Human Platelet
Characterization of Human Platelet Vascular Permeability Enhancing Activity
... that human platelet lysosomal release of cationic proteins may increase vascular permeability by several mechanisms including endogenous histamine release as well as delayed ...
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Location of phosphatidylethanolamine and phosphatidylserine in the human platelet plasma membrane
... The location of phospholipids in the human platelet plasma membrane was probed with 2, 4, 6-trinitrobenzenesulfonate (TNBS). TNBS does not penetrate inintact cells and can label phosphatidylethanolamine ...
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Characterization of human platelet vasopressin receptors
... on human platelet ...to platelet receptors whereas no such relationship existed when antidiuretic activities were considered (r = ...of human platelets; on the contrary, high AVP ...
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Human platelet stimulation by acetyl glyceryl ether phosphorylcholine
... Acetyl glyceryl ether phosphorylcholine AGEPC induced dose-dependent platelet aggregation and release of [3H]serotonin and platelet factor 4 in citrated human platelet-rich plasma.. ADP [r] ...
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The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome
... the platelet transcriptome and proteome, which was recently highlighted after the first quantitative prote- ome was reported ...reference human platelet transcriptome, we had an opportunity to shed ...
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Extensive human platelet specific antigens typing of blood donors of different geographical origin to manage platelet transfusion in alloimmunized patients: Experience from a transfusion center in Northeastern Italy
... Aims: As a consequence of global migration flows the risk of HPA alloimmunization may be increased for recipients of platelets from ethnically diverse donors. In this study, the frequencies of HPA in donors of different ...
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Studies on human platelet protease activity
... from human platelets was fractionated by DEAE cellulose column chromatography and analyzed for protease activity using three substrates: denatured bovine hemoglobin, alpha casein, and purified plasminogen-free ...
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Studies on human platelet granules and membranes
... In the present study, the highest specific activity of acid phosphatase was in a portion of the granule band above the area of greatest specific activity of cytochrome c oxidase, indicat[r] ...
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Human Platelet Collagenase
... of platelet aggregation and was not a part of the release ...of platelet homogenates using appropriate sub-cellular markers indicated that collagenase appeared in both the granule and membrane ...in ...
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Increased Fluidity of Human Platelet Membranes during Complement Mediated Immune Platelet Injury
... platelets at 37°C, and this was associated with platelet lysis ( 51 Cr release). Complement damage to platelets was accompanied by a 10-15% increase in ΔE, the fusion activation energy for microviscosity, ...
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Heterogeneity of antibody response to human platelet transfusion
... aggregation with 30, 24, and 60%, respectively, of a donor population studied. The aggregating activities were inhibited by antihuman IgG but not by antihuman IgA or antihuman IgM antiserum. The aggregating antibodies ...
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Factors affecting human platelet function in relation to atherosclerosis
... that platelet phosphatidyl choline, the most abundant phospholipid in platelet membranes, was enriched in linoleic acid after the PUF ...of platelet membranes may be expected to result in an ...
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Effects of methanol and formic acid on human platelet aggregation
... inhibited platelet aggregation in a concentration-dependent manner irrespective of platelet stimuli ...on platelet aggregation independent of Ca 2+ ...thrombin-induced platelet aggregation in ...
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The intracellular pH of the human platelet
... The platelet is unable to maintain a constant pH, despite changes in bicarbonate concentration of 12.5 to 100 mEq per L, when external hydrogen ion activity is varied by increasing Pco2 [r] ...
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Studies on Human Platelet Gangliosides
... Gangliosides, glycosphingolipids which contain sialic acid, were studied in human platelets. They represented 0.5% of the platelet lipids and accounted for 6% of the total neuraminic acid content of ...
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Human platelet activation by adrenaline
... page 5.3.2 Potentiation of the ADP-response by Selective a-receptor Agonists in the Presence of BPB 133 5.3.3 A comparison of the Effects of TPCK and BPB on Adrenaline Potentiation 133 5[r] ...
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A monoclonal antibody to human platelet glycoprotein IIIa detects a related protein in cultured human endothelial cells
... against platelet membrane ...cultured human endothelial cells obtained from umbilical vein, internal iliac artery, and inferior vena ...per human umbilical vein endothelial ...of platelet GP ...
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Platelet function in brown bear (Ursus arctos) compared to man
... Information on the coagulation system in bears is scarce. Previous studies have studied haptoglobin and α 2 - macroglobulin and found both parameters to rise in brown and black bears (Ursus americanus) during hiber- ...
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Epidemiology and management of fetal and neonatal alloimmune thrombocytopenia
... Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease in pregnancy characterized by maternal alloantibodies directed against the human platelet antigen (HPA). These antibodies can cause ...
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Complex formation of platelet thrombospondin with histidine rich glycoprotein
... Thrombospondin and histidine-rich glycoprotein are two proteins with diverse biological activities which have been associated with human platelets and other cell systems. Using an enzyme-linked immunosorbent ...
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