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Impaired renal function

Population pharmacokinetics of pomalidomide in patients with relapsed or refractory multiple myeloma with various degrees of impaired renal function

Population pharmacokinetics of pomalidomide in patients with relapsed or refractory multiple myeloma with various degrees of impaired renal function

... comorbid renal conditions. To assess the impact of renal impairment on pomalidomide exposure, a population pharmacokinetics (PPK) model of pomalidomide in rrMM patients with various degrees of ...

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Impaired renal function in a rural Ugandan population cohort

Impaired renal function in a rural Ugandan population cohort

... of impaired renal function, highlighting the need to focus efforts on preventive strategies to delay onset and slow progression of renal ...measure renal function in sub-Saharan ...

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Relationships of Urinary Beta2- microglobulin in Neonates with Impaired Renal Function in Different Stages of Hypoxic Ischaemic Encephalopathy

Relationships of Urinary Beta2- microglobulin in Neonates with Impaired Renal Function in Different Stages of Hypoxic Ischaemic Encephalopathy

... In this study, 42 term newborn babies before 24 hours of age, those who failed to take spontaneous breathing within 5 minutes of the complete delivery were taken as cases and 40 healthy term newborns were taken as ...

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Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease

Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease

... and renal impair- ment has been identified as a chronic low grade inflam- matory state ...and renal impairment relative to pa- tients with CAD ...of impaired renal function on vascular ...

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Digital microvascular reactivity does not decline with impaired renal function in chronic kidney disease

Digital microvascular reactivity does not decline with impaired renal function in chronic kidney disease

... by impaired renal ...declined renal function in our study, which is possibly due to the increased BP in more advanced CKD patients, as our subsequent analysis revealed that RHI was ...

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Over 27% Of Type II Diabetic Patients Studied At Parirenyatwa Diabetic Clinic In Zimbabwe Have Evidence Of Impaired Renal Function

Over 27% Of Type II Diabetic Patients Studied At Parirenyatwa Diabetic Clinic In Zimbabwe Have Evidence Of Impaired Renal Function

... Duration of intake of medication (most were on Metformin®and Glibenclamide®) ranged from 1 year to 35 years. It is apparent (Figure 3) that those who had been on treatment for more than 20 years were more likely to have ...

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Impaired renal function and increased urinary isoprostane excretion in Ghanaian women with pre-eclampsia

Impaired renal function and increased urinary isoprostane excretion in Ghanaian women with pre-eclampsia

... was significantly decreased in the women with pre-eclampsia, implying impaired renal function in this group. Moreover, the negative correlation between eGFR and isoprostane excretion in the women ...

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Impaired renal function and associated risk factors in newly diagnosed HIV-infected adults in Gulu Hospital, Northern Uganda

Impaired renal function and associated risk factors in newly diagnosed HIV-infected adults in Gulu Hospital, Northern Uganda

... the impaired renal function and charac- teristics of studied ...of renal failure would have been higher than this if we had more of our participants in advanced stages of HIV-infection since ...

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Heart failure in patients of acute ST elevation myocardial infarction with impaired renal function

Heart failure in patients of acute ST elevation myocardial infarction with impaired renal function

...  This study was conducted at National Institute of Cardiovascular Diseases (NICVD) within a period of one year from January 2011 to December 2011 after the approval of ethical review committee. For this purpose, 100 ...

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Prescription of Drugs in Children with Impaired Renal Function

Prescription of Drugs in Children with Impaired Renal Function

... 4. Drugs with a narrow therapeutic range need to reduce the dosage size instead of the interval. Because prescription of these drugs in impaired renal function may result in toxic or nontherapeutic ...

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Increased body fat rather than body weight has harmful effects on 4-year changes of renal function in the general elderly population with a normal or mildly impaired renal function

Increased body fat rather than body weight has harmful effects on 4-year changes of renal function in the general elderly population with a normal or mildly impaired renal function

... kidney function greater than that attributed to normal aging could be a marker of progressive renal disease, measurements of body fat may help to identify individuals who were susceptible to significant ...

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Epidural anaesthesia for open prostatectomy in a patient with  impaired renal function

Epidural anaesthesia for open prostatectomy in a patient with impaired renal function

... Benign prostatic hyperplasia represents an over-growth of prostatic glandular tissue and smooth muscle. The cause is unknown but hormonal factors may play an important role since BPH does not occur in Eunuchs or ...

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Robotic stereotactic ablative radiotherapy for renal cell carcinoma in patients with impaired renal function

Robotic stereotactic ablative radiotherapy for renal cell carcinoma in patients with impaired renal function

... As a possible therapeutic approach robotic stereotactic ablative radiotherapy (SABR) is currently under investi- gation as a non-invasive treatment option for patients with RCC. Renal cell carcinoma is frequently ...

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Persistent Sterile Leukocyturia Is Associated With Impaired Renal Function in Human Immunodeficiency Virus Type 1-Infected Children Treated With Indinavir

Persistent Sterile Leukocyturia Is Associated With Impaired Renal Function in Human Immunodeficiency Virus Type 1-Infected Children Treated With Indinavir

... frequently had an increase in serum creatinine levels of >50% above normal. Younger children have an addi- tional risk for renal complications. The impairment of the renal function in these ...

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Clinical relevance of procalcitonin and C reactive protein as infection markers in renal impairment: a cross sectional study

Clinical relevance of procalcitonin and C reactive protein as infection markers in renal impairment: a cross sectional study

... alongside renal function, and no significant associ- ation was found between cardiovascular disease and eGFR ( P = ...of renal function, includ- ing dialysis ...with impaired ...

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Adverse Drug Events and Renal Function

Adverse Drug Events and Renal Function

... potassium wasting induced thaizide diuretics, 17 and the potassium retention caused by trimethoprim-sulfamethoxazole (TMP-SMX). 18 Second, in patients with impaired renal function, the therapeutic ...

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Laboratory prediction of the requirement for renal replacement in acute falciparum malaria

Laboratory prediction of the requirement for renal replacement in acute falciparum malaria

... with impaired renal function on admission (creatinine clearance < 60 ml/min) (n = 84) had their laboratory indices of ATN/AKI ...the renal failure index (RFI), the urinary osmolality, the ...

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The prevalence of renal impairment in individuals seeking HIV testing in Urban Malawi

The prevalence of renal impairment in individuals seeking HIV testing in Urban Malawi

... of impaired renal function seems to be higher in HIV-positive individ- uals even though the most advanced stages of reduced eGFR occurred in two HIV-negative individuals in our ...of renal ...

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Racial differences in the association of NT-proBNP with risk of incident heart failure in REGARDS

Racial differences in the association of NT-proBNP with risk of incident heart failure in REGARDS

... an entry/eligibility criterion in multiple recently conducted clinical trials (32–34). Because Black race is associated with relatively low NP levels, this may be a reason behind the marked underrepresenta- tion of Black ...

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Kidney disease as a determinant of cognitive decline and dementia

Kidney disease as a determinant of cognitive decline and dementia

... moderate-to-severe impaired renal function was associated with incident cognitive impairment after 2 years in a large cohort of older subjects ...kidney function estimated by two different ...

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