Immunoglobulin G/A
Antitumor activity of a folate receptor-targeted immunoglobulin G-doxorubicin conjugate
... In this study, we designed and synthesized a novel ADC drug, folate-polyethylene glycol-immunoglobulin G-doxorubicin (FA-PEG-IgG-DOX). In this conjugate, FA-PEG-IgG was designed as a FR-targeting antibody ...
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A novel immunoglobulin G monolayer silver bio-nanocomposite
... applications. Immunoglobulin G (IgG) molecule was chosen for the passivation of the silver nanoparticles (AgNPs) in order to avoid macrophage recognition of the synthesized ...
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Accelerated breakdown of immunoglobulin G (IgG) in myotonic dystrophy: a hereditary error of immunoglobulin catabolism
... Thus, the defective metabolism observed in myotonic dystrophy does not represent an actual loss of plasma proteins from the body, but rather appears to be an endogenous defect of catabol[r] ...
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Expansion of Fc receptor bearing T lymphocytes in patients with immunoglobulin G and immunoglobulin A myeloma
... Lymphocytes obtained from the blood of normal individuals and six patients with newly diagnosed multiple myeloma were separated into T and non-T cell populations by rosetteformation with[r] ...
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Immunoglobulin G is a platelet alpha granule secreted protein
... In these studies, the location of IgG within human platelets was investigated by immunocytochemical techniques and by the response of platelet IgG to agents that cause platelet secretion[r] ...
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Immunoglobulin G and immunoglobulin M polar staining of Toxoplasma gondii in the indirect immunofluorescence test
... Polar staining PS of Toxoplasma gondii in the indirect immunofluorescence IIF test has been described as a nonspecific reaction confined to the anterior pole of the protozoan and is pres[r] ...
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Vol 29, No 2 (2019)
... A relationship appears to exist between immunoglobulins and keloid formation; while levels of immunoglobulin G and immunoglobulin M are normal in the serum of patient[r] ...
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Application of enhanced electronegative multimodal chromatography as the primary capture step for immunoglobulin G purification
... recombinant immunoglobulin G monoclonal antibodies (IgG mAbs) produced in Chinese hamster ovary (CHO) cells are usu- ally achieved by 3–4 successive chromatographic steps (Girard et ...
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Clinical Severity of Visceral Leishmaniasis Is Associated with Changes in Immunoglobulin G Fc N Glycosylation
... and immunoglobulin classes and subclasses, interactions of IgG molecules with cellular receptors or the complement-activating protein mannan-binding lectin (MBL) are regulated by the nature of N-linked, ...
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Determining the IgG concentrations in bovine colostrum and calf sera with a novel enzymatic assay
... inadequate immunoglobulin concentration contributes to failed transfer of passive immunity in calves, leading to higher calf morbidity and ...measure immunoglobulin content in colostrum or ...trehalase ...
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Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae
... Blocking immunoglobulin G (IgG) inhibits complement-mediated killing of serum-resistant Neisseria gonorrhoeae (GC) in immune human serum. We examined the mechanism of action of blocking IgG. ...
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Function and heterogeneity of human Fc receptors for immunoglobulin G
... huFcRI HuFc7RI, found predominantly on monocytes and macrophages, binds monomeric human IgG with high avidity Ka = 1-3 X 108 M-' and with a subclass specificity of IgGl > IgG3 > IgG4 > I[r] ...
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In Situ Hybridization Detection of Human Herpesvirus 6 in Brain Tissue From Fatal Encephalitis
... HHV-6, human herpesvirus 6; ISH, in situ hybridization; CSF, cerebrospinal fluid; IgG, immunoglobulin G; IgA, immunoglobulin A; IgM, immunoglobulin M; PCR, polymer- ase chain reaction; H[r] ...
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Solid phase radioimmunoassay of rubella virus immunoglobulin G and immunoglobulin M antibodies
... Balls adsorbed at each rubella virus protein concentration were incubated with dilutions of a rubella antibody-positive serum and tested for binding of rubella-specific IgG antibodies up[r] ...
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Neutrophil binding immunoglobulin G in systemic lupus erythematosus
... antibodies to the levels of IgG neutrophil-binding activity in SLE sera. Neutrophil-bound IgG, determined by a sensitive antiglobulin inhibition assay, was elevated in 7 out of 14 SLE patients compared with values ...
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Guillain Barre syndrome presenting with sensory disturbance following a herpes virus infection: a case report
... Two lumbar punctures were performed, the first on admittance and the second 14 days following com- mencement of the symptoms (Table 1). The diagnostic tests are summarized chronologically in Table 2. Serol- ogy tests for ...
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Serological screening of immunoglobulin M and immunoglobulin G during pregnancy for predicting congenital cytomegalovirus infection
... for immunoglobulin (Ig) M is difficult to diagnose as primary infection, because CMV IgM persists for a long time (> 5 months to over 1 year) after infection in some individuals (known as “persistent IgM”) [11, ...
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Levels of Immunoglobulin Classes Are Not Associated with Severity of HIV Infection in Nigerian Patients
... of immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), total pro- tein and albumin were measured in 35 Human Immunodeficiency Virus—positive, HAART (highly active ...
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Piezoelectric Immunosensor for the Determination of Immunoglobulin G
... IgM and albumin were tested as potential interferents which can be presented in tested samples. Concentration of the interferents was derived from their standard plasmatic levels which is 0.4 – 2.3 mg/ml for IgM and 35 – ...
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Varicella-Specific Immunoglobulin G Titers in Commercial Intravenous Immunoglobulin Preparations
... RESULTS: Ten historic lots and 24 current lots were tested. The overall mean value of varicella-specific IgG in the historic lots was 3.07 (SD: 0.70); the current lots had a mean of 3.83 (SD: 0.58). The postvaccine IVIg ...
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