In-Vivo
BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies
... in vivo results suggest that loss of one BMPR-1A or ActR-1A allele does not compromise renal development, whereas loss of one BMP2 allele may have a minor effect on renal ...
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The role of p53 in vivo during skeletal muscle post natal development and regeneration: studies in p53 knockout mice
... tumour suppressor gene p53 is a transcription factor commonly considered to be the “gatekeeper for cell replication”, being impor- tant for maintaining the quiescent state of cells (Levine et al., 1991). The development ...
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Localized sequence heterogeneity in the long terminal repeats of in vivo isolates of equine infectious anemia virus.
... PCR amplification of EIAV sequences from horses. The EIAV sequence heterogeneity present in vivo was explored by analyzing the viral sequences from three clinically ill and four healthy, seropositive, carrier ...
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A secreted luciferase for ex-vivo monitoring of in vivo processes
... range covering over 5 orders of magnitude, and correlated well with values obtained using the CCD camera (Fig. 1b). Further, Gluc activity could also be detected in the urine, albeit to a lesser extent than in the blood, ...
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TTF 1/NKX2 1 up regulates the in vivo transcription of nestin
... ABSTRACT TTF-1/NKX2.1, also known as T/EBP, is a homeodomain-containing gene involved in the organogenesis of the thyroid gland, lung and ventral forebrain. We have already reported that in 3T3 cells, TTF-1/NKX2.1 ...
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Differential regulation of cumulus cell transcription during oocyte maturation in vivo and in vitro
... duplicates. Actin beta (ACTB) mRNA was chosen as a housekeeping gene. mRNA quantifications were obtained by the comparative Ct method, using DDCt. Results were expressed as fold change with respect to the IVF-MII group, ...
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Tryptase and chymase are angiogenic in vivo in the chorioallantoic membrane assay
... ABSTRACT Human mast cells (MCs) are divided in two types depending on the expression of tryptase and chymase in their granules. Literature data indicate that both tryptase and chymase are angiogenic, but there is ...
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Two paternal genomes are compatible with dopaminergic in vitro and in vivo differentiation
... in vivo differentiation potential of uniparental parthenogenetic (PG) and gynogenetic (GG) embryonic stem (ES) cells of several species have been studied, the capacity of androgenetic (AG) ES cells to develop into ...
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Gene disruption/knock in analysis of mONT3: vector construction by employing both in vivo and in vitro recombinations
... In this study, we have performed the expression pattern and gene disruption analyses of mONT3. The ONT family is a rela- tively new group of secreted signals that seem to play regulatory roles in vertebrate embryogenesis ...
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In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis
... In spite of its central role in Toxoplasma growth and survival, the PV has been challenging to study due to excessive parasite and/or host contamination using traditional biochemical frac- tionation approaches (31, 32). ...
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Humoral and cellular immune responses induced by the urease derived peptide Jaburetox in the model organism Rhodnius prolixus
... in vivo activa- tion of the immune system induced by Jaburetox rendered the insects more susceptible to bacteria proliferation be- cause it consumes defense resources that cannot be later employed to withstand the ...
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The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch mediated signaling
... in vivo relevance of Adam10 in the epidermis, we have selectively disrupted Adam10 during skin morphogenesis and in adult ...in vivo, and thus as a central regulator of skin development and ...
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MR−Based Molecular Imaging of the Brain: The Next Frontier
... A natomic images have always been the center of gravity in the daily work of radiologists. They provide the basis of many diagnoses supplemented by physiologic MR imaging data or metabolic profiling if necessary. Despite ...
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Creating frog heart as an organ: in vitro induced heart functions as a circulatory organ in vivo
... Fig. 1. In vitro cardiomyocyte induction and in vivo ectopic heart formation. (A) Experimental protocol of the in vitro cardiomyocyte induction and ectopic heart transplantation. For further details, see Materials ...
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Phytochemical Investigation of Eleusine Indica for In Vivo Anti Hypertensive Activity
... grass belonging to family poaceae. The plant is used for deforming, eliminate or reduce cough and lung troubles, dysentery, heart problems and high blood pressure, spleen and liver complaints, bladder and kidney stone ...
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In vivo forced expression of myocardin in ventricular myocardium transiently impairs systolic performance in early neonatal pig heart
... Fig. 2. Analysis of myocd-A and myocd-B expression in vivo and in vitro. (A) Positions of the oligonucle- otides 273 and 270 (horizontal arrows) over porcine myocd-A and myocd-B exon 10 and exon 12 (white boxes) ...
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Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane bound NADH oxidase A new action for an old drug
... Animal model, in vivo nitrate tolerance. New Zealand White rabbits of either sex, weighing 3–6 kg, were studied. Four groups were stud- ied: an untreated group (no nitroglycerin or hydralazine), a hydrala- ...
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In vivo models in cancer research
... Since their introduction almost a century ago, chick embryo model systems involving the technique of chorioallantoic grafting have proved invaluable in the in vivo studies of tumor development and angiogenesis and ...
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In vivo imaging of Drosophila wing heart development during pupal stages
... mesenchymal cells. Cell divisions can be observed almost until the end of wing heart maturation (see supplemental movie M05). It has previously been shown that duf-lacZ is expressed in founder cells of adult somatic ...
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The various aspects of genetic and epigenetic toxicology: testing methods and clinical applications
... With the development of cancer researches, anticancer drugs have been widely used for the treatment of various types of human malignancies [47, 48]. In general, a large number of patients with advanced cancer receive ...
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