IGFBP-3/IGF-1
Serum IGF-1, IGFBP-3 and their ratio: Potential biochemical growth maturity indicators
... serum IGFBP-3 were lowest at CVMI1 stage of cervical development with mean values of 3056 ± ...(Table 1). Thereafter, serum IGFBP-3 levels showed a sharp rise from CVMI2 o CVMI3 with a ...
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Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer
... of IGF- 1, IGFBP-3, and IGFBP-7 in serum and lung tissues may play an important role in the development of lung ...of IGF-1, IGFBP-3, and IGFBP-7 in ...
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Original Article IGF-1 and IGFBP-3 polymorphisms predict risk for non-traumatic osteonecrosis of the femoral head
... between IGF-1 rs2946834 TT/CT+TT genotype and baseline characteristics of NONFH showed that carrier with CT+TT genotype were associ- ated with a decreased disease severity, which further confirmed the ...
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Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls
... Subjects’ demographics and characteristics data were represented as mean ± standard deviations (SD). The height, weight, and BMI values were used to calculate the z-scores with the WHO Child Growth Standards for subjects ...
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Investigation of insulin like growth factors/insulin like growth factor binding proteins regulation in metabolic syndrome patients
... of IGFBP-2, IGFBP-1, IGFBP-3, IGF-1, and IGF-2 in diabetic patients who were assigned to two groups: MSx diabetic and non-MSx diabetic ...of IGFBP-2 compared ...
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The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study
... MMP-13, IGF-1, and IGFBP-3 and tumor recurrence, metastasis, or prognosis, the serum concentrations were divided into two ...an IGF-1 serum value ,130 ng/mL showed a significant ...
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Effect of zinc supplementation on growth Hormone Insulin growth factor axis in short Egyptian children with zinc deficiency
... increased IGF-1 and IGFBP-3 in non- Zn-deficient children with idiopathic short ...of IGF-1 and ...of IGF-1 and GH receptor genes in the liver of growing rats ...in ...
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Elevations in growth hormone and glucagon-like peptide-2 levels on admission are associated with increased mortality in trauma patients
... GH, IGF-1, IGFBP-3, and GLP-2 were tracked in 36 burn and trauma patients over a 6 week period and compared with outcomes data (hospital days, ICU days, ventilator days, and ...
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Effects of Exogenous Growth Hormone on Growth Hormone Insulin Like Growth Factor Axis of Human Gastric Cancer Cell
... included IGFBP-1, 2, 3, 4, 5, 6 and them were separated and were identified, and IGFBP-3 was re- garded as the major binding ...cases, IGFBP-3 could increase the ...
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Thyroid function in children with growth hormone (GH) deficiency during the initial phase of GH replacement therapy - clinical implications
... of IGF-I in stimulating that process has been suggested by Jørgensen et ...GH, IGF-I and thyroid hormone secretion have been subject of numerous .... IGF-I) concentrations were dimin- ished in ...
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An “Abundance” Phenotype Hypothesis for Autism
... BDNF, IGF-1, IGF-2, IGFBP- 3, GHBP, leptin, testosterone, oxytocin) and some autism risk factors (such as maternal metabolic conditions, prenatal and postnatal nutritional supplements, ...
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The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease
... and IGFBP-3 (100 ng/ml), as designated in the figure, for 48 ...but IGF-1 restored the level of Ser9 phosphorylation (a and b, p < ...into 1(b). IGFBP-3 precluded ...
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Combined sprint and resistance training abrogates age differences in somatotropic hormones
... respectively. IGF-1 was measured using the non-extraction IGF-1 immunoradiometric assay (IRMA) kit (Diagnostic Systems Laboratories, Webster, TX, ...respectively. IGFBP-3 ...
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<p>The relationship between serum-free insulin-like growth factor-1 and metabolic syndrome in school adolescents of northeast China</p>
... of IGF-1, IGFBP-3, fasting plasma glucose (FPG), fasting insulin (FINS), low-density lipoprotein choles- terol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), and ...
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Activation of Various Downstream Signaling Molecules by IGFBP 3
... to IGF-I and form a binary complex with IGF-I and prevent it to activate (IGF-IR) IGF-1 receptor (Figure 2) to stimulate cell proliferation and survival [27] ...[29]. ...
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Acute effects of physical exercise on the serum insulin like growth factor system in women with fibromyalgia
... free IGF-,1 IGF-2 and six binding proteins (IGFBP) of which IGF-1 and IGFBP-3 are most important in the skel- etal muscle [11] with positive outcomes of exercise ...
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Journal of Applied Pharmaceutical Science
... radiolabeled IGF-1 ...radiolegand IGF-1 and then detected with ...the IGFBP-1 (31 KDa), IGFBP-2 (36 KDa) and IGFBP-3 (45 ...mitogen IGF-1 ...
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Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease
... total IGF-1 was raised in late- onset, sporadic AD subjects as compared to ...the IGF-1:IGFBP-3 ratio, indicative of bioavailable IGF-1, was raised significantly in ...
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Genetic variants in insulin-like growth factor binding protein-3 are associated with prostate cancer susceptibility in Eastern Chinese Han men
... (PCa). IGF binding protein-3 (IGFBP-3) is an important member of the IGFBP family, which binds more than 90% of circulating IGF-1 with high affinity and specificity, and ...
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Effects of 8 Weeks of Resistance Training and IGF-1 Injection on Biochemical Markers of Cancer and Colorectal Structures in Rats
... high IGF-1 and low IGFBP-3 levels increase the risk of colorectal cancer and villous adenomas ...of IGF-1, IGFBP-3 and IGF-1/IGFBP-3 ...
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