Infrapatellar fat pad
Infrapatellar fat pad and knee osteoarthritis
... and infrapatellar fat pad (IPFP), Although the aetiology and progression of this disease are not well understood, it is considered as a multifactorial condition with risk factors including genetics, ...
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The role of environmental factors in regulating the development of cartilaginous grafts engineered using osteoarthritic human infrapatellar fat pad derived stem cells
... with infrapatellar fat pad tissue being obtained from 5 patients with knee osteoarthritis (OA) at joint arthroplasty (1 Male, 4 Females, 50-79 Years ...old). Fat pad was maintained in ...
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Chondrogenesis of infrapatellar fat pad derived adipose stem cells in 3D printed chitosan scaffold
... Infrapatellar fat pad adipose stem cells (IPFP-ASCs) have been shown to harbor chondrogenic potential. When combined with 3D polymeric structures, the stem cells provide a source of stem cells to ...
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Composition function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad
... whole infrapatellar fat pad (FP) (the outer and the inner layers of the FP were not separated, but any fibrous tissue attached to the FP was ...
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Hypoxic conditions increase hypoxia inducible transcription factor 2α and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients
... Stem cells derived from the infrapatellar fat pad (IPFP) are a potential source of stem cells for the repair of articular cartilage defects. Hypoxia has been shown to improve chondrogenesis in adult ...
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Pellet coculture of osteoarthritic chondrocytes and infrapatellar fat pad-derived mesenchymal stem cells with chitosan/hyaluronic acid nanoparticles promotes chondrogenic differentiation
... Donor-matched infrapatellar fat pad and articular cartil- age were obtained from four OA patients (two male and two female, average age 65 ± 3 ...MSCs, infrapatellar fat pad was ...
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Functional Properties of Cartilaginous Tissues Engineered From Infrapatellar Fat Pad Derived Mesenchymal Stem Cells
... cartilage repair, from non-cartilaginous knee joint tissues. It has been demonstrated that tissues from this region including the joint infrapatellar fat pad (IFP) (Dragoo et al., 2003; Wickham et ...
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Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia
... Additional file 3: Figure S1. Effect of body mass index on cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES1) expression in synovial tissues (ST) and the infrapatellar fat ...
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Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes
... Fig2: Annulus-core biochemical analysis of chondrocyte (CC+: with TGF-β3, CC-: without TGF-β3) and infrapatellar fat pad (IFP+: with TGF-β3) seeded constructs subjected to 20% (LHS) or 5% (RHS) ...
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Central defect type partial ACL injury model on goat knees: the effect of infrapatellar fat pad excision
... the infrapatellar fat pad and synovial folds were protected and gently retracted to visualize the ...the infrapatellar fat pad tissue was performed before creating the same ...
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Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study
... The infrapatellar fat pad (IPFP), the local fat around the knee joint, may play an important role in the initiation and progression of knee OA [7, ...
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Meniscus ECM functionalized hydrogels containing infrapatellar fat pad derived stem cells for bioprinting of regionally defined meniscal tissue
... Knee joints were dissected from 2-3 months old pigs to harvest infrapatellar fat pad and isolate stem cells using established procedures (Buckley et al., 2010). Briefly, tissue was minced and ...
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Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad
... Hoffaʼs fat pad, or infrapatellar fat pad (IFP), has recently emerged as a source of inflammation in the knee OA ...the fat consists of neutral lipids (mostly triacylglycerols, ...
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Association between quantitatively measured infrapatellar fat pad high signal intensity alteration and MRI assessed progression of knee osteoarthritis
... infra-patellar fat pad and comparison between fat- and non-fat-suppressed imaging--Data from the osteoarthritis ...within infrapatellar fat pad on MR images in patients ...
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Expansion in the presence of FGF 2 enhances the functional development of cartilaginous tissues engineered using infrapatellar fat pad derived MSCs
... the infrapatellar fat pad (IFP) and synovium possess significant chondrogenic potential and provide a readily available and clinically feasible source of chondroprogenitor ...
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Coupling freshly isolated CD44+ infrapatellar fat pad derived stromal cells with a tgf β3 eluting cartilage ecm derived scaffold as a single stage strategy for promoting chondrogenesis
... expanded infrapatellar fat pad derived stem cells, or freshly isolated CD44 + stromal cells, it was possible to promote the development of a cartilage-like tissue in ...
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Combining BMP 6, TGF β3 and hydrostatic pressure stimulation enhances the functional development of cartilage tissues engineered using human infrapatellar fat pad derived stem cells
... The objective of this study was to identify a combination of growth factors that could be used with hydrostatic pressure (HP) stimulation to enhance the functional development of cartilaginous grafts engineered using ...
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Arthroscopic Versus Open Resection of Infrapatellar Fat Pad Tumour
... the infrapatellar fat pad, causing chronic anterior knee pain ...the fat pad may be categorized as either diffuse or solitary ...many fat pads which are extrasynovial but ...
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An emerging player in knee osteoarthritis: the infrapatellar fat pad
... The role of inflammation in the development, progression, and clinical features of osteoarthritis has become an area of intense research in recent years. This led to the recognition of synovitis as an important source of ...
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Combining freshly isolated chondroprogenitor cells from the infrapatellar fat pad with a growth factor delivery hydrogel as a putative single stage therapy for articular cartilage repair
... Growth factor delivery systems incorporating chondroprogenitor cells are an attractive potential treatment option for damaged cartilage. The rapid isolation, processing, and implantation of therapeutically relevant ...
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