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Inclusion Body

Inclusion body myositis: therapeutic approaches

Inclusion body myositis: therapeutic approaches

... Abstract: The idiopathic inflammatory myopathies are a heterogeneous group of diseases that include dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and other less common myopathies. ...

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Original Article Pathological findings in sporadic inclusion body myositis and GNE myopathy

Original Article Pathological findings in sporadic inclusion body myositis and GNE myopathy

... [9] Tanboon J, Rongsa K, Pithukpakorn M, Boonyapisit K, Limwongse C and Sangruchi T. A novel mutation of the GNE gene in distal my- opathy with rimmed vacuoles: a case with in- flammation. Case Rep Neurol 2014; 6: 55-59. ...

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Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins

Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins

... by inclusion body isolation [for recent reviews on various aspects of inclusion body formation and renaturation of inclusion body proteins please refer also to ...[11-18]]. ...

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Molecular differentiation and pathogenicity of Aviadenoviruses isolated during an outbreak of inclusion body hepatitis in South Africa

Molecular differentiation and pathogenicity of Aviadenoviruses isolated during an outbreak of inclusion body hepatitis in South Africa

... Fowl adenoviruses (FAdVs) are common infectious agents of birds involved in a number of economically important diseases in poultry (McFerran & Smyth 2000) and are implicated in inclusion body hepatitis ...

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Custom made inclusion bodies: impact of classical process parameters and physiological parameters on inclusion body quality attributes

Custom made inclusion bodies: impact of classical process parameters and physiological parameters on inclusion body quality attributes

... that IBs can be produced in high concentration (so that the amount of generated product often outweighs the additional downstream steps), IB based processes are believed to fundamentally boost time/space yields for ...

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A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis

A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis

... Diagnostic utility of categorising the pattern of p62 staining The pattern of p62 staining could be categorised into four distinct groups ( fi gure 1G – J). Aggregates observed in IBM were present in vacuolated and ...

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Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration

Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration

... Choreoathetoid involuntary movements are rarely reported in patients with frontotemporal lobar degeneration (FTLD), suggesting their exclusion as a supportive feature in clinical diagnostic criteria for FTLD. Here, we ...

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The updated retrospective questionnaire study of sporadic inclusion body myositis in Japan

The updated retrospective questionnaire study of sporadic inclusion body myositis in Japan

... Sporadic inclusion body myositis (sIBM) is the most fre- quent inflammatory muscle disease in middle-aged and elderly people [3, 10]. sIBM symptoms typically include muscle weakness/atrophy in the ...

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Inclusion body myositis. Clinical aspects

Inclusion body myositis. Clinical aspects

... sporadic inclusion body myositi s or motor neuron disease was considered as only motor dysfuncti on was ...sporadic inclusion body myositi ...

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Application of an E. coli signal sequence as a versatile inclusion body tag

Application of an E. coli signal sequence as a versatile inclusion body tag

... Fusion to ssTorA has been successfully used to trans- port heterologous proteins such as GFP across the E. coli inner membrane into the periplasm [51]. Instead, in the present work we demonstrate efficient IB-formation ...

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Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis

Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis

... Sporadic inclusion body myositis (IBM) is the most common primary myopathy in the elderly, but its pathoetiology is still unclear. Perturbed myocellular calcium (Ca 2+ ) homeostasis can exacerbate many of ...

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Intravenous immune globulin in hereditary inclusion body myopathy: a pilot study

Intravenous immune globulin in hereditary inclusion body myopathy: a pilot study

... Patient 3 is a 39-year-old woman of Bohemian/Czech/ French Canadian ancestry diagnosed with HIBM at the age of 31 years. Following a year of progressive tripping and falling, she awoke one day with numbness from the ...

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A New Complication of Stem Cell Transplantation: Measles Inclusion Body Encephalitis

A New Complication of Stem Cell Transplantation: Measles Inclusion Body Encephalitis

... Measles inclusion body encephalitis (MIBE) is a disease of the immunocompromised host and typically occurs within 1 year of acute measles infection or ...

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Misdiagnosis of inclusion body myositis: two case reports and a retrospective chart review

Misdiagnosis of inclusion body myositis: two case reports and a retrospective chart review

... Sporadic inclusion body myositis (s-IBM) is one of sev- eral chronic adult inflammatory myopathies. Its preva- lence varies, but it may be as high as 35 per 1 million adults over age 50 years, with a slight ...

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Multicenter questionnaire survey for sporadic inclusion body myositis in Japan

Multicenter questionnaire survey for sporadic inclusion body myositis in Japan

... Sporadic inclusion body myositis (sIBM) is the most com- mon form of inflammatory myopathy in those over the age of 50 years in Western countries [1 – ...

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Proteomic study of sporadic inclusion body myositis

Proteomic study of sporadic inclusion body myositis

... Sporadic inclusion body myositis (s-IBM) is a sporadic inflammatory muscle disease that occurs most frequently in middle-aged and elderly individuals ...

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Dysphagia in Patients with Sporadic Inclusion Body Myositis: Management Challenges

<p>Dysphagia in Patients with Sporadic Inclusion Body Myositis: Management Challenges</p>

... Botulinum toxin and rehabilitation treatment in inclusion body myo- sitis for severe oropharyngeal dysphagia.. Inclusion body myositis associated with pro- gressive dysphagia: treatment [r] ...

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Affinity Based Nano-Magnetic Particles for Purification of Recombinant Proteins in Form of Inclusion Body

Affinity Based Nano-Magnetic Particles for Purification of Recombinant Proteins in Form of Inclusion Body

... Background: Protein purification is the most complicated issue in the downstream processes of recombinant protein production; therefore, improved selective purification methods are important. Affinity-based protein ...

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Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease

Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease

... Boid inclusion body disease (BIBD) is a progressive, usually fatal disease of constrictor snakes, characterized by cytoplasmic in- clusion bodies (IB) in a wide range of cell ...boid inclusion ...

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Molecular Identification of Fowl Adenovirus Associated with Inclusion Body Hepatitis in Iran

Molecular Identification of Fowl Adenovirus Associated with Inclusion Body Hepatitis in Iran

... Inclusion body hepatitis (IBH) has been occurring as an economically important and reemerging disease of broiler breeder and broiler chickens in several countries (9, 24, 29- ...

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