Human mesenchymal stem cell interactions with
Cell matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure
... To test this hypothesis, MSCs were encapsulated into hydrogels that either prevent (agarose) or promote (fibrin) cell attachment and spreading within the construct. Since it is heavily involved with blood clots, ...
28
Human Mesenchymal Stem Cell Functional Identification Kit
... ASSAY Stem cells are functionally defined by their capacity to self renew and their ability to generate a large number of differentiated progenitor cells, which commit to further maturation along specific ...
16
Defining human mesenchymal stem cell efficacy in vivo
... Allogeneic human mesenchymal stem cells (hMSCs) can suppress graft versus host disease (GvHD) and have profound anti-inflammatory and regenerative capacity in stroke, infarct, spinal cord injury, ...
12
Mesenchymal Cell Contributions to the Stem Cell Niche
... these cell populations in skeletal develop- ment and repair and in the regulation of hematopoietic ...the cell types and how they interact with each other, with neighboring cells of endothelial or neural ...
15
Human cardiac mesenchymal stem cell like cells, a novel cell population with therapeutic potential.
... MSC cell populations ...lineage cell, while the CMSCLC also showed early striation ...individual human heart tissue donors and showed that they expressed at varying levels; genes associated with ...
44
Extending the Window of Use for Human Mesenchymal Stem Cell Seeded Biological Sutures
... autologous cell isolation and expansion (to eliminate immune response to cells), mechanical function of the heart, engraftment rates of delivered cells, degradation of sutures in vivo, and long term effects of ...
116
Mesenchymal stem cell fate : applying biomaterials for control of stem cell behavior
... desired cell response and could also be biodegradable with the aim of being replaced with native tissue after the support and templating role was complete; second-generation biomaterials included hydroxyapatite ...
14
The hepatic stem cell niche and paracrine signaling by mesenchymal cells in support of human hepatic stem cells
... its stem cells is also likely to play a role in recruiting stem cells, a process referred to as ...both stem cells and the surrounding ...germline stem cell niches are experimentally ...
276
Localisation of corneal epithelial progenitors and characterization of cell-cell interactions in the human limbal stem cell niche
... single cell clonal analysis suggesting the existence of stem cells outside of the ...which stem cells, of equal potency are distributed throughout the entire ocular surface, expand in opposite ...
237
Mechanisms of mesenchymal stem/stromal cell function
... certain cell types through secretion of so-called trophic factors and even presented the notion that they could regulate certain facets of the immune ...enhance cell viability and/or prolifera- tion, reduce ...
13
NEWER ADVANCES IN MESENCHYMAL STEM CELL THERAPY
... organizations. Mesenchymal stem cells (MSCs) are procured through many body origins usually by the placenta as well as the umbilical cord but other sources like bone core derived MSCs are also important as ...
6
Mesenchymal stem cell transformation and sarcoma genesis
... transformation has been demonstrated in both mouse and human MSCs. Transformed MSCs of both species can give rise to pleomorphic sarcomas after transplantation into mice, indicating the potential MSC origin of ...
9
The Effect of Hypoxia on Mesenchymal Stem Cell Biology
... Remarkably, expression of VEGF-A transcription is up to 20 times higher under hypoxic environments through osteogenesis than during adipogenesis. Additionally, analysis of PPARG expression (a key marker for ...
9
A Review of Mesenchymal Stem Cell Injections for Osteoarthritis
... of stem cells injected is far from ...slow cell expansion process used in autologous harvest, but theoretically may cause host immune rejection; no adverse reactions were identified in an RCT by Vega et ...
20
Define mesenchymal stem cell from its fate: Biodisposition of human mesenchymal stem cells in normal and. Con-A induced liver injury mice
... revolutionized mesenchymal stem cell-based ...of human mesenchymal stem cells in normal and Con A induced liver injury ...calculated. Human and mice MSCs (hMSCs and mMSCs) ...
41
Mesenchymal stem/stromal cell function in modulating cell death
... Abstract Mesenchymal stem/stromal cells (MSCs) delivered as cell therapy to individuals with degenerative and/or inflammatory disorders can help improve organ features and resolve inflammation, as ...
12
Mesenchymal stem cell effects on T-cell effector pathways
... Mesenchymal stem (stromal) cells (MSCs) are rare, multipotent progenitor cells that can be isolated and expanded from bone marrow and other ...helper cell) subsets Th1, Th2, and Th17 cells and ...
9
Keywords: mesenchymal cell osteoarthritis, stem cell, umbilical cord
... cord-mesenchymal stem cells differentiation assay [11] Chondrogenic differentiation For chondrogenic differentiation, the pellet culture system described by Sekiya et ...
7
Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord
... After storage for 20 minutes at room temperature in the dark, 400 μL of PBS supplemented with 2% FCS were added and analyzed in the EPICS XL/MCL flow cytometer (Beckman Coulter GmbH). Living cells were gated in a dot ...
8
Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering
... for human mesenchymal stem cell culture in tissue engineering Abstract The design of new bioactive scaffolds mimicking the physiologic environment present during tissue formation is an ...
42