immune regulation
Human allograft acceptance is associated with immune regulation
... A different pattern of immune regulation was observed when PBMCs from patient A.J. were tested in the trans vivo DTH assay. Patient A.J. is a diabetic 57- year-old male who received a six-HLA antigen–mis- ...
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Immune regulation in IgA nephropathy
... in immune regulation Dendritic cells (DC) are professional antigen presenting cells that play a critical role in the initiation and regulation of immune responses ...induce immune ...
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Achieving antigen specific immune regulation
... for immune modulation, but an important, as-yet-unanswered ques- tion has been whether the regulatory cells are antigen specific and how specificity is ...nonspecific immune suppres- sion would be as ...
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Plasticity of Mesenchymal Stem Cells based on Immune Regulation Network
... Mesenchymal stem cells (MSCs), a pluripotent stem cell, were first discovered in the bone marrow stroma in the 1860s and were later defined as "colony-forming unit fibroblast" [1] . At present, it is found that ...
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Immune Regulation of Plasmodium Is Anopheles Species Specific and Infection Intensity Dependent
... We found that silencing any of the three genes in the vector-parasite combination involving sympatric species, the A. gambiae-P. falciparum NF54 strain combination, did not affect the infection intensity or prevalence, ...
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Microbiota control immune regulation in humanized mice
... Immune cell phenotypes. Cells were isolated from spleen, peripheral blood, and mesenteric lymph node following tissue homogenization. RBCs in peripheral blood and spleen were lysed using ACK lysis buffer (Lonza). ...
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Immune regulation of bone loss by Th17 cells
... Th17 cells are a newly discovered T-cell lineage that plays a role in the adaptive immune response to extracellular patho- gens. The repertoire of molecules at its disposal to combat these pathogens is formidable. ...
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Expression of the immune regulation antigen CD70 in osteosarcoma
... CD70 protein was expressed on most osteosarcoma cell lines (5/7) and patient-derived primary osteosarcoma cultures (4/6) as measured by flow cytometry. In contrast, CD70 was detected on few Ewing sarcoma cell lines ...
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Systematic evaluation of immune regulation and modulation
... of immune-related biomarkers for diagnosis, prognosis, monitoring of immune responses and identifi- cation of their mechanism of action, as well as for the se- lection of patients undergoing cancer ...
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Immunosuppressive Drugs and Immune Regulation in Organ Transplantation
... donor-directed immune responses by Teff cells is signifi cantly lower than the third party immune responses after coculture with Treg post-transplant in the suppression ...The immune system adapts to ...
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Clinical efficacy and immune regulation with peanut.pdf
... 7242 // intracellular signaling cascade // inferred from electronic annotation /// 7242 // intracellular signaling cascade // non-traceable author statement /// 8286 // insulin receptor [r] ...
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Metabolic regulation of immune responses: therapeutic opportunities
... metabolic enzymes can bind to mRNA, including those involved in glycolysis, the KREBS cycle, and fatty acid synthesis (99). How- ever, the exact mRNA transcripts involved have not been iden- tified and the significance ...
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Regulation of chronic inflammatory and immune processes by extracellular vesicles
... to immune regulation. EVs derived from both immune and nonimmune cells carry self antigens following infection by pathogens and other foreign anti- ...modulate immune responses, serving to ...
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Initiation and Regulation of CNS Autoimmunity: Balancing Immune Surveillance and Inflammation in the CNS
... The “oldest” APCs that were proposed to contribute to CNS immunity were the microglia and were first de- scribed by Pio del Rio-Hortega (reviewed in [61]). Mi- croglia are abundant everywhere in the CNS [61] and are ...
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Regulation of autoreactive B cells during innate immune responses
... significant differences in ERK activation by IL-6R and CD40 signaling, despite the increased expression of CD40 on 2-12H/Vκ8 B cells. Next we examined the duration of IL-6/sCD40L-induced ERK activation in ...
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Regulation of DNA-Raised Immune Responses by Cotransfected Interferon Regulatory Factors
... Interferon regulatory factor 1 (IRF-1), IRF-3, and IRF-7 have been tested as genetic adjuvants for influenza virus hemagglutinin (HA) and nucleoprotein vaccine DNAs. Cotransfection of HA with IRF-3 and IRF-7 increased ...
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Cancer therapeutic implications of microRNAs in the regulation of immune checkpoint blockade
... of immune checkpoints can be secreted by exosomes to effect on other ...regulate immune checkpoints as ...the regulation of immune checkpoint blockade is necessary to complete the regulatory ...
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Immune System Regulation With Cancer Vaccines Based on Dendritic Cells
... The immune system utilizing some cytotoxic molecules like perforin to kill the cancer cells and also inducing expression of TNF related apoptosis-inducing ligand (TRAIL) on immune cells primarily NK cells, ...
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Cytokine regulation of immune tolerance
... It is well-recognized that not all self-reactive T cells are eliminated in the thymus. A traditional viewpoint suggests that peripheral tolerogenic mechanisms (e.g., T cell anergy, exhaustion, deletion, or Treg ...
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Regulation of an essential innate immune response by the p50 subunit of NF kappaB
... ure (1). Infection with Gram-negative bacteria is a leading cause of such problems. This group of pathogens contains a membrane glycolipid known as endotoxin (LPS). LPS acti- vates cells of the innate immune ...
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