Human pituitary
Pituitary directed leukemia inhibitory factor transgene forms Rathke's cleft cysts and impairs adult pituitary function A model for human pituitary Rathke's cysts
... of pituitary LIF during development se- lectively inhibits or stimulates adenohypophyseal ...the pituitary-directed LIF transgenic mice, forma- tion of cystic cavities associated with hypo-expression of GH ...
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The identification of human pituitary adenoma-initiating cells
... tumors, pituitary adenomas account for 10% of diagnosed intracranial ...of human brain tumor-initiating cells (TICs) that initiate and maintain tumor growth while promoting disease progression and relapse ...
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Targeted expression of a human pituitary tumor–derived isoform of FGF receptor 4 recapitulates pituitary tumorigenesis
... this pituitary tumor–derived, N-terminally truncated FGFR4 cDNA, and to further exclude the possibility that alternative splicing or rearrangement was the mecha- nism responsible for this FGFR4 isoform, we adopted ...
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Distribution of beta endorphin immunoreactivity in normal human pituitary
... in human pituitary; however, the two peptides are not necessarily present in the same cells at all ...in human pituitary under conditions suitable for demonstration of the peptide in thyroid C ...
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THE CYTOLOGICAL LOCALIZATION OF ACTH IN THE HUMAN PITUITARY
... All frozen sections of human pituitaries treated with fluorescent anti-ACTH showed specific staining of cells and groups of cells in the pars anterior Figure 1, and scattered sparsely th[r] ...
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Studies on “Big” Growth Hormone from Human Plasma and Pituitary
... in human plasma elutes from Sephadex G-75 as “little” GH (LGH), mol wt 22,000, but 14-39% elutes earlier (“big” GH, ...of human pituitary, 11-17% of IRGH eluted as ...of pituitary and plasma ...
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Radioimmunoassay of β MSH in Human Plasma and Tissues
... A radioimmunoassay method for b-melanocyte-stimulating hormone (b-MSH) has been developed and utilized in the identification and quantification of this hormone in human plasma and tissues. The concentration of ...
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Cerovac, Vesna (2010): Studies on the PI3K/mTOR pathway as cytostatic treatment target in pituitary adenomas. Dissertation, LMU München: Fakultät für Biologie
... 9 The antiproliferative action of somatostatin and its analogs was attributed to their inhibitory action on the growth factor receptors (Tsuzaki & Moses, 1990; Lee et al., 1991; Florio et al., 1996). Sstr2 ...
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Mechanisms for pituitary tumorigenesis: the plastic pituitary
... malignancies. Pituitary tumors are invariably benign, and although aggressive local growth may occur, their general failure to proceed to true malignancy with demonstrable extracranial metastases is ...of ...
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Functional role of estrogen in pituitary tumor pathogenesis
... modulating pituitary angiogenesis and tumor ...that pituitary pttg is induced by estrogen and bFGF, the latter being expressed in a concordant fashion with pttg in experimental and human ...
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Extraction and characterization of a thyrotropic material from the human placenta
... both human and bovine pituitary TSH neutralized the biologic activity of the placental ...for human pituitary TSH; it cross-reacted completely in a radioimmunoassay for bovine pituitary ...
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Human and murine pituitary expression of leukemia inhibitory factor Novel intrapituitary regulation of adrenocorticotropin hormone synthesis and secretion
... that human pituitary cells express the LIF gene and LIF-binding sites, predominantly in ...corticotrophs. Pituitary LIF expression and LIF regulation of proopiomelanocortin and ACTH reflect an ...
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CDK5 and Its Activator P35 in Normal Pituitary and in Pituitary Adenomas: Relationship to VEGF Expression
... in pituitary adenomas are poorly ...normal human pituitary and in pituitary ...in pituitary adenomas than in the normal glands, suggesting that CDK5 activity might be upregulated in ...
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Somatostatin receptor subtype specificity in human fetal pituitary cultures Differential role of SSTR2 and SSTR5 for growth hormone, thyroid stimulating hormone, and prolactin regulation
... of human fetal pituitaries, at 23–25 wk of ...in human well differentiated somatotropes by 8 wk ...the human adenohypophysis between 12 and 15 wk (42, ...(45). Human pituitary cells are ...
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Shan, Bing (2010): The novel sumoylation enhancer RSUME is implicated in pituitary tumor pathogenesis. Dissertation, LMU München: Fakultät für Biologie
... from pituitary adenoma cell lines (TtT/GF and AtT-20) and primary human pituitary adenoma cell cultures was performed with TRIzol ® Reagent according to the manufacturer’s ...
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Evidence of a Congenital Midline Brain Anomaly in Pituitary Dwarfs: A Magnetic Resonance Imaging Study in 101 Patients
... Pituitary Volume of Patients With Single (IGHD) or Multiple (MPHD) Hormone Deficiency, Associated with Ectopic (PPE) or Normal (NPP) Posterior Pituitary (Pubertal Stage 3). n Pituitary[r] ...
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Malignant Lymphoma in the Parasellar Region
... PPL and SPL. Although the most common presentation is a pituitary insufficiency in both of these lymphomas, hypopituitarism is seen more often in PPL (73.7%) than SPL (41.2%), but there is no statistically ...
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Pituitary hemorrhage as a complication of hantaviral disease
... the pituitary gland develop in 50% to 100% of fatal cases and death can occur as a serious compli- cation after the hypotensive phase ...anterior pituitary gland was one of the most common sites of ...
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Hartlmüller, Daniela (2018): The effects of temozolomide on normal and tumoral pituitary cells. Dissertation, LMU München: Medizinische Fakultät
... In general, the primary culture cells that we investigated seemed to be less responsive to temozolomide compared to the pituitary cell lines. This is a common phenomenon, because cell lines have a higher ...
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Pituitary Apoplexy: A MRI Finding Case and Literature Review
... Conclusion: Pituitary apop- lexy is a rare but serious complication of pituitary ...neuro-ophthalmologic. Pituitary apoplexy involves the patient’s functional and vital prognosis due to acute ...
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