IL-1α
RIPK3 expression in cervical cancer cells is required for PolyIC- induced necroptosis, IL-1α release, and efficient paracrine dendritic cell activation
... enhance IL-12 production in DC in the absence or presence of ...induce IL-12 release in DC when applied alone; however, it strongly enhanced PolyIC- mediated IL-12 release in DC (Figure ...endogenous ...
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The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles
... France). IL-1α-, IL-1β-, IL1-R1- and MyD88-competent and -deficient mice (in C57BL/6 background) were obtained from the Transg?nose Insti- tute (Orleans, ...
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IL 33 regulates the IgA microbiota axis to restrain IL 1α–dependent colitis and tumorigenesis
... of IL-1α, IL-33, ST2, and sST2 are increased in the mucosa of IBD patients, and SNPs in IL33 and ST2 are associated with the development of IBD ...exogenous IL-33 infusion have attributed the ...
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Role of Interleukin 1 Alpha (IL 1α) and Interleukin 1 Receptor Antagonist (IL 1RA) in Pathogenesis of Juvenile Idiopathic Arthritis and Adult Onset Rheumatoid Arthritis of Iraqi Patients
... of IL-1α in the pathogenesis of JIA was not well- defined in the present study, especially if we notice that its serum level in patients represented about 50% of IL-1α level in controls; ...
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Macrophage and neutrophil dominant arthritis in human IL 1α transgenic mice
... Generation of Tg mice. hIL-1 α cDNA (Immunex Co., Seat- tle, Washington, USA) was excised with HindIII and HincII (Roche Diagnostics, Mannheim, Germany). This 660 bp HindIII/HincII restriction fragment was inserted into ...
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Expression of IL-1α correlates with distant metastasis in patients with head and neck squamous cell carcinoma
... of IL-1α was categorized using a classification and regression tree (CART) method, considering the appearance of distant metastasis as the dependent ...of IL-1α as defined by ...
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The Effect of Ginger Supplementation and EnduranceTraining on Serum Levels of IL-1α and TNF-α
... that IL-1α decreased significantly in the EG and G groups, while TNFα decreased significantly in the E, EG and G ...and IL-1-α in skeletal muscles of young ...and IL-6 ...
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IL 1α, IL 1β, and IFN γ mark β cells for Fas dependent destruction by diabetogenic CD4+ T lymphocytes
... as IL-1α, IL-1β, and TNF — do not develop diabetes (42, ...(IL-1α, IL-1β, and IFN-γ) prime NOD β cells for Fas-dependent lysis in ...
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The impact of IL1A SNP at -889 position on IL-1α serum level in multiple sclerosis Iraqi patients
... of IL-1α in pre-medicated MS patients compared to post-medicated patients and controls, and the difference between the three groups was also significant ...of IL-1α compared to post-medicated ...
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Original Article Polymorphisms of IL-1β and IL-1α genes and susceptibility to low back pain: a systematic review and meta-analysis
... accord with the reports of Karppinen, J et al. [15] and Solovieva, S et al. [10]. Correspondingly, Schistad et al. [28] had reported that CT/TT genotype IL-1α (+889 C/T) might be associated with elevated ...
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Original Article Association of IL-1α, IL-1β, IL-18 and IL-33 genetic variants with the risk of Alzheimer disease in a Chinese population
... One limitation should be pay attention to. The investigated subjects were recruited from only one place and hospital in China. This would not be sufficiently representative of other popula- tions and cause selection bias ...
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IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice
... of IL-1α (Figure 4F), although not in a complete ...abrogated IL-1α release in LPS-treated lung TAMs, implying a cross-talk between caspase-1 and ...of IL-1α when LPS was added ...
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Original Article Ovarian IL-1α and IL-1β levels are associated with primary ovarian insufficiency
... production IL-1α and IL-1β in ovarian follicles of POI patients ...that IL-1 levels in fol- licular fluids and serial samples of POI patients are significant higher than healthy ...which ...
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Endogenous IL 1α from systemic sclerosis fibroblasts induces IL 6 and PDGF A
... of IL-6 response in SSc-affected fibroblasts. IL-1α was shown to modulate the mitogenic response of normal fibroblasts, and the mitogenic action was indirect and mediated by the induction of PDGF-A ...
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Antipsoriatic and Inhibitory effects of an oral dosage form containing Bioflavonoids on inflammatory cytokines IL-1α, IL-1β, IL-6, IL-8, IL-17 and TNF-α
... plemented RPMI-1640 media at a concentration of 3 µg/ml. The test sample was dissolved in DMSO at concentrations of 1, 3, 10, and 30 µg/ml and each of these concentrations was diluted with the supplemented RPMI-1640 ...
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Evaluation of pro-inflammatory and anti-inflammatory cytokines in type 1 diabetes mellitus
... of T-lymphocyte functions, production of inflammatory cy- tokines, and T1DM progression (Tchorzewski et al. 2001). In T1DM, cells enhancing native and adaptive immunity infiltrate pancreatic islets, thus producing an ...
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Expression of Pro-inflammatory Genes in Lesions and Neutrophils during Leishmania major Infection in BALB/c Mice
... TNF-α, IL-1α, IL-12P35, IL-12P40, CCL5, CCR5, IL-1β and IFN- γ and their expression were assessed and compared using RT-PCR in the le- sion and peripheral blood neutrophils in ...
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Redefining the ancestral origins of the interleukin 1 superfamily
... four IL-1 family clusters to create a more realistic IL-1 ligand superfamily tree that better reflects the uncertain evolutionary history of protein/gene families, despite the inherently weak phylogenetic ...
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COMPARISON OF PATHOGENESIS OF P. BERGHEI INFECTION IN MOUSE AND RAT MODELS
... of IL-10 expression in the severe model was insufficient to counter the high levels of circulating TNF-α, IFNγ and IL-1α, which resulted in high mortality in the ...
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Text 1 Abstrak pdf
... seperti IL 1α, IL 6, IL 8, TGF 1β dan TNF α yang akan berperan dalam proses inflamasi pada epitel permukaan ...sitokin IL 6, IL 8 dapat meningkatkan pertumbuhan sel epitel ...
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