IL-1β/IL-18
Original Article Association of IL-1α, IL-1β, IL-18 and IL-33 genetic variants with the risk of Alzheimer disease in a Chinese population
... interleukin-1, IL-8, IL-6 and tumor necrosis factor-α (TNF-α) and ...15]. IL-1 is an important inflammatory cytokines for inducing inflammatory response and the defense response ...[1]. IL-1 ...
8
Original Article Resveratrol inhibits IL-1β, IL-18, and ICAM-1 in a nasopharyngeal carcinoma model
... In this experiment, a nude mice model of naso- pharyngeal carcinoma was established, exam- ining the effects of RES on IL-1β, IL-18, and ICAM-1 in nasopharyngeal carcinoma. There were some ...
8
Original Article Serum level of IL-1β and IL-18 in patients with traumatic brain injury and their effects on cognitive impairment
... of IL-1β and IL-18 were obviously increased in patients undergoing ...of IL-1β and IL-18 were ...with IL-1β and IL-18 serum ...cytokines ...
7
Original Article Correlation between inflammatory markers (hs-CRP, TNF-α, IL-1β, IL-6, IL-18), glucose intolerance, and gestational diabetes mellitus in pregnant women
... TNF-α, IL-1β, total cholesterol, HDL- cholesterol, and LDL-cholesterol had no obvi- ous difference among the three groups (P > ...hs-CRP, IL-6, IL-18, HbA1c, insulin, triglyc- ...
7
Hepatitis C Virus Induces Interleukin-1β (IL-1β)/IL-18 in Circulatory and Resident Liver Macrophages
... of IL-1  / IL-18 in the THP-1 cell line as well as in primary human macro- phages and Kupffer ...of IL-1  /IL-18 from infected Huh7 ...of IL-1  ...induce IL-1  ...
7
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β
... Pyrin was the first protein implicated in autoinflammatory disease due to mutations that activate the innate immune sys- tem in FMF (The International FMF Consortium, 1997). Subsequent work showed that this protein ...
13
Interleukin 37 is increased in adult onset Still’s disease and associated with disease activity
... The IL-37 expression level was markedly upregulated in peripheral blood monocular cells (PBMCs), epithelial cells, macrophages, dendritic cells (DCs), and T cells following the stimulation of proin- flammatory ...
12
Download Download PDF
... of IL-6 in the CSF, and IL-1β, IL-18 and TNF-α in the serum samples were observed in the children with Stage II HIE, in general, we did not observe sig- nificantly higher concentrations ...
8
IRS as well as the compensatory immune regulatory system CIRS Treatment with sertraline significantly increased zinc and decreased copper levels, while
... MyBioSource ® Inc., USA, while IL-1β, IL-6, and IL-18 ELISA kits were supplied by BioAssay Systems ® , USA. All kits were based on a sandwich technique and showed an inter-assay CV less ...
35
Glial contributions to neurodegeneration in tauopathies
... (TNF-α), IL-6, IL-18 and interferon gamma (IFN-γ) as well as pro- duce nitric oxide, reactive oxygen species and many others associated with a neurodegenerative phenotype ...like IL-4, ...
16
Redefining the ancestral origins of the interleukin 1 superfamily
... four IL-1 family clusters to create a more realistic IL-1 ligand superfamily tree that better reflects the uncertain evolutionary history of protein/gene families, despite the inherently weak phylogenetic ...
12
Antidiabetic efficacy of lactoferrin in type 2 diabetic pediatrics; controlling impact on PPAR-γ, SIRT-1, and TLR4 downstream signaling pathway
... (IL-1β, IL-6, IL-18), Cyclin D-1, lipocalin-2, and PPAR-γ expression levels were done at the beginning and 3 months after daily consumption of ...of IL-1β, IL-6, ...
12
Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation
... Sterile inflammatory insults due to cyclic or chronic hypoxic conditions within solid tumors initiate an influx of myeloid cells (e.g., monocytes and macrophages) [8]. Myeloid and epithelial cells express cytosolic DNA ...
12
Activation of inflammasome signaling mediates pathology of acute P aeruginosa pneumonia
... of IL-1β and IL-18 is responsible for a substantial amount of the pathology associated with acute ...Caspase-1, IL-1R, and IL-18R are potential targets to limit pathologic ...
9
TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies
... and IL-1β have been shown to strongly syn- ergize in numerous biological functions, both in vitro and in vivo ...induce IL-1β in human ...and IL-1β secretion in murine ...
11
Helicobacter urease–induced activation of the TLR2/NLRP3/IL 18 axis protects against asthma
... for IL-1β ELISA as a screening readout (Supplemental Figure ...inducing IL-1β secretion (<25% of the corresponding WT infection) were sequenced and mapped to 32 different loci (Supplemental ...
7
Autophagy controls IL 1? secretion by targeting pro IL 1? for degradation
... and IL-1β secretion in embryonic liver macrophages from Atg16L -/- mice, suggesting a role for autophagy in dampening the inflammatory response to endotoxin ...of IL-1β, while cells treated ...
20
Original Article Expression of IL-2, IL-6, IL-10, and IL-1β in rats with fungal keratitis
... that IL-6 plays an extremely important defensive role in anti-fun- gal infection ...that IL-6 was hardly expressed in the blank control group, but began to increase in the fungal experimental group and ...
8
The Correlation Between IL-1β and IL-10 Levels in Estimating The Risk of Febrile Seizures
... that IL- 10 febrile seizure levels were significantly higher than those for control, but used short stature patients with-out fever, anemia, constipation and growth failure as controls ...that IL-10 levels ...
6
Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection
... defective IL-1R/TLR signaling ...or IL-17 responses (i.e., autosomal dominant hyper-IgE syndrome and IL-17F or IL-17Ra deficiency; ...of IL-1β/IL-1R1/MyD88 signaling (13, ...
18