human neural stem/progenitor cells
Identification and Classification of Hubs in microRNA Target Gene Networks in Human Neural Stem/Progenitor Cells following Japanese Encephalitis Virus Infection
... of neural stem/progenitor cells (NSPCs), hence the focus of our current ...JEV-infected human neuronal progenitor cells and pri- mary neural precursor cells ...
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Neural stem and progenitor cells in cancer and development
... contain cells that, in clonal cultures, produce cells expressing neuronal and/or glial markers (Ignatova et ...some cells from pediatric brain tumors (primarily medulloblastomas and astrocytomas), ...
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CHD7 promotes proliferation of neural stem cells mediated by MIF
... precursor cells) in vivo [18], suggesting possible diverse roles for Chd7 that vary in a manner dependent on spatial and developmental ...of neural crest cells based on the binding to the target ...
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GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells
... for Stem Cell Biology, Univer- sity of Sheffield, under a HTA licence for potential clinical application ...specific neural differentiation potential of these clinical-grade lines which have been deposited ...
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Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells
... neuroectodermal cells were visualized by immunostaining with antibodies against SOX2 (red) and PAX6 (green) (D) or SOX2 (red) and NESTIN (green) ...H9 cells were cultured in the ESC medium with the addition ...
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Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells
... in neural induction medium (NIM) (DMEM/F12, 1% NEAA, 1% GlutaMAX, 1% N2, 2% B27, and 10 ng/ml ...positive cells using double BMP/SMAD inhibition (data not ...emerging neural rosettes were manually ...
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Manifestation of Huntington’s disease pathology in human induced pluripotent stem cell-derived neurons
... to human neurons, the complexity of the molecular mecha- nisms underlying HD pathology, and the lack of ad- equate animal ...for human pluripotent stem cells (PSCs), have jointly engendered ...
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Single cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage
... of human iPSCs towards the neural lineage (Musah et ...differentiated cells into tissue-specific stem/ progenitor cells, which highlights the importance of mechanosensing for ...
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Stem cell researchers find their niche
... of stem cell numbers, and Weimin Zhong (Yale University, New Haven, CT, USA) asked whether stem cells use intrinsic asymmetric divisions to achieve ...for neural stem ...
5
Potential of adult neural stem cells for cellular therapy
... Neural stem cells (NSCs) are selfrenewing multipotent cells that generate the main phenotype of the nervous system, neurons, astrocytes, and ...oligodendrocytes. Neural ...
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Enhanced selective gene delivery to neural stem cells in vivo by an adeno associated viral variant
... NSCs, human fetal NSCs and human embryonic stem cell (hESC)- derived neural progenitor cells compared with AAV2 (Jang et ...to human NSCs was further enhanced (Kim et ...
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Functional similarities of microRNAs across different types of tissue stem cells in aging
... developing neural stem/progenitor cells (NSCs) by controlling the “competence” necessary for NSCs to respond to gliogenic cell-extrinsic signals [25, ...in human aging [33, ...
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The Specificity Protein 2 (Sp2) in the Proliferation and Cell Cycle Progression of the Neural Progenitors.
... with progenitor functions including regulation of the cell cycle (Baur et ...skin stem cell and progenitor populations is oncogenic (Kim et ...
157
Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling
... glial cells that modulates astrocyte proliferation as an autocrine through PKC activation ...embryonic stem cells (ESCs) and thus implies an important role in pluripotency signaling ...of ...
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The nanomaterial toolkit for neuroengineering
... mammalian cells, with the first in vitro demonstration using mammalian neurons in 2005 ...optically-manipulated neural activity with spe- cific behavioral changes in freely-moving mammals was reported ...of ...
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Jin, Jieqi (2018): The effects of low molecular weight hyaluronan on the cementogenic, ligamentogenic and osteogenic differentiation of human mesenchymal stem cells (hMSCs) and periodontal ligament cells (PDL-hTERTs). Dissertation, LMU München: Medizinische Fakultät
... Due to the effects on cell proliferation and its almost ubiquitous occurrence, HA at different molecular weights has been proposed to play a significant role in healing of damaged tissue (Jiang et al. 2007, Tolg et al. ...
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Age-related dysfunction of the DNA damage response in intestinal stem cells
... senescent cells promotes organismal aging and that senolytics improve age-associated phenotypes and pro- long lifespans [9 – ...Senescent cells secrete a myriad of inflammatory factors, a phenomenon termed ...
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A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... a stem cell source, the problem is that lack of uniform platform in current stem cell research leads to an inconsistent ...the stem cell, even more challenge to optimize a new therapy with current ...
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Less is More: Oxygen and Stem Cell Regeneration
... (CNS) stem cells are used extensively to study pathways leading to generation of neuronal and glial lineages (McKay, ...CNS stem cells can self-renew, and after mitogen withdrawal, ...
291
Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells
... stromal cells and growth factors has been utilized in an attempt to ex vivo recapitulate in- teractions in hematopoietic microenvironment to expand ...CB stem cells in clinical trials. Here we ...
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