human serum albumin binding
An integrated quantitative structure and mechanism of action-activity relationship model of human serum albumin binding
... the software DRAGON v. 7.0 [14] for the calculation of 5,325 MDs. An unsupervised feature reduction was applied to filter the constant ( > 80% ) and highly intercor- related descriptors (pairwise correlation among all ...
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Brain Derived Neurotrophic Factor Modulates Behavioral and Brain Responses to Social Stress
... upon binding to human serum albumin and their affect on ...The binding of the dye may elicit a response from the HSA that may affect its binding interaction with ...
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EFFECT OF COMPETITIVE BINDING OF HYPOGLYCEMIC AGENTS TO HUMAN SERUM ALBUMIN ON DRUG PHARMACOLOGY
... the binding of the antidiabetic drugs decreased in the presence of various competing drugs resulting in a significant increase in the concentration of free, pharmacologically active drug for several drug ...The ...
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A Thermodynamic Study on the Binding of Human Serum Albumin with New synthesized Anticancer Pd(II) Complex
... Where is the appearance association equilibrium constant as a function of Pd- anti-cancer concentration.Therefore for the first time, we managed to calculate and values with using one set of experimental data in one ...
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THE BINDING OF THIOCYANATE TO ALBUMIN IN NORMAL HUMAN SERUM AND DEFIBRINATED BLOOD WITH REFERENCE TO THE DETERMINATION OF “THIOCYANATE SPACE”
... Although these results permit a more accurate calculation of "thiocyanate space" than heretofore, the relation of this space to extracellular fluid volume is uncertain since 1 the concen[r] ...
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Investigation of the Interaction between Coumarins and Its Derivatives with Human Serum Albumin: STD-NMR, Fluorescence and Docking Molecular Studies
... The binding epitopes of the ligands in complex HSA are shown in Figure 1-c that informs the relative percentage of each chemical ...same binding epitope pattern, and the predicted binding mode is ...
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SOME QUANTITATIVE ASPECTS OF THE BINDING OF QUINIDINE AND RELATED QUINOLINE COMPOUNDS BY HUMAN SERUM ALBUMIN
... The interaction of albumin and the quinoline compounds related to quinidine is characterized by an increasing number of available binding sites in albumin and decreasing association cons[r] ...
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Investigation of binding of bovine serum albumin with metallic nanoparticles
... of serum albumin is to transport metabolites such as nutrients, hormones, fatty acids and a variety of ...Among serum albumins, human serum albumin (HSA) and BSA is extensively ...
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SPECTROSCOPIC AND ELECTROCHEMICAL INVESTIGATION OF BINDING OF NEVIRAPINE WITH BOVINE SERUM ALBUMIN
... Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) which belongs to dipyridodiazepinones chemical class. [1, 2] Nevirapine is used in combination with nucleoside analogs for treatment of Human ...
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Allosteric inhibition of cobalt binding to albumin by fatty acids : implications for the detection of myocardial ischemia
... cobalt- binding capacity of albumin, without the need to invoke oxidative stress or more complex mechanisms, we have studied the interactive effects of cobalt and fatty acid binding to albumin ...
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Study On The Binding Behavior Of Bovine Serum Albumin (Bsa) And Human Serum Albumin (Hsa) With Ceftriaxone: Spectroscopic Investigations
... contrary, Serum albumins of the circulatory system have various physiological functions, including the maintenance of osmotic pressure, transport, distribution, and participation in the metabolism of many ...
5
The Binding of Androsterone Sulfate, Etiocholanolone Sulfate, and Dehydroisoandrosterone Sulfate by Human Plasma Protein
... The binding of androsterone sulfate A-S, etiocholanolone sulfate E-S, and dehydroisoandrosterone sulfate D-S to human plasma, serum, and two albumin preparations Tritiated steroid plus a[r] ...
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AZORUBIN BINDING CAPACITY AND PROTEIN COMPOSITION OF SERUM OF RATS SUBJECTED TO TOURNIQUET SHOCK AND TO TREATMENT WITH CARBON TETRACHLORIDE
... Assuming the binding of azorubin to rat serum albumin and that to human serum albumin to be essentially similar, a difference of about 0.2 per cent would be expected between the specific[r] ...
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EQUILIBRIUM DIALYSIS STUDIES OF THE BINDING OF THYROXINE BY HUMAN SERUM ALBUMIN
... While other factors besides electrostatic attraction may be involved in binding, the data indicate an important role for the interaction of free cationic groups on the protein molecule a[r] ...
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Analysis of Binding Interaction between Captopril and Human Serum Albumin
... beings. Human serum albumin (HSA), the most abundant protein in human plasma, acts as a carrier for transporting many ligands, including fatty acids, amino acids, metal ions, and a variety of ...
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Molecular Structure of Thyroxine in Relation to Its Binding by Human Serum Albumin
... The data, to be reported separately in detail 6, suggest that the albumin molecule possesses a single strong binding site with an association constant approximating 500,000, a secondary [r] ...
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Fatty acid distribution in systems modeling the normal and diabetic human circulation A 13C nuclear magnetic resonance study
... distinct binding sites on human serum albumin, native human lipoproteins, and/or phospholipid model membranes, under conditions that mimic the normal and diabetic human ...
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Competitive Binding of Bilirubin and Drugs to Human Serum Albumin Studied by Enzymatic Oxidation
... The mechanism of drug-induced displacement of bilirubin from the blood into tissues was studied. A model of simple, competitive binding of bilirubin and drug to one site on serum albumin was ...
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Binding of naturally occurring hydroxycinnamic acids to bovine serum albumin
... protein binding is aromaticity of the ligand molecule because hydrophobic interactions are formed between aromatic rings of ligand and amino acid residues ...strongest binding affinity because this compound ...
8
1290.pdf
... Since aluminum behaves similarly to iron in many biological systems (for example binding to transferrin, discussed below), AP^ may also be taken up via the specialized iron absorption pathways found in the gut. As ...
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