Human T Lymphotropic Virus Type 1
Cloning and Expression of a Human T-Lymphotropic Virus Type 1 Protein with Reverse Transcriptase Activity
... of human T-lymphotropic virus type 1 (HTLV-1) reverse transcriptase ...the virus, our objective was to clone, express, and purify a functional RT enzyme from ...
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A Human T Lymphotropic Virus Type 1 Carrier Coinfected with Mycobacterium intracellulare and Pneumocystis jirovecii with a Characteristic Compositional Change of Bone Marrow Cells
... Human T lymphotropic virus type 1 (HTLV-1) is endemic in the southern part of ...the virus can cause adult T cell leukemia/lymphoma (ATL), while most ...
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APOBEC3A, APOBEC3B, and APOBEC3H Haplotype 2 Restrict Human T-Lymphotropic Virus Type 1
... The human APOBEC3 family consists of seven cytidine deaminases (A3A to A3H), some of which display potent antiretroviral activity against HIV-1 and other ...on human T-lymphotropic ...
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Gag Localization and Virus-Like Particle Release Mediated by the Matrix Domain of Human T-Lymphotropic Virus Type 1 Gag Are Less Dependent on Phosphatidylinositol-(4,5)-Bisphosphate than Those Mediated by the Matrix Domain of HIV-1 Gag
... C-terminal region of HTLV-1 MA, which contains the late domain motifs PPPY and PTAP (6), was excluded from the HTMA sequence (Fig. 1a). pCMV-RRE- HTLV-1-Gag-eCFP, pCMV-RRE-HIV-1-Gag-eCFP, and ...
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Complex Cell Cycle Abnormalities Caused by Human T-Lymphotropic Virus Type 1 Tax
... G 1 (red). The “Ad-Tax-trans- duced” cell, however, progressed through G 1 (red), G 1 /S tran- sition (yellow), S (green), and G 2 (green) slowly, as reflected ...
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Seroprevalence and geographical distribution of human T lymphotropic virus type 1 among volunteer blood donors in endemic areas of Iran
... As a routine procedure, all selected donors were tested for transfusion transmissible infections, including; HBV, HCV, HIV, Treponema pallidum and HTLV-1/2 at each blood transfusion center. HTLV-1/2 Ab Kit ...
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Human T Lymphotropic Virus Type 1 protein Tax reduces histone levels
... in human cells ...all T-cell lines exam- ined (both infected and uninfected), while PI fluorescence (DNA content) continued to increase in a near linear fash- ...
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Human T-Lymphotropic Virus Type 1 Transcription and Chromatin-Remodeling Complexes
... cloned viral DNA. ACH.WT was the first infectious HTLV-1 molecular clone containing the full-length HTLV-1 proviral genome from the CH strain and a wild-type C91/PL tax gene, and it is able to ...
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Simian foamy virus type 1 is a retrovirus which encodes a transcriptional transactivator.
... Certain oncoviruses, such as human T-lymphotropic virus type 1 HTLV-1, and certain lentiviruses, such as human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus, enc[r] ...
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Human T-Cell Lymphotropic Virus Type 1 Tax among American Blood Donors
... cutaneous T-cell lymphoma, mycosis fungoides (MF), harbor the tax se- quence of HTLV-1 in their lymphocytes without having anti- bodies to the structural proteins of the virus ...
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Human T-Cell Lymphotropic Virus Type 3: Complete Nucleotide Sequence and Characterization of the Human Tax3 Protein
... dithiothreitol, 1 mM; phenylmethylsulfonyl fluoride, 1 mM) in the presence of protease inhibitors (Complete; Boehringer), and incubated on ice (5). Cell debris was pelleted by centrifugation. The protein ...
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Enhanced specificity of truncated transmembrane protein for serologic confirmation of human T cell lymphotropic virus type 1 (HTLV 1) and HTLV 2 infections by western blot (immunoblot) assay containing recombinant envelope glycoproteins
... with human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 are widely distributed among recipi- ents of multiple blood transfusions, intravenous drug users, female ...
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Functional analysis of human T lymphotropic virus type 2 Tax proteins
... Tax 1 only reduced its activity while W248R abolished both LTR and NFkB activation by Tax ...Tax 1 W248R was expressed at a similar level to Tax 1 WT, Tax 1 Y144C was very poorly expressed ...
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A Cohort Study of Health Effects of Human T-Cell Lymphotropic Virus Type I Infection in Jamaican Children
... in his report on risk factors for maternal-child transmission of HTLV-I in this cohort. Briefly, 9430 pregnant women attending either of 2 antenatal clinics in Kingston, Jamaica, between January 1989 and August 1990 were ...
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Elevated Cyclic AMP Levels in T Lymphocytes Transformed by Human T-Cell Lymphotropic Virus Type 1
... the viral oncogenes StpC/Tip and Tio, respectively, showed only low cAMP levels (Fig. 2G) in comparison to HTLV-1-/ Tax-transformed cell lines (Fig. 1A and 2D). To exclude tet- racycline effects on cAMP levels ...
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Human T-cell lymphotropic virus type 1 Tax mediates enhanced transcription in CD4+ T lymphocytes.
... the 1-week coculture, transient transfec- tions, and in vitro transcription experiments were stimulated with mitogen to increase cell numbers and viral transcription as previously described for assays with ...
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Adenosine deaminase isoenzyme levels in patients with human T-cell lymphotropic virus type 1 and human immunodeficiency virus type 1 infections.
... in T cells, since ADA is directly associated with the extracellular domain of CD26, which is defined as one of many T-cell activation anti- gens ...ADA1 1 cp (280 kDa), and the levels of those ...
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Neuropilin-1 Is Involved in Human T-Cell Lymphotropic Virus Type 1 Entry
... FIG. 2. Overexpression of NRP1-enhanced HTLV-1 Env-medi- ated cell fusion. (A) Cell surface expression of endogenous NRP1 by HeLa-Tat and MDA-MB-453 cells. Cells were labeled with phyco- erythrin-coupled control ...
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Coactivator-Associated Arginine Methyltransferase 1 Enhances Transcriptional Activity of the Human T-Cell Lymphotropic Virus Type 1 Long Terminal Repeat through Direct Interaction with Tax
... We also analyzed the effect of the Tax mutations on HTLV-1 transcription (Fig. 4F). While WT Tax significantly increased HTLV-1 LTR transcription (lane 2), the Tax mutant del 151–204 was defective in Tax ...
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Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndrome.
... 1 Persistent Infection of Chimpanzees with Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus: A Potential Model for Acquired Immunodeficiency Syndrome Received 12 Augu[r] ...
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