In situ gelling
In Situ Gelling System - An Overview
... This polymer was discovered in the 50's in the course of a screening to identify micro organisms that produced water soluble gums of commercial interest. The first industrial production was carried out in 1960 and the ...
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FORMULATION AND IN VITRO EVALUATION OF IN SITU GELLING LIQUID SUPPOSITORY OF PROMETHAZINE HCL
... in situ gelling thermoreversible liquid suppository of PMZ HCl was developed using poloxamer P407, poloxamer P188 and mucoadhesive polymer ...in situ gelling and mucoadhesive liquid ...
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Floating in situ gelling gellan formulations of metformin hydrochloride
... in-situ gelling formulation may represent a promising approach of novel liquid oral drug delivery system which may improve the patient compliance especially for elderly and patients with swallowing ...
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Optimization of in situ gelling system for nasal administration of celecoxib
... in-situ gelling system for nasal route could enhance the bioavailability and therapeutic activity of the ...in-situ gelling system of Celecoxib using polymers like pluronic F127, carbopol 934P ...
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FORMULATION AND ASSESSMENT OF GEMIFLOXACIN MESYLATE OCULAR IN SITU GELLING SYSTEM
... In situ gels are one of the most successful means of delivering the drug at ocular site with maximum bioavailability, which undergoes gelation upon instillation as drops into the eye due to physicochemical changes ...
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Ion-activated In Situ Gelling Ophthalmic Delivery Systems of Azithromycin
... in situ gelling ophthalmic solution leading to increased precorneal contact time and prolonged drug ...were gelling capacity and rheological ...in situ gels can be successfully used to prolong ...
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Sustained ophthalmic delivery of gatifloxacin from In situ gelling system
... were carried out using Brookfiled DV-111+ Rheometer Thus, with the use of these in situ gelling systems, with spindle LV-3. The prepared solution was allowed to residence time of the drug in the eye is ...
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Formulation and Evaluation Of PH Triggered In Situ Gelling System of Levofloxacin
... The drug release from the prepared formulation is studied by using a modified method reported earlier. The test solution was placed in a circular plastic cup of 2.5cm internal diameter and1.2cm depth. This was in turn ...
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Studies on in situ gelling system for better ocular drug therapy.
... in situ gel forming system is substantiated by the property of its aqueous solution to transform into stiff gels when the temperature is ...the gelling capacity and rheological properties of the delivery ...
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FORMULATION AND EVALUATION OF IN SITU GELLING OCULAR SYSTEM OF OFLOXACIN
... in-situ gelling polymers. The in-situ gelling polymers undergo sol‐to‐gel phase transition on exposure to the physiological conditions present in the ...
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FORMULATION AND EVALUATION OF FLOATING ORAL IN SITU GELLING SYSTEM OF LOSARTAN POTASSIUM
... Rheological Studies: The two main pre-requisites of in-situ gelling systems are optimum viscosity (to ingest orally as a liquid dosage form) and gelling capacity (speed and extent of gelation). ...
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PH-INDUCED IN SITU GELLING SYSTEM OF LOMEFLOXACIN FOR SUSTAINED OCULAR DELIVERY
... Prepared in-situ gelling systems were subjected for ocular irritancy studies. A total four albino rabbits (male) weighing 1.5-2 kg was used for the present study. The sterile formulations were instilled ...
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Biodegradable in situ gelling delivery systems containing pilocarpine as new antiglaucoma formulations: effect of a mercaptoacetic acid/N-isopropylacrylamide molar ratio
... in situ gelling system prepared from carboxyl-terminated PNIPAAm of high molecular weight may have a lower thermal phase transition tempera- ture and slower degradation rate than those from the low ...
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In SITU Gelling System as a Vaccine Carrier Chandra HS 1, Basant Malik3 , Goutam Rath 2, Amit K. Goyal2
... Apart from this aluminum hydroxide has various drawbacks also, like it is only used in parenteral vaccine formulation not in mucosal vaccines. It is pretty weak adjuvant and rarely provokes cellular immune ...
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Study of effect of sodium alginate and calcium carbonate composition difference on in situ gelling gastroretentive amoxicillin liquid formulation
... In Situ Gelling Gastro retentive Amoxicillin Liquid ...Formulation. Gelling capacity was evaluated based on a graded response which indicates rapidity of gelation and time taken by the gel to ...
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DESIGN AND DEVELOPMENT OF pH-TRIGGERED IN SITU GELLING SYSTEM OF CIPROFLOXACIN
... in situ gelling system of ...in situ gel-forming systems that are instilled as drops into the eye and undergo a sol–gel transition in the ...in situ Gelling system of ciprofloxacin to ...
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PATIENT COMPLIANT OCULAR IN SITU GELLING SYSTEM OF AZITHROMYCIN DIHYDRATE
... in situ gelling ophthalmic solution leading to increased precorneal adherence time and prolonged drug delivery, and hence increase ...were gelling capacity and rheological behaviour and antimicrobial ...
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FORMULATION AND EVALUATION OF NOVEL FLOATING IN SITU GELLING SYSTEM OF MACROLIDE ANTIBIOTIC USING DIFFERENT GELLING POLYMERS
... In situ gelling system is a novel approach in the FDDS. In situ gels which when administered are in solution form, but as it comes in contact with gastric fluids, it forms ...in situ gels may ...
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In Situ Gelling System: A Review
... in situ gels offer the primary requirement of a successful controlled release product that is increasing patient ...in situ gels for controlled release of various drugs provides a number of advantages over ...
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Formulation and Evaluation of PH Triggered In Situ Gelling System of Levofloxacin
... FORMULATION OF RAMIPRIL LOADED SOLID LIPID NANOPARTICLES Ramipril loaded solid lipid nanoparticles is prepared by using two different type of lipids monoglycerides glyceryl monostearate [r] ...
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