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in-vitro release studies

Design and evaluation of matrix type and membrane controlled transdermal delivery systems of nicotine suitable for use in smoking cessation

Design and evaluation of matrix type and membrane controlled transdermal delivery systems of nicotine suitable for use in smoking cessation

... In vitro release studies of transdermal patches showed a biphasic release pattern, with diffusion as the dominating mechanism of drug release for the matrix type, while the ...

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TRANSDERMAL PATCH OF RAMIPRIL LOADED CHITOSAN NANOPARTICLES DISPERSED IN CARBOPOL GEL

TRANSDERMAL PATCH OF RAMIPRIL LOADED CHITOSAN NANOPARTICLES DISPERSED IN CARBOPOL GEL

... In vitro Franz’s diffusion studies of Transdermal patches of Ramipril though chitosan nanoparticles dispersed in carbopol gels: In vitro release studies can be performed in a modified ...

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DESIGN AND CHARACTERIZATION OF BUCCAL PATCHES OF CANDESARTAN CILEXETIL

DESIGN AND CHARACTERIZATION OF BUCCAL PATCHES OF CANDESARTAN CILEXETIL

... In-vitro release studies were carried out by conducting dissolution profile assessment of the prepared formulations of the drug substance and they were predominantly done by using the USP Type-II ...

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Design and Pharmacodynamic Evaluation of Optimized Microporous Osmotic Tablets of Venlafaxine Hydrochloride

Design and Pharmacodynamic Evaluation of Optimized Microporous Osmotic Tablets of Venlafaxine Hydrochloride

... sustained release profile for 24 h. Optimization studies were performed to study the effect of concentration of osmotic agent and pore former on drug release (t 50% and t 90% ...in vitro ...

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Application of solvent injection method to develop stable, sustained release solid lipid Nanoparticles of Curcumin

Application of solvent injection method to develop stable, sustained release solid lipid Nanoparticles of Curcumin

... drug release pattern in the in vitro release studies ...burst release at the initial state followed by a sustained release state) with a total release percent of ...the ...

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Formulation and evaluation of gastroretentive tablets of Furosemide (Evaluation based on drug release kinetics and factorial designs)

Formulation and evaluation of gastroretentive tablets of Furosemide (Evaluation based on drug release kinetics and factorial designs)

... The swelling index of the tablets increases with an increase in the polymer content as can be seen from the data given in tables-9 & 10. In vitro floating studies were performed by placing tablets in ...

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Sustained Release Dental Implants

Sustained Release Dental Implants

... In vitro drug release studies: In vitro drug release was performed by taking five implants with the drug (separate formulation) in three separate beaker containing 5 ml of isotonic ...

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“Development and Evaluation of Novel Site Specific Periodontal Film of Minocycline Hydrochloride for Periodontal Diseases” by Indira Raheja, Sushma Drabu, Kanchan Kohli, India.

“Development and Evaluation of Novel Site Specific Periodontal Film of Minocycline Hydrochloride for Periodontal Diseases” by Indira Raheja, Sushma Drabu, Kanchan Kohli, India.

... in vitro antibacterial activity. In vitro release from periodontal films was fit to different equations and kinetic models like zero order, first‐order equations and Hixson‐Crowell, Higuchi models ...

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Formulation and in vitro Evaluation of Glipizide Nanosponges

Formulation and in vitro Evaluation of Glipizide Nanosponges

... in vitro drug release studies for the prepared formulation were conducted for a period of 12 hrs using an LAB INDIA DS8000 model dissolution tester USP Type-1 apparatus (rotating basket) set at 50 ...

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DEVELOPMENT AND IN-VITRO EVALUATION OF CARVEDILOL LOADED MUCOADHESIVE BUCCAL TABLET

DEVELOPMENT AND IN-VITRO EVALUATION OF CARVEDILOL LOADED MUCOADHESIVE BUCCAL TABLET

... In- vitro drug release studies demonstrated that Carvedilol release from the selected tablets followed diffusion kinetics with a maximum drug release and it is confirmed that the tablet ...

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Design and Characterization of Pregabalin Swellable Core Osmotic Pumps

Design and Characterization of Pregabalin Swellable Core Osmotic Pumps

... in vitro and in vivo performance of Pregabalin, formulated and evaluated in two different SCT core configurations: homogeneous- core (single layer) and bi-layer core ...In vitro dissolution studies ...

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NIZATIDINE BASED FLOATING MICROSPHERES BY IONOTROPIC GELATION TECHNIQUE - MORPHOLOGY AND RELEASE CHARACTERISTICS

NIZATIDINE BASED FLOATING MICROSPHERES BY IONOTROPIC GELATION TECHNIQUE - MORPHOLOGY AND RELEASE CHARACTERISTICS

... Stability studies of optimized Nizatidine microspheres as per ICH guidelines was carried out for 6months at 40°C ± 2°C/75% RH ± 5% RH showed in the Table ...in vitro drug release ...in vitro ...

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FORMULATION AND EVALUATION OF SUSTAINED RELEASE MICROSPHERES OF ATORVASTATIN USING CHITOSAN AND ALGINATE

FORMULATION AND EVALUATION OF SUSTAINED RELEASE MICROSPHERES OF ATORVASTATIN USING CHITOSAN AND ALGINATE

... in vitro drug release studies were performed using Dissolution Apparatus USP Type II (Rotating Paddle DISSO2000, Lab ...The release rate from these microspheres were conducted in a medium of ...

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EFFECT OF LUMINAL pH CHANGES ON GUAR GUM HPMC E15 LV MIXED MATRIX TABLETS FOR MESALAMINE DRUG DELIVERY TO COLON AND STUDY ON IN  VITRO CHARACTERISTICS IN TWO DIFFERENT DISSOLUTION MODELS vs  MARKETED FORMULATION

EFFECT OF LUMINAL pH CHANGES ON GUAR GUM HPMC E15 LV MIXED MATRIX TABLETS FOR MESALAMINE DRUG DELIVERY TO COLON AND STUDY ON IN VITRO CHARACTERISTICS IN TWO DIFFERENT DISSOLUTION MODELS vs MARKETED FORMULATION

... tablets release pattern cannot be affected by pH changes in the colon, and integrity of the GMM5 was better than marketed enteric coated delayed release ...drug release profile. But the further ...

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DESIGN, CHARACTERIZATION AND PHARMACOKINETIC STUDIES OF SOLID LIPID NANOPARTICLES OF ANTIHYPERTENSIVE DRUG TELMISARTAN

DESIGN, CHARACTERIZATION AND PHARMACOKINETIC STUDIES OF SOLID LIPID NANOPARTICLES OF ANTIHYPERTENSIVE DRUG TELMISARTAN

... pharmacokinetic studies were performed in Albino Wistar rats to determine the drug delivery potential of ...in vitro release from SLN demonstrated a sustained release with ...stability ...

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FORMULATION AND EVALUATION OF BILAYER TABLETS OF SUSTAINED RELEASE NSAID’s AND IMMEDIATE RELEASE PROTON PUMP INHIBITOR

FORMULATION AND EVALUATION OF BILAYER TABLETS OF SUSTAINED RELEASE NSAID’s AND IMMEDIATE RELEASE PROTON PUMP INHIBITOR

... in vitro drug release studies of Esomeprazole and Diclofenac sodium tablets were carried out using USP dissolution apparatus type- II (paddle type) at 50 rpm ...drug release was measured by UV ...

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FORMULATION AND EVALUATION OF NYSTATIN LOADED NIOSOMES

FORMULATION AND EVALUATION OF NYSTATIN LOADED NIOSOMES

... In vitro diffusion studies of all formulations were carried out in fabricated diffusion ...drug release from niosomes decreases with increase in the concentration of surfactant and also from the data ...

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A Comparative Study between Market products and Immediate Release Loratadine Tablets Formulation using different Superdisintegrants

A Comparative Study between Market products and Immediate Release Loratadine Tablets Formulation using different Superdisintegrants

... drug release Immediate release of loratadine tablets were subjected to in vitro drug release studies for 1hr and release profile includes a plot of percent release of drug ...

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Fabrication of Gelatin/Karaya gum blend microspheres for the controlled release of Distigmine bromide

Fabrication of Gelatin/Karaya gum blend microspheres for the controlled release of Distigmine bromide

... SEM studies reveal that the beads were spherical in shape with smooth ...in vitro release study indicates the distigmine bromide released in a controlled ...in vitro release kinetics ...

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LESS TOXIC NANOPARTICLES OF PLATINUM BASED ANTI CANCER DRUG

LESS TOXIC NANOPARTICLES OF PLATINUM BASED ANTI CANCER DRUG

... In Group 1: 5 animals died in 48 h, 3 animals died between 24-40 h after administration of cisplatin injection. The animals in group 1 were inactive showed signs like incomplete closing of the lid, strobes reaction, ...

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