Immediate Early Genes
Echovirus 1 replication, not only virus binding to its receptor, VLA-2, is required for the induction of cellular immediate-early genes.
... of immediate-early genes c-jun, junB, and c-fos was demonstrated during echovirus 1 infection in a human osteogenic sarcoma (HOS) cell ...activating immediate-early ...the ...
5
The immediate early genes of human cytomegalovirus upregulate tumor necrosis factor alpha gene expression
... CMV immediate early (IE) gene region are potent trans- activators, we used the monocyte cell line THP-1 and a transient transfection assay to determine if these viral proteins upregulate expression of the ...
6
Effect of a modulator deletion on transcription of the human cytomegalovirus major immediate-early genes in infected undifferentiated and differentiated cells.
... (SV40) early promoter ( 2 138/ 1 57) of plasmid pGL-promoter (Pro- mega) and a HindIII-BamHI fragment of pMSG (Pharmacia, Piscataway, ...SV40 early splice region, and SV40 early polyadenylation ...
10
Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus
... 2 genes, when compared to cells transfected with a control ...HCMV genes only ...IE genes on cell-derived genes, such as the IL-1 beta ...
6
Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate Early Genes
... promoters early in infection, we hypothesized that the two phenotypes might be ...ICP27 genes, to which the Oct-1/HCF-1/VP16 complex is known to bind ...E genes lack VP16 binding ...
11
Allogeneic Transplantation Induces Expression of Cytomegalovirus Immediate-Early Genes In Vivo: a Model for Reactivation from Latency
... MCMV immediate-early pro- tein-1 (IE1) transcripts are not detectable in tissues of latently infected mice (34), while others have reported that they are detectable in some organs (5, 30, 37, 77, ...
9
Constitutive and retinoic acid-inducible expression of cytomegalovirus immediate-early genes in human teratocarcinoma cells.
... We show that in uninduced teratocarcinoma stem cells, and also in transformed human 293 cells expressing adenovirus Ela gene products, the HCMV immediate-early IE 68,000-molecular-weight[r] ...
7
Cytomegalovirus immediate early genes prevent the inhibitory effect of cyclosporin A on interleukin 2 gene transcription
... (CMV) immediate early (IE) gene products on interleukin 2 (IL-2) gene transcription in the absence and presence of CsA was investigated using a transient transfection ...
6
Immediate-early genes of murine cytomegalovirus: location, transcripts, and translation products.
... 526 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Cloned genomic fragments from the region 0.769 to 0.818 map units coding for immediate-early IE transcripts of murin[r] ...
8
Neurotrophins, immediate early genes and neuronal cell death
... rly genes (lEGs) o f the fos and ju n fam ilies, could pro vid e im p o rta n t clues as to the relevance o f e ith e r o f the above models to the phenomenon o f selective neuronal cell ...
200
Acid activation of immediate early genes in renal epithelial cells
... IE genes by a different mechanism in that the increase in mRNA did not include c-jun, was more prolonged, and was blocked by ...IE genes that is similar to growth factor-induced IE gene activation, and is ...
8
Characterization of the major locus of immediate-early genes of rat cytomegalovirus.
... In contrast to the lack of homology seen among the IE1 proteins, extensive homology was found across exon 5 of RCMV, MCMV, and HCMV IE2 predicted amino acid sequences, with three conserv[r] ...
11
Organization and expression of the immediate early genes of human cytomegalovirus.
... Since immediate early gene expression of human cytomegalovirus is dominated by the synthesis of an mRNA from the region of 0.739 to 0.751 map units that codes for the predominant immedia[r] ...
14
Genome-Wide Histone Acetylation Profiling of Herpesvirus saimiri in Human T Cells upon Induction with a Histone Deacetylase Inhibitor
... viral genes during ...only genes with considerable levels of expression/transcription, and they show a corresponding active chromatin ...of early lytic ...lytic genes, reveals the activities ...
9
Methylation of the promoter for an immediate-early frog virus 3 gene does not inhibit transcription.
... Since FV3 immediate-early genes are transcribed in the absence of de novo protein synthesis, it appears that the virus-induced trans-acting protein that allows transcription from methyla[r] ...
6
Epstein-Barr Virus MicroRNA miR-BART20-5p Suppresses Lytic Induction by Inhibiting BAD-Mediated caspase-3-Dependent Apoptosis
... BZLF1 in the context of miR-BART20-5p function was investi- gated. We found that miR-BART20-5p inhibited the expression of EBV immediate early genes indirectly by suppressing BAD-in- duced ...
10
Induction patterns of 70 genes during nine days after hepatectomy define the temporal course of liver regeneration
... 70 immediate-early genes induced in regenerating liver after hepatectomy, 41 of which were ...these genes may have important roles in regulating progression through the G1 phase of the cell ...
9
Biphasic induction of immediate early gene expression accompanies activity dependent angiogenesis and myofiber remodeling of rabbit skeletal muscle
... of immediate early genes such as c-fos, c-jun, and egr-1 function in many signaling pathways governing cellular responses to external stimuli, we sought to determine whether sustained contractile ...
10
trans activation of an immediate-early frog virus 3 promoter by a virion protein.
... The immediate-early genes are transcribed from parent templates even in the presence of cycloheximide; the lack of a requirement for de novo protein synthesis indicates either that this [r] ...
7
Amphetamine manipulates monoamine oxidase-A level and behavior using theranostic aptamers of transcription factors AP-1/NF-kB
... Amphetamine exposure induces elevations in immediate early genes and their products; however, the relationship of such changes in gene expression to amphetamine in- duced restless activi[r] ...
8