immature dendritic cell
Pre immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer
... Patients were assigned to two arms. Arm A received HPV16 E6 (18–26) peptide, while patients on arm B received HPV16 E7 (12–20) peptide pulsed on pre- immature dendritic cells (PIDCs). Patients had ...
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Subviral Dense Bodies of Human Cytomegalovirus Stimulate Maturation and Activation of Monocyte-Derived Immature Dendritic Cells
... Having shown that DB treatment leads to maturation and activation of DC, we next tested if this resulted in an enhanced capacity of these cells to present antigen and to stimulate au- tologous T cells in IFN-␥ ...
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MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells
... cells reached 90% confluence, the original media were removed and the monolayer cells were washed with PBS once. Approximately 1 × 10 6 of RD cells were in- cubated with EV71 strain GDV083 (ATCC VR-784) at a MOI of 5 or ...
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Human Immunodeficiency Virus Type 1 Replication in Dendritic Cell-T-Cell Cocultures Is Increased upon Incorporation of Host LFA-1 due to Higher Levels of Virus Production in Immature Dendritic Cells
... host cell membrane constituents, including the adhesion glycoproteins ICAM-1 and ...in immature monocyte-derived DC (IM-MDDC)–T-cell cocultures when LFA-1-bearing virions are used for ...
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Human Immunodeficiency Virus Type 1 Derived from Cocultures of Immature Dendritic Cells with Autologous T Cells Carries T-Cell-Specific Molecules on Its Surface and Is Highly Infectious
... Results obtained by VCA revealed that HIV-1 which bud- ded from DC or T cells was coated with a host-cell-specific spectrum of surface molecules. In contrast, HIV-1 derived from DC–T-cell cocultures ...
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Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4+IL17+ response
... patient immature dendritic cells were suspended in 1 ml of AIM V media (Life Tech- nologies) and pulsed with 10 μg of tumor lysate derived from the vaccine cell line and maturated with human ...
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Leishmaniasis in humans: drug or vaccine therapy?
... FML-QS21 indicate that bradykinin activity could medi- ate inflammatory responses at the site of injection which stimulate immature dendritic cells, and consequently, this[r] ...
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Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein
... the cell surface of immature dendritic cells, was found to be essential for productive infection (39, ...virion. Immature dendritic cells have been proposed to be the primary target ...
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Investigations of the functional states of dendritic cells under different conditioned microenvironments by Fourier transformed infrared spectroscopy
... The immature dendritic cells and mature dendritic cells were induced by traditional ...resulting dendritic cells were cocultured with normal cells and cancer ...of dendritic cells ...
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Influence of synthetic superparamagnetic iron oxide on dendritic cells
... for dendritic cells (Figure 3). To determine whether dendritic cell surfaces would be influenced by SPIO labeling, an immunostaining assay was performed with a panel of antibodies against the ...
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Comparison of immature and mature bone marrow derived dendritic cells by atomic force microscopy
... resolutions, cell height profile and histogram, topography, and roughness on the surface of the cells (Figure ...The immature BMDCs treated with rmGM-CSF plus rmIL-4 were shown on Fig- ure 3A-3G, and the ...
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Dynamic interactions between T cells and dendritic cells and their derived cytokines/chemokines in the rheumatoid synovium
... This review focuses on the contributions made by interactions between dendritic cells (DCs) and T cells, and by local production of cytokines and chemokines to the pathogenesis of rheumatoid arthritis (RA) ...
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Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells
... helper cell and deleterious IgE mediated immune ...mainly dendritic cells (DCs), leading to Th2 polarization, switch- ing to IgE production by B cells, culminating in mast cell sensitization and ...
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Schnorfeil, Frauke Marie (2011): MicroRNAs regulate Dendritic Cell Development and Function. Dissertation, LMU München: Medizinische Fakultät
... While pDCs and cDCs share common progenitors (section 4.1.2), pDCs possess distinct mo- lecular features resembling those of lymphocytes. pDCs are also called natural interferon- producing cells, as they produce massive ...
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Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice
... Histone deacetylase inhibitors (HDAi), such as trichostatin A (TSA) and suberoylanilide hydroximic acid, are small molecule compounds that exert anti- proliferative effects on various tumor cells and are cur- rently used ...
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DNA methylation dynamics during ex vivo differentiation and maturation of human dendritic cells
... monocyte-derived dendritic cells (iDCs), and DCs matured by Jonuleit cocktail ...for dendritic cell lineage ...in dendritic cell func- tion, our analysis also revealed many novel ...
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Deficient Natural Killer Dendritic Cell Responses Underlay the Induction of Theiler's Virus Induced Autoimmunity
... In SJL/J mice, infection with TMEV results in a chronic infec- tion of the central nervous system (CNS). The establishment of chronic infection is a prerequisite for the transition from an im- mune response that is ...
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Dendritic Cell Autophagy Contributes to Herpes Simplex Virus Driven Stromal Keratitis and Immunopathology
... To test this, we evaluated immune infiltration into corneas at 14 dpi and 38 dpi using flow cytometry (Fig. 5). Although no differ- ences in the relative proportions of the analyzed cells infiltrating the cornea were ...
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Original Article Immature CD11c+ myeloid dendritic cells with inflammatory and regulatory cytokine profile in human seminoma
... that immature CD1a+ and DC-SIGN+ DCs playing a pivotal role in the capture of auto antigens or exogenous antigens and subsequent processing for pre- sentation to T lymphocyte [28, ...the immature marker and ...
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A role for pre-mNK cells in tumor progression
... by dendritic cells ...immune cell qualities, termed interferon-producing killer dendritic cells ...NK cell attributes than DC but purportedly can regulate the immune system similar to ...
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