Human obesity
Genetic Aspects of Human Obesity: A Review
... in human brain, gut, placenta and pancreas, is involved in the leptin/melanocortin ...have obesity, a defective adrenal development and an altered ...prevalent obesity gene, being involved in 1 to 4% ...
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Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects
... in human obesity, we have determined, using a modification of the euglycemic glucose clamp technique, the shape of the in vivo insulin-glucose disposal dose-response curves in 7 control and 13 obese ...
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Erratum to: Physiological models of body composition and human obesity
... Correction to Levitt DG, Heymsfield SB, Pierson Jr RN, Shapses SA, Kral JG: Physiological models of body composition and human obesity.. This is an Open Access article distributed under [r] ...
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Preserved endothelial function in human obesity in the absence of insulin resistance
... hand, obesity has long been related to IR and increased ...in human obesity, allowing for preserved endothelial function in obese people when ...in human obesity and the mechanisms ...
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Splanchnic lipolysis in human obesity
... One of the limitations of the model we employ to estimate the proportion of hepatic FFA delivery originating from visceral adi- pose tissue lipolysis is that if FFAs are released directly into the hepatic venous ...
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The art of targeting gut microbiota for tackling human obesity
... Major concerns regarding FMT include the absence of safety measures, the lack of a standardized treatment regime and the potential encouragement of patients to try the treatment at home without medical supervision (Sil- ...
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Skeletal muscle munc18c and syntaxin 4 in human obesity
... Fast- ing for 48 hours did not change Syntaxin 4 (Figure 2), but significantly decreased Munc18c content in lean and obese subjects (Figure 1). These data suggest prolonged fasting decre[r] ...
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Physiological models of body composition and human obesity
... Equation 2, which is simply an empirical polynomial fit to the data, is also not physiological, going to negative val- ues at large BMI. In contrast, eq. 3 used by Gallagher et. al. [5] is valid in the limit of large BMI ...
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Genome wide association study identifies KCNMA1contributing to human obesity
... severe obesity in most cases is a condition at the extreme of the phenoty- pic spectrum rather than a distinct condition, which suggests that the same genes are involved in all obese patient groups of the same ...
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Insulin Binding to Monocytes and Insulin Action in Human Obesity, Starvation, and Refeeding
... FIGURE 4 Correlation between the specific binding of 1251_ insulin per 1 x 107 monocytes/ml at tracer 0.2 ng/ml concentration of insulin and the in vivo insulin sensitivity as indicated [r] ...
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Cholesterol Metabolism in Human Obesity
... Table I presents the sterol balance data obtained in this group of eight obese patients, from which daily synthesis rates were calculated by subtracting the daily cholesterol intake from[r] ...
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Gene-nutrient interactions and susceptibility to human obesity
... how obesity susceptibility genes interact with environmental factors to increase weight gain, in what has formally become known as “gene-environment inter- actions,” defined as a response or adaptation to an ...
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Genetic approaches to understanding human obesity
... trolytic lesioning studies to be critically regulated at the level of the hypothalamus (12, 13). Parabiosis experiments in inbred strains of mice with severe obesity, such as ob/ob and db/db, suggested the ...
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Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
... causing human obesity alone (Obesity Alone; n = 6); (2) genes in which known variants cause human obe- sity combined with developmental delay and/or dysmorphology (Obesity and Delay; n ...
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Correlation between Obesity and Inflammation in Cardiovascular Diseases—Evaluation of Leptin and Inflammatory Cytokines
... PBMCs. The in vitro study also shows that the mRNA level of TNF- α, IL-6, Ob-Rb increases with increase in leptin concentration. Also, these cytokines have been found to be significantly overexpressed in obese subjects. ...
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Genomics, obesity and enhancement: moral issues regarding aesthetics and health
... Obesity is often associated with a lack of self-discipline and the ideal nowadays appears to be “effortless thinness”. This reminds one of the old sin of gluttony. Thinness therefore tends to be seen not (only) as ...
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'I'd kill anyone who tried to take my band away' : obesity surgery, critical fat politics and the 'problem' of patient demand
... about obesity surgery; not a censuring of those claims, but rather, the recognition of the exclusions that they produce, of the resistances at work and of the ...
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Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the “1,2,3 diet” in a moderately obese population
... cates that an increase in cheese consumption can beneficially modify the gut microbiota to increase short-chain fatty acid (SCFA) levels when compared to diet containing butter. The evidence for a potential role of SCFA ...
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The prevalence of general and abdominal obesity according to sasang constitution in Korea
... general obesity between males and females. The preva- lence of general obesity as determined by BMI was higher in males than in females, whereas the prevalence of AO by WC and WHR was similar in males and ...
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“NUTRIGENOMICS – A NON- CONVENTIONAL THERAPY” by Shibani N. Bhatt*, Arthvan D. Sharma, India.
... of human lung cancer cells which undergo apoptosis, whole green tea is more effective than the individual constituents of the green tea in inhibiting TNF-α ...
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