IFN-γ,IL-12
Plasma levels of TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD)
... TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 theoretically could contribute to the underlying etiology of ...achalasia. IL-17 is a key mediator in ...
7
IL 12–induced IFN γ is dependent on caspase 1 processing of the IL 18 precursor
... cytokines, IL-12 and IL-18, are currently regarded as the primary inducers of IFN-γ production in an inflammatory reaction (1, ...understood. IL-12 is a heterodimeric ...
8
Analysis of IL-12 p40 subunit gene and IFN-γ G5644A polymorphisms in Idiopathic Pulmonary Fibrosis
... the IFN-γ gene at position 5644 in the 3'UTR region (Accession No, M37265) and a functional polymorphism in the IL-12 p40 subunit gene at position 1188 in the 3' UTR region [17–19] in patients ...
5
Original Article Elevated plasma levels of IL-12 and IFN-γ in systemic lupus erythematosus
... 27]. IFN-γ, principally produced principally by T cells, CD4+ as well as CD8+, and natural killer cells, links innate and acquired response of macrophages [28, ...and IFN-γ levels) in SLE ...
6
IFN γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL 12/pulse IL 2 therapy
... therapy. IL-12 is an important immunoregulatory cytokine that enhances several functions of T and/or NK cells (1) and possesses potent IFN- γ –dependent therapeutic activity in various murine ...
13
Influenza Virus Vaccination Induces Interleukin-12/23 Receptor β1 (IL-12/23Rβ1)-Independent Production of Gamma Interferon (IFN-γ) and Humoral Immunity in Patients with Genetic Deficiencies in IL-12/23Rβ1 or IFN-γ Receptor I
... for IL-18 in IFN- ␥ production in response to the influenza virus ...case, IL-12 does not seem to play a critical role in the clearance of influenza virus infection in mice, and ...
5
Cytokines and T Helper Cells in Diabetic Nephropathy Pathogenesis
... Currently, IL-33 other interleukin belonging to IL1 family, has been ...that IL-33 has a complex feature [42] [43]. IL-33 role in DN is not well defined ...in IFN- γ , ...
17
Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with post-infectious irritable bowel syndrome
... secrete IFN-γ, IL-12, IL-2, and tumor necrosis factor-α (TNF-α), and mediate cellular immunity, while Th2 cells play a key role in promoting Th1 differentiation and the Th1 ...produce ...
6
Differential serostatus of Epstein-Barr virus in Iranian MS patients with various clinical patterns
... with IFN- γ, IL-12 and IL-4 cytokines production in MS patients with different clinical subtypes and healthy individuals for in- vestigating MS risk score in each clinical ...
7
Gamma Interferon (IFN-γ) and IFN-γ-Inducing Cytokines Interleukin-12 (IL-12) and IL-18 Do Not Augment Infection-Stimulated Bone Resorption In Vivo
... with IFN-␥ and its inducing cytokines are in sharp contrast to our previous findings with Th2 cytokines, several of which are potent suppressors of inflammatory re- sorption as noted ...Both IL-10-deficient ...
5
Original Article Docosahexaenoic acid suppresses pro-inflammatory macrophages and promotes anti-inflammatory/ regulatory macrophage polarization through regulation of cytokines
... (IFN-γ, IL-12, IL-4 and IL-10) was detected, with or without LPS chal- ...of IFN-γ, IL-12, IL-4, and IL-10 were ...of IL-10, ...
8
Acteoside inhibits inflammatory response via JAK/STAT signaling pathway in osteoarthritic rats
... 5, IL-1β, IL-6, IL-12, TNF-α and IFN-γ productions were significantly increased in synovial fluid of knee joint by surgery stimulation, whereas ACT treatment markedly reduced the ...
8
The IL 23/IL 17 axis in inflammation
... not IFN-γ and ...blocking IL-23 or its downstream factors IL-17 and IL-6, but not the IL-12/ IFN-γ pathways, can significantly suppress disease development ...
6
Schäffer, Nadia (2019): Proinflammatorische Zytokine und Allergien beim Tourette-Syndrom. Dissertation, LMU München: Medizinische Fakultät
... In einer anderen Studie konnte hingegen für ein breites Spektrum von Zytokinen und Adhäsionsmolekülen (IL-2, TNF-α, IL-4, IL-5, IL-10, IL-12, IFN-γ, löslicher IL-2- [r] ...
158
Curcumin and piperine supplementation of obese mice under caloric restriction modulates body fat and interleukin-1β
... lower IL-1β and KC/GRO concentrations in plasma compared to HFD ad ...(IFN-γ, IL-10, IL-12 p70 and IL-6) were not affected by including CR, CUR and Pip in the HFD, which ...
9
IL 17 produced by neutrophils regulates IFN γ–mediated neutrophil migration in mouse kidney ischemia reperfusion injury
... The IL-23/IL-17 and IL-12/IFN-g cytokine pathways have a role in chronic autoimmunity, which is considered mainly a dysfunction of adaptive ...of IL-23 and IL-12 ...
13
Role of osteopontin in amplification and perpetuation of rheumatoid synovitis
... of IL-10, TNF-α, and IFN-γ, while the production of IL-18 and IL-12 is not confined to rheumatoid synovium, as they are also detected at similar concentrations in paired ...
9
Immunological Study for the Role of Probiotic for Control on the Leishmania donovani
... as IL-12 and IFN- γ thus several studies confirm important of TLR signaling in the onset of the leishmanial pathogensis, susceptibility and resistance ...
9
Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys
... CRSsNP. IL-5, IL-10, IL-12, IL-17, and IFN-γ represent a disequilibrium of T cells in NP, and ECP, tryptase, G-CSF, MCP-1, MIP-1α, and MIP-1β depict the activation of ...
9
Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD
... and IL-1 that protect against tissue ...feron- γ (IFN- γ ), a "master" cytokine that orchestrates the coordinated induction and production of the "killing" phase ...as ...
12