HeLa), Human Liver Cancer cells (HepG2), Human Lung cancer cells (A549) and ...
5
Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway
... of mast cells was positively correlated with CXCL12 production ...tumor cells (Additional file 7: Figure S2d) in the GC microenvir- ...of mast cells, mast cell chemotaxis assay ...
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