IL-10-producing B cells
Original Article IL-10-producing B cells involved in the pathogenesis of Coxsackie virus B3-induced acute viral myocarditis
... of IL-10-producing splenic B cells was significantly elevated in CVB3-induced AVMC mice in both 1 w and 2 w ...of IL-10- producing B cells in 1 w AVMC ...
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Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of IL-10-producing B cells and reduced plasma cell infiltration of the joints
... splenocytes. IL-10-producing regula- tory B cells have been proposed to suppress pathogenic Th1/Th17 responses in CIA: interestingly therefore, although the levels of ...
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Original Article The different levels of IL-10-producing B cells, paralleling Th1 cells, between chronic myocarditis in cardiomyopathy induced by coxsackie virus B3
... with cells to detect the surface antigens for 30 minutes at 4°C. Cells, then were fixed and permeabi lized with a fixation/ permeabilization solution (BD Biosciences) for 20 minutes at ...maintain ...
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IL 10 is Predominantly Produced by CD19(low)CD5(+) Regulatory B Cell Subpopulation: Characterisation of CD19 (high) and CD19(low) Subpopulations of CD5(+) B cells
... CD19(+)CD5(+) B cells was investigated, by determining the expression levels of CD19, a classical B cell ...mononuclear cells were stained with fluorescence-conjugated anti-CD5, anti-CD19, ...
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Prevention of arthritis by interleukin 10-producing B cells
... by B cells. However, the fact that direct stimulation of purified B cells with antigen and anti-CD40 failed to trigger the differentiation of B cells into a regula- tory ...
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Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL 10–producing regulatory B cells
... T cells, macrophages, DCs, and epithelium ...mucosal IL-10–producing B cells, but not T ...mucosal IL-10–pro- ducing B cells in SPF-raised animals in ...
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B cell regulation of the anti-tumor response and role in carcinogenesis
... B10 B cells, IL-10 producing B cells; BCa, bladder cancer; BCDM, B cell deficient mice; Bregs, B regulatory cells; BTK, Bruton ’ s tyrosine kinase; ...
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Regulatory B Cells Are Inversely Associated with Disease Activity in Rheumatoid Arthritis
... T cells, together with increased levels of BAFF in active arthritis, comprise an inflammatory milieu in RA that favors the production of IL-10+ regulatory ...that IL-10 was increased ...
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Is there a feudal hierarchy amongst regulatory immune cells? More than just Tregs
... Traditionally, B cells have been seen as antibody secreting ‘machines’, but recently their capacity to produce distinct arrays of cytokines during chronic inflammation has been ...described B ...
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IL 10–producing NKT10 cells are a distinct regulatory invariant NKT cell subset
... iNKT cells display an increased frequency of pro- liferating ...iNKT cells have been shown to have a long-term reduction in proliferation and proinflammatory cytokine production upon antigen rechallenge (9, ...
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Suppression of antitumor immunity by IL 10 and TGF b producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells
... -secreting IL-10 and IFN- ␥ was examined by intracellular cytokine ...T cells resulted in a modest enhancement of the frequency of IFN- ␥ -secreting CD8 ⫹ T cells infiltrating the inguinal ...
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Mechanisms of allergen-specific immunotherapy
... memory cells takes ...Th2 cells, with the capability of producing IL-4 and IL-13, are essential in the induction of class switching to the ε immunoglobu- lin heavy chain in B ...
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Human regulatory B cells in health and disease: therapeutic potential
... of B cell depletion therapy ...all B cells to treat auto- immunity is disadvantageous, as it results in the depletion of Bregs that suppress ...effector B cell subsets depending on the disease ...
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IL 10 producing regulatory B cells (B10 cells) in autoimmune disease
... B10 cells can provide a new approach to the treatment of ...mature B cells while sparing B10/B10 PRO cells or the selective expansion of B10 ...PRO cells, it is currently impossible to ...
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Regulatory roles of IL 10 producing T follicular cells
... tissues, cells, molecules and chemical mediators that aim to recognize, neutralize and clear foreign ...immune cells, including myeloid cells, natural killer cells and innate lymphoid ...
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The anti-idiotypic antibody 1F7 stimulates monocyte interleukin-10 production and induces endotoxin tolerance
... B1 B cells ...B1 B cells, they may be activated either by direct interaction with HCV proteins or through interaction with other antibodies simulated by HCV ...B1 B cells ...
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Pathogenesis of Apical Periodontitis: a Literature Review
... T cells are able to regulate osteoclastogenesis by the RANKL and IFN-γ production ...T cells that has also been found to activate bone-resorbing cells ...precursor cells and, when activated, ...
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MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes
... T cells results in enhancement of the IL-6 + Th17 cell population, leading to insulin resistance and T2D in both human and ...T cells, leading to non-obese ...
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Alteration of T cell cytokine production in PLPp-139-151-induced EAE in SJL mice by an immunostimulatory CpG Oligonucleotide
... or relapse [6-9]. As a paradigmatic microbial stimulus simulating “infection” in our study CpG oligonucleotides were investigated regarding their co-stimulating effect on the PLPp-specific cytokine signature in PLPp- ...
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Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity
... that IL-10, produced mainly by renal-infiltrated Tregs and tolerogenic dendritic cells, efficiently reduced CDDP-induced AKI and associ- ated inflammation ...tration, IL-10 ...
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