human norovirus
Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality
... uman norovirus is the leading cause of acute viral gastroenteritis, responsible for about 125 million cases and a disease burden of ...for human norovirus have recently been reported (3, ...using ...
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Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion
... mouse norovirus neutralization potency iden- tified a single amino acid outside the antibody-binding site that mediated antibody binding by changing particle conformation ...on human norovirus ...
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Epigenetic Suppression of Interferon Lambda Receptor Expression Leads to Enhanced Human Norovirus Replication In Vitro
... of human cell lines bearing stable human norovirus ...several human cell lines stably replicating HuNoV ...generate human norovirus replicon cells ...
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Structural Basis for Human Norovirus Capsid Binding to Bile Acids
... Indeed, human histo-blood group antigens (HBGAs) interact with the capsid, and this binding interaction is an observed requirement of infection for most but not all GI and GII genotypes ...of human ...
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Characterizing Human Norovirus Binding to Fresh Strawberries.
... route, human norovirus (HuNoV) is shed by infected individuals at high concentrations (up to 10 11 per g of feces) (Atmar et ...five norovirus infections in a 79-year lifespan (Hall et ...
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Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities
... to human health. Here, we report that the protein NS3 encoded by human norovirus has both ATP- dependent RNA helicase activity that unwinds RNA helices and ATP-independent RNA-chaperoning activity ...
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Characterization of human norovirus binding to gut associated bacterial ligands
... with human norovirus ...complete human antigen for positive blood group activity [7], which may explain the ubiquitous nature of bacterial HBGAs observed in this ...
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Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides
... protein. Human norovirus is difficult to grow in cell cultures, and the exact locations of the cells and the cell type(s) that norovirus infect remain ...The norovirus particle is composed of ...
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Prevalence of Human Norovirus by Genotype in Contaminated Groundwater in Korea Over the Last Decade (2007-2016)
... Human Norovirus (HuNoV) is a member of the family Caliciviridae, which can be subdivided into more than 32 genetic clusters ...Most human HuNoV infections due to groundwater were of genotypes GI and ...
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Characterizing Human Norovirus-Bacteria Interactions.
... ligands potentially responsible for these interactions. Seven bacteria (E. cloacae, S. aureus, Klebsiella spp., Bacillus spp., E. faecium, Citrobacter spp., and H. alvei) were evaluated via Western blot using antibodies ...
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Pathogenesis of a Genogroup II Human Norovirus in Gnotobiotic Pigs
... We evaluated the gnotobiotic (Gn) pig as a model to study the pathogenesis of human norovirus (HuNoV) and to determine the target cells for viral replication. Sixty-five Gn pigs were inoculated with fecal ...
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Development of a Nanobody-Based Lateral Flow Immunoassay for Detection of Human Norovirus
... ABSTRACT Human noroviruses are the dominant cause of outbreaks of acute gas- ...(ELISA). Human noroviruses are genetically and antigenically diverse, with two main genogroups that are further subdivided ...
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A Mouse Model for Human Norovirus
... the human stools present in the GII mix (see Table S1 in the supplemental material) was not re- covered from infected mice (see Table S2 in the supplemental ...
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A large outbreak of acute gastroenteritis caused by the human norovirus GII.17 strain at a university in Henan Province, China
... The epidemic curve showed two peaks of incidence. The first peak appeared on the seventh day after the first case occurred, continuing to 20 March. Cases with onset during these 11 days accounted for 85.29% of all ...
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Evidence for Human Norovirus Infection of Dogs in the United Kingdom
... Serological analysis of 325 canine serum samples in this study strongly suggests that dogs mount immune responses against HuNoV. We have demonstrated that almost 20% of dogs sampled in 2012 to 2013 had antibodies that ...
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Alternative Chemical Disinfection Technologies for Inactivation of Human Norovirus on Surfaces.
... inactivate human NoV on stainless steel surfaces (measured by RT-qPCR both with and without RNase treatment) at the same concentration and exposure time (250 ppm FAC, 1-min) was significantly reduced ...
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Human Norovirus Evolution in a Chronically Infected Host
... of norovirus gastroenteritis occurred there within the 13-month ...acute norovirus infection that lasted approximately 6 ...Thereafter, norovirus could be isolated repeatedly, leaving him as a ...
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Review of the Practical Considerations of Human Norovirus Detection in Foods and Environmental Samples.
... chimpanzees to observe Norwalk symptoms, and to detect the agent from fecal samples, but similar to human subjects, ethical inquires would arise. Soon after discovery of the Norwalk virus, Alder et al. (1969) ...
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Evidence for human norovirus infection of dogs in the UK
... Serological analysis of 325 canine serum samples in this study strongly suggests that dogs mount immune responses against HuNoV. We have demonstrated that almost 20% of dogs sampled in 2012 to 2013 had antibodies that ...
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Diagnostic Accuracy and Analytical Sensitivity of IDEIA Norovirus Assay for Routine Screening of Human Norovirus
... IDEIA Norovirus assay in our study is similar or higher than previously reported results (5, 11, 12, 19, ...IDEIA Norovirus kit uses a cocktail of monoclonal and polyclonal antibodies generated against ...
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