Immunosuppressive effect
Immunosuppressive Effect of Polycyclic Aromatic Hydrocarbons by Induction of Apoptosis of pre-B Lymphocytes of Bone Marrow
... The role of nuclear factor kappa B, as an important fac- tor for survival of the cell, has already been discussed in association with its antagonistic effect on apoptosis. It has been proved that the nuclear ...
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Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway
... important effect on antitumor response in Burkitt’s lymphoma ...the immunosuppressive effect of pumc-91 or pumc-91/ADM on DCs might have different ...
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Immunosuppressive effect of hispidulin in allergic contact dermatitis
... and immunosuppressive properties of hispidulin have been appreciated, the effect of hispidulin on ACD via Th1 cell activities has not been explored ...the immunosuppressive effect of purified ...
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NLGP counterbalances the immunosuppressive effect of tumor-associated mesenchymal stem cells to restore effector T cell functions
... In addition to mature stromal elements affecting carcino- genesis, attention has now shifted to the progenitor cells of the stroma, the mesenchymal stem cells (MSCs). MSCs are recruited to the site of tissue injury for ...
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An in vitro model to assess the immunosuppressive effect of tick saliva on the mobilization of inflammatory monocyte-derived cells
... Figure 1 Dual effect of tick saliva in vivo on the recruitment of leukocyte infiltrates to skin and dendritic cells to draining lymph nodes. A surgical monofilament suture was positioned on the back of a C57BL/6 ...
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Immunosuppressive effect of mesenchymal stem cell-derived exosomes on a concanavalin A-induced liver injury model
... suppressive effect on con-A- induced liver injury model while it was not observed in the injured liver, and it is possible to surmise some se- creting factors from MSC played an important role in the expression of ...
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Gene expression profiling of macrophages: implications for an immunosuppressive effect of dissolucytotic gold ions
... Since we were most interested in the effect of gold on inflammation we analysed a cluster of genes involved in inflammation and found 34 genes differentially regu- lated. In this group we found decreased ...
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IMMUNOSUPPRESSIVE EFFECT OF SWERTIA CHIRATA BUCH HAM ON SWISS ALBINO MICE
... ABSTRACT: Swertia chirata Buch Ham (Gentianaceae) commonly known as chirata is a perennial herb. The present study was undertaken to evaluate the immunomodulatory effect of methanolic extract of S. chirata aerial ...
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Combining surgery and immunotherapy: turning an immunosuppressive effect into a therapeutic opportunity
... the effect of neoadjuvant anti-PD-1 inhibitor nivolu- mab in resectable non-small cell lung cancer patients, major pathological responses were observed in both PD-L1 positive and negative tumors that were ...
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Immunosuppressive effects of pharmaceuticals
... of immunosuppressive effect even in short-term courses of such antibiotics as penicillin, streptomycin, tetracyclines, antituberculous and antifungal drugs (Khaitov and Ataullakhanov, 2012; Pokrovsky et ...
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Combination treatment with oncolytic Vaccinia virus and cyclophosphamide results in synergistic antitumor effects in human lung adenocarcinoma bearing mice
... Moreover, after combination treatment we did not see enhanced viral titers in the organs of mice suggesting that CPA has no immunosuppressive effect in our experi- mental model. Immune-related effects of ...
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Interleukin (IL)-10 Induced by CD11b+ Cells and IL-10-Activated Regulatory T Cells Play a Role in Immune Modulation of Mesenchymal Stem Cells in Rat Islet Allografts
... beneficial effect on graft sur- ...an immunosuppressive effect in our rat islet transplantation model, and that treatment with autologous MSC-plus-CsA significantly enhances rat islet allograft ...
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Gilz-Activin A as a Novel Signaling Axis Orchestrating Mesenchymal Stem Cell and Th17 Cell Interplay
... an immunosuppressive phenotype induces Gilz translocation from the cytosol to the nucleus, where it binds to Activin A and inos ...the immunosuppressive effect of Gilz in ...the ...
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The Preventative Effect of Dietary Apostichopus japonicus on Intestinal Microflora Dysregulation in Immunosuppressive Mice Induced by Cyclophosphamide
... the effect of dried ...regulatory effect of dietary ...better effect on intestinal mucosa protection, but we still didn’t know which component in ...
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Interleukin-4 inhibits secretion of interleukin-1beta in the response of human cells to mycobacterial heat shock proteins.
... Since chronic inflammatory disease has been demonstrated to involve persistent and active proinflammatory cytokine se- cretion, it was important to elucidate whether the effect of IL-4 on mycobacterium-treated ...
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Methotrexate effect on immunogenicity and long term maintenance of adalimumab in axial spondyloarthritis: a multicentric randomised trial
... The two treatment groups did not differ in clinical response or CRP level at the end of the prospective study. However, ADA- positive patients showed low adalimumab concentration and poor response, particularly those ...
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Effects of an immunosuppressive treatment on the rat prostate
... of immunosuppressive drugs on the morphology, ultrastructure, and expression of proliferating cell nuclear antigen and cytoskeleton proteins in the rat dorsolateral ...for immunosuppressive therapy used in ...
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Characterization of B cell responses in relation to organ transplantation
... (21). Immunosuppressive effects of bortezomib are caused by induction of plasma cell apoptosis ...general effect on cells with high pro- tein ...the effect of bortezomib on activated B cells, as ...
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Noninfectious uveitis: strategies to optimize treatment compliance and adherence
... Abstract: Noninfectious uveitis includes a heterogenous group of sight-threatening ocular and systemic disorders. Significant progress has been made in the treatment of noninfectious uveitis in recent years, particularly ...
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Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice
... Myeloid-derived suppressor cells (MDSC) have been described in inflammatory bowel disease (IBD), but their role in the disease remains controversial. We sought to define the effect of granulocytic MDSC-derived ...
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