human trigeminal ganglia
The High Prevalence of Herpes Simplex Virus Type 1 DNA in Human Trigeminal Ganglia Is Not a Function of Age or Gender
... in human trigeminal ganglia (TG) with respect to age, gender, and postmortem interval ...(PMI). Human TG (n ⴝ 174, obtained from the Oregon Brain Bank, with data on age, gender, and PMI) were ...
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Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell Infiltrates
... in human trigeminal ganglia ...in human TG. This indicates that viral latency in human TG might be controlled by other mechanisms such as viral ...
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Detection and preliminary characterization of herpes simplex virus type 1 transcripts in latently infected human trigeminal ganglia.
... In situ hybridizations of human trigeminal ganglia using probes homologous to the BamHI SP region detected HSV-1 RNA transcribed from the same strand as the 1.85- and 1.35-kb latency tra[r] ...
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Analysis of Human Alphaherpesvirus MicroRNA Expression in Latently Infected Human Trigeminal Ganglia
... of human ganglia for the presence of virally encoded ...of human trigeminal ganglia latently infected with two pathogenic alphaherpesviruses, herpes simplex virus 1 (HSV-1) and ...
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Epigenetic Regulation of Varicella-Zoster Virus Open Reading Frames 62 and 63 in Latently Infected Human Trigeminal Ganglia
... infected human TG. Three pairs of human TG obtained at autopsy (Table 1 lists the clinical de- tails) were analyzed for their association with H3K9(Ac) ...transformed human malignant melanoma cell ...
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Quantitation of Latent Varicella-Zoster Virus and Herpes Simplex Virus Genomes in Human Trigeminal Ganglia
... from human sensory nerve ganglia (1, ...tent ganglia reservoirs, each of these herpesviruses may cause significant clinical disease in the individual and may spread to uninfected ...
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Varicella-zoster virus (VZV) transcription during latency in human ganglia: construction of a cDNA library from latently infected human trigeminal ganglia and detection of a VZV transcript.
... DNA extracted from the human ganglionic cDNA library was PCR amplified by using primers specific for vector and for VZV ORFs contained within Sall C genes 17 to 21, and any amplified pro[r] ...
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Analysis of Individual Human Trigeminal Ganglia for Latent Herpes Simplex Virus Type 1 and Varicella-Zoster Virus Nucleic Acids Using Real-Time PCR
... both human and animal models ...in human ganglia removed at autopsy; however, nonneuronal sat- ellite cells are also implicated as a reservoir of latent VZV (11, 15; and reviewed in reference ...
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Varicella-Zoster Virus Transcriptome in Latently Infected Human Ganglia
... of human trigeminal ...all trigeminal ganglia was ...infected trigeminal ganglia (A to H), from a VZV DNA-negative trigeminal ganglion (I), from uninfected MeWo cells (J), ...
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Molecular Aspects of Varicella-Zoster Virus Latency
... Analysis of individual human trigeminal ganglia for latent herpes simplex virus type 1 695. and varicella-zoster virus nucleic acids using real-time PCR[r] ...
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Epigenetic Regulation in Neural Crest Development: Role of DNA Methyltransferases 3A and 3B
... 123 GFP embryos at stage 14 were sectioned and immunostained for active caspase-3 (casp-3), which is a robust marker for apoptotic cells. Given that we can detect a phenotype as early as stages 15–16, embryos were ...
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The zinc finger transcription factor GLI3 is a regulator of precerebellar neuronal migration
... nervous system (CNS) after E10.5 does not alter the formation of the precerebellar system. These results suggest that the abnormal migratory path of precerebellar neurons in Gli3 null mutants could be caused by: (1) ...
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A simian varicella virus (SVV) homolog to varicella-zoster virus gene 21 is expressed in monkey ganglia latently infected with SVV.
... monkey ganglia. We extracted poly(A) 1 RNA from mon- key ganglia latently infected with SVV and found it to be free of viral DNA by nested PCR (data not ...
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Cellular Transcription Factors Induced in Trigeminal Ganglia during Dexamethasone-Induced Reactivation from Latency Stimulate Bovine Herpesvirus 1 Productive Infection and Certain Viral Promoters
... Bovine herpesvirus 1 (BHV-1), an alphaherpesvirinae subfamily member, establishes latency in sensory neurons. Elevated corti- costeroid levels, due to stress, reproducibly triggers reactivation from latency in the field. ...
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Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene Promotes Neuronal Survival
... A complex interaction between the virus and the host de- termines the fate of cells infected by herpes simplex virus type 1 (HSV-1). At the body surface, about 77 known viral lytic- phase genes are actively transcribed ...
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Pathogenesis of Herpes Simplex Virus Type 2 Virion Host Shutoff (vhs) Mutants
... tion occurred despite reduced growth of the HSV-2 null mu- tants in the cornea and trigeminal ganglion. HSV-1 vhs null mutants, however, have a greatly reduced (up to 10,000-fold) ability to replicate in the ...
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Infectious Herpes Simplex Virus in the Brain Stem Is Correlated with Reactivation in the Trigeminal Ganglia
... important human health ...the trigeminal ganglia (TG) and the brain stem from the same latently infected animal using direct assays of equivalent ...
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A major portion of the latent pseudorabies virus genome is transcribed in trigeminal ganglia of pigs.
... C Uninfected pig trigeminal ganglion hybridized Regions outside of the BamHI-8 fragment as well as within it were subcloned into Bluescript, and ssRNA probes generated from each of these[r] ...
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In Vivo Reactivation of Latent Herpes Simplex Virus 1 in Mice Can Occur in the Brain before Occurring in the Trigeminal Ganglion
... 12-well plates seeded the day before. Brain stem homogenates were cen- trifuged. The resulting supernatant from one brain stem was distributed to nine wells of Vero cell monolayers, and the resulting pellet was resus- ...
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5 HTr Expression in Primary Trigeminal Neuron Following Injury
... of trigeminal gan- glia neurons in response to ...primary trigeminal neurons to injury is rather ...on trigeminal ganglia neurons, as they are significantly involved in pain ...
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