IL-17 producing T cells
TLR4 mediates vaccine induced protective cellular immunity to Bordetella pertussis: role of IL 17 producing T cells
... of IL-17- producing T cells (Th-17), as well as Th1 ...Ag-specific IL-17 and IFN- ␥ production was significantly lower in Pw-immunized TLR4-defective ...dendritic ...
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A crucial role for IL 1 in the induction of IL 17 producing T cells that mediate autoimmune encephalomyelitis
... (IL)-23–driven IL-17–producing (ThIL-17) T cells mediate infl ammatory pathology in certain autoimmune ...ThIL-17 cells, but not T helper (Th)1 or Th2 ...
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IL-17 producing T cells correlate with polysensitization but not with bronchial hyperresponsiveness in patients with allergic rhinitis
... of IL-13 in mediating lower airway inflamma- tion and BHR following isolated allergic sensitization of the upper airways was suggested in a recent study of Wang et ...suggesting IL-17 contribution to ...
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MicroRNA 146a expresses in interleukin 17 producing T cells in rheumatoid arthritis patients
... with IL-17 producing T ...of IL-17 producing T cells is not simple, and perhaps they were depending on the disease variety, disease progression degree and ...
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Tissue specific CD4+ T cell priming determines the requirement for interleukin 23 in experimental arthritis
... heterodimeric IL-23 (p19/p40) is measured, very low levels are found despite high levels of the p19 subunit ...of IL- 23. An association of IL-23 levels in plasma with disease severity is shown in ...
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Intrinsic predisposition of naïve cystic fibrosis T cells to differentiate towards a Th17 phenotype
... CFTR-/- T cells, we postulated that an intrinsic predisposition to undergo Th17 differentiation should lead to the presence of an identifiable Th17 re- sponse in the peripheral blood of CF ...mononuclear ...
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IL 17/IL 10 double producing T cells: new link between infections, immunosuppression and acute myeloid leukemia
... leukemic cells via soluble factors through which Th17 are converted into IL-17/IL-10-secreting cells, creating an environment with reduced immune control and thus probably favoring ...
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Evaluation of IL-17 Producing Memory Regulatory and Effector T Cells Expressing CD26 Molecule in Patients with Psoriasis
... Regulatory T cells have an important role in maintaining self-tolerance and homeostatic immune ...these cells were detected with the CD4 + CD25 + phenotype, 9 but discovery of transcription factor ...
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Bilirubin suppresses Th17 immunity in colitis by upregulating CD39
... UCB ameliorates experimental colitis. Previous evidence had shown that UCB has immunomodulatory proper- ties in inflammatory conditions in vivo (2, 6). We tested the effect of UCB administration on DSS-induced colitis ...
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The attenuation of renal fibrosis by histone deacetylase inhibitors is associated with the plasticity of FOXP3+IL-17+ T cells
... into IL-17-producing cells in the presence of rhIL-2/rhIL-15 when stimulated by antigen presenting cells ...of IL- 17-producing cells from Tregs and that ...
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Rheumatoid arthritis bone marrow environment supports Th17 response
... of IL-15 in Th17 cell differentiation is not clearly defined. The IL-15 concentration is known to correlate with the concentration of IL-17 in synovial fluid from RA patients ...of ...
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Reduced Frequency of Memory T Cells and Increased Th17 Responses in Patients with Active Tuberculosis
... ⫹ T cells into the lungs (35, 36, 49, ...Th17 cells in later stages of the ...proposed. IL-17 has been implicated in induction and recruitment of neu- trophils into the lungs (47, 73) ...
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Development of interleukin-17-producing Vγ2 γδ T cells is reduced by ICOS signaling in the thymus
... killer T (NKT) cells and the recently discovered natural Th17 (nTh17) cells [26, ...Treg cells [28]. ICOS is expressed by γδ T cells [29] already in the thymus, but little is ...
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Decreased IL 17 during treatment of sputum smear positive pulmonary tuberculosis due to increased regulatory T cells and IL 10
... improvement. IL-17 levels and IL-17-producing cells in PBMCs were ...A549 cells, a cell line of alveolar epithelial cells, were applied to determine the extent of ...
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T cell receptor signaling for γδT cell development
... γδT cells, which have the inherent ability to produce cytokines such as interferon-γ (IFNγ) and interleukin-17 (IL-17), contribute to rapid immune responses against a broad spectrum of ...
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Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity
... that IL-10, produced mainly by renal-infiltrated Tregs and tolerogenic dendritic cells, efficiently reduced CDDP-induced AKI and associ- ated inflammation ...tration, IL-10 producing Tregs ...
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Human Th17 cells
... with IL-12 in these diseases was called into question by the discovery that a new IL-12 family member, namely IL-23, shares with IL-12 the p40 subunit, the heterodimer of IL-12 being ...
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Recurrent pseudogout after therapy with immune checkpoint inhibitors: a case report with immunoprofiling of synovial fluid at each flare
... + T cells in immune re- sponses, we focused on CD4 + T cells in synovial fluid ...+ T cell subsets in synovial samples revealed that the most abundant CD4 + T cell subset was ...
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Distribution, characterization, and induction of CD8+ regulatory T cells and IL 17 producing CD8+ T cells in nasopharyngeal carcinoma
... Tc17 cells expressed high levels of IL-17 and TNFa, intermediate levels of IL-10, and low levels of ...Tc17 cells in the TILs but not in the PBMCs of patients with NPC expressed high ...
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MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes
... Importantly, a clinical study of a consortium of 18,565 European normal-weight/overweight/obese individuals from eight European countries demonstrates that the association between insulin resistance and T2D incident is ...
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