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induced pluripotent stem (iPS) cell

Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development

Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development

... in stem cell biology and microfl uidic fabri- cation technology have established the foundation to develop organ-inspired high-throughput in vitro ...human induced pluripotent stem ...

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Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis

Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis

... human-induced pluripotent stem cell-derived mesenchymal stem cells (hiPS-MSC-Exos) could promote angiogenesis of ischemic tissue in limb ischemia and skin defects [17, ...and ...

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Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury

Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury

... Induced pluripotent stem cells (iPSC) are pluripotent stem cells generated by reprogramming somatic cells ...(induced pluripotent stem cell-derived ...

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Long-term Safety and Efficacy of Human-Induced Pluripotent Stem Cell (iPS) Grafts in a Preclinical Model of Retinitis Pigmentosa

Long-term Safety and Efficacy of Human-Induced Pluripotent Stem Cell (iPS) Grafts in a Preclinical Model of Retinitis Pigmentosa

... surgery- induced rescue described in the RCS rat (17–22) were avoided as much as possi- ble by the study of mitomycin-C–treated stem cell grafts as control ...of iPS-derived RPE in the RCS ...

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Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation

Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation

... patient-specific iPS cell clones were fixed for 20 minutes at room temperature in 4% parafor- maldehyde in PBS and then permeabilized with Triton X-100 for 30 ...of iPS cells are listed in ...

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Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation

Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation

... that pluripotent FOP iPS cells can be generated without a BMP inhibitor using either the retrovirus or episomal ...make iPS cells from FOP fibroblasts by the Sendai virus method showed cellular ...

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Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations

Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations

... Figure 3: Effect of the initial hiPSC seeding density on cardiac differentiation. (A) Flow cytometric analysis was carried out at day 18 of differentiation. Left panel histograms show cells in each group stained with ...

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Dynamic instability of genomic methylation patterns in pluripotent stem cells

Dynamic instability of genomic methylation patterns in pluripotent stem cells

... non- stem cells, which maintain methylation patterns in the absence of ...and induced pluripotent stem (iPS) cells tend to lose DNA methylation spontaneously in a process that is ...

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Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes

Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes

... Real-Time Cell Analysis (RTCA) Cardio system, which utilizes impedance tech- nology to quantify CM-beating properties, has been previously reported as an emerging method to quantify cardiac contractility ...

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Temporal epigenetic modifications differentially regulate ES cell like colony formation and maturation

Temporal epigenetic modifications differentially regulate ES cell like colony formation and maturation

... to induced pluripotent stem (iPS) cells by forced expression of the transcription factors Oct4, Sox2, and either Klf4 and cMyc or Nanog and Lin28, using virus-based ...of iPS cells can ...

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Generation of induced pluripotent stem cells from large domestic animals

Generation of induced pluripotent stem cells from large domestic animals

... somatic cell cultures through the lenti- viral transduction of interspecific OSKM (murine and ...The iPS cells derived herein were positive for NANOG by im- munofluorescence, which was used as a ...

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Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

... The iPS cells are the newest class of pluripotent stem cells, which potentially combines the advantages of MSCs and ESCs, ushering in a new era of regenerative medicine ...the cell back to an ...

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Modeling of Sic Power Semiconductor Devices For Switching Converter Applications

Modeling of Sic Power Semiconductor Devices For Switching Converter Applications

... human induced pluripotent stem cells were differentiated into endothelial cells and then injected into immunodeficient mice with ischemic ...applications. iPS cells have also recently begun to ...

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Induced pluripotent stem cells in the study of neurological diseases

Induced pluripotent stem cells in the study of neurological diseases

... ected cell types such as patients’ fi broblasts, providing limited insight into the disease mechanism and yielding ineff ective drug ...using iPS cells to model a disease, Ebert and colleagues generated ...

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Inducible Gata1 suppression expands megakaryocyte erythroid progenitors from embryonic stem cells

Inducible Gata1 suppression expands megakaryocyte erythroid progenitors from embryonic stem cells

... Embryonic stem (ES) and induced pluripotent stem (iPS) cells represent a potential source of megakaryocytes and platelets for transfusion therapies; however, the majority of current ...

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Induced pluripotent stem cells: advances to applications

Induced pluripotent stem cells: advances to applications

... of stem cell technologies, have been based on two for- midable ...between stem cells and the host environment inherent to allogeneic stem cell sources; and second the inability to ...

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Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells

Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells

... of cell suspension (2 × 10 5 cells) containing derived CMs with histamine or with- out histamine was injected into the border zone of the infarcted heart, and each mouse was injected with three ...after ...

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Stem Cell Sources for Regenerative Medicine and Cartilage Tissue Engineering.

Stem Cell Sources for Regenerative Medicine and Cartilage Tissue Engineering.

... both induced pluripotent stem cells and adult tissue progenitors as clinical cell sources for regenerative ...improved cell growth rate, reduced levels of de- differentiation during ...

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Making gametes from pluripotent stem cells – a promising role for very small embryonic-like stem cells

Making gametes from pluripotent stem cells – a promising role for very small embryonic-like stem cells

... including pluripotent stem cells (embryonic ES and induced pluripotent iPS stem cells); gonadal stem cells (spermatogonial SSCs, ovarian OSCs stem cells), bone ...

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The potential and limitations of induced pluripotent stem cells to achieve wound healing

The potential and limitations of induced pluripotent stem cells to achieve wound healing

... embryonic stem cells, iPSC are pluripotent, have the potential for self-renewal, and can differentiate into any adult cell ...other stem cell types in models of regenerative medicine ...

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