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inhibitory factor

Macrophage migration inhibitory factor regulating the expression of VEGF C through MAPK signal pathways in breast cancer MCF 7 cell

Macrophage migration inhibitory factor regulating the expression of VEGF C through MAPK signal pathways in breast cancer MCF 7 cell

... Background: As a kind of versatility of cytokines, overexpression of macrophage migration inhibitory factor (MIF) and vascular endothelial growth factor-C (VEGF-C) have been reported in a wide ...

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The potential role of mitochondrial ATP synthase inhibitory factor 1 (IF1) in coronary heart disease: a literature review

The potential role of mitochondrial ATP synthase inhibitory factor 1 (IF1) in coronary heart disease: a literature review

... We carried out an electronic search on electronic scien- tific databases [MEDLINE (1966-14 th August 2016), EMBASE and SCOPUS (1965-14 th August 2016), DARE (1966-14 th August 2016)], and Web of Science Core Collection ...

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Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor

Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor

... is macrophage migration inhibitory factor (MIF). MIF is expressed in human endometrium and has been implicated in numerous reproductive responses, includ- ing ovulation, blastocyst implantation, and embryo- ...

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Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease

Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease

... Autosomal dominant polycystic kidney disease (ADPKD) is characterized by renal cyst formation, inflammation, and fibrosis. Macrophages infiltrate cystic kidneys, but the role of these and other inflammatory factors in ...

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Macrophage migration inhibitory factor enhances influenza-associated mortality in mice

Macrophage migration inhibitory factor enhances influenza-associated mortality in mice

... Influenza-associated mortality continues to occur annually despite available antiviral therapies. New therapies that improve host immunity could reduce influenza virus disease burden. Targeting macrophage migration ...

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Modulation of expression and cellular distribution of p21 by macrophage migration inhibitory factor

Modulation of expression and cellular distribution of p21 by macrophage migration inhibitory factor

... migration inhibitory factor (MIF) is an important contributor to normal cell division as well as oncogene-induced malignant transformation and tumor- igenesis ...

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Role of Macrophage Migration Inhibitory Factor in Otitis Media with Effusion in Adults

Role of Macrophage Migration Inhibitory Factor in Otitis Media with Effusion in Adults

... migration inhibitory factor (MIF) as a factor that inhibits the migration of macro- phages in vitro and as the first cytokine secreted from activated T cells ...

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Macrophage migration inhibitory factor acts as a neurotrophin in the developing inner ear

Macrophage migration inhibitory factor acts as a neurotrophin in the developing inner ear

... migration inhibitory factor (MIF) acts as a neurotrophic factor in the developing zebrafish inner ear (Holmes et ...derived factor(s) (ODF)] to promote the initial outgrowth and survival of ...

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Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma

Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma

... Oesophageal cancer is an aggressive disease with a poor 5 year survival rate of <20% of diagnosed patients. Unfortunately, only 20-30% Oesophageal Adenocarinoma (OAC) patients show a beneficial response to neoadjuvant ...

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25 Years On: A Retrospective on Migration Inhibitory Factor in Tumor Angiogenesis

25 Years On: A Retrospective on Migration Inhibitory Factor in Tumor Angiogenesis

... Twenty-five years ago marked the publication of the first report describing a functional contribution by the cytokine, macrophage migration inhibitory factor (MIF), to tumor-associated angiogenesis and ...

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Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance

Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance

... Radioresistance of EBV-associated nasopharyngeal carcinoma (NPC) is associated with poor prognosis for patients with this form of cancer. Here, we found that NPC patients had increased serum levels of leukemia ...

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Original Article The expression of macrophage migration inhibitory factor in adenomyosis

Original Article The expression of macrophage migration inhibitory factor in adenomyosis

... migration inhibitory factor sup- pressed the migration of macrophages and subsequently as a factor regulating macro- phage host-defence functions [5, ...

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Induction of cytokine expression by leukemia inhibitory factor

Induction of cytokine expression by leukemia inhibitory factor

... Biological effects of cytokines are in part determined by their interactions in the regulation of cytokine production. This study analyzes the effects of leukemia inhibitory factor (LIF) on cytokine ...

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The Role of Macrophage Migration Inhibitory Factor in Alzheimer’s Disease

The Role of Macrophage Migration Inhibitory Factor in Alzheimer’s Disease

... Previous studies have shown that amyloid β protein (A β ), the essential molecule for the formation of toxic oligomers and, subse- quently, Alzheimer plaques, has been associated in vivo with the immune modulator, ...

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Macrophage Migration Inhibitory Factor Promotes Colorectal Cancer

Macrophage Migration Inhibitory Factor Promotes Colorectal Cancer

... A growing body of evidence implicates macrophage migration inhibitory factor (MIF) in tumorigenesis and metastasis. In this study, we investigated whether MIF expression was associated with ...

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Inhibitory roles for SHP 1 and SOCS 3 following pituitary proopiomelanocortin induction by leukemia inhibitory factor

Inhibitory roles for SHP 1 and SOCS 3 following pituitary proopiomelanocortin induction by leukemia inhibitory factor

... Leukemia inhibitory factor (LIF) is a member of the IL-6 cytokine family ...critical factor in the activation of the HPA axis, and the obser- vations that cytokines such as LIF strongly impact this ...

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Macrophage Migration Inhibitory Factor and Autism Spectrum Disorders

Macrophage Migration Inhibitory Factor and Autism Spectrum Disorders

... migration inhibitory factor (MIF) is an upstream regulator of innate immunity that promotes monocyte/macrophage-activation re- sponses by increasing the expression of Toll-like receptors and inhibiting ...

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Chicken cyclophilin A is an inhibitory factor to influenza virus replication

Chicken cyclophilin A is an inhibitory factor to influenza virus replication

... Results: The chCypA gene was isolated and characterized in the present study. It contained an ORF of 498 bp encoding a polypeptide of 165 amino acids with an estimated molecular mass of 17.8 kDa sharing high identity ...

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Analysis of the Activities of the Inflammatory Cytokine Macrophage Migration Inhibitory Factor on Activation of Endoplasmic Reticulum Stress Responses

Analysis of the Activities of the Inflammatory Cytokine Macrophage Migration Inhibitory Factor on Activation of Endoplasmic Reticulum Stress Responses

... The UPR is thought to be activated by the dissociation of BiP from the luminal surface of three major effector proteins, the transcription factor ATF6 and two protein kinases: IRE1α (Calfon et al., 2002) and PERK ...

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Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1

... cell lysates of SH-SY5Y and SH-IF1kd cells, control and exposed to IPC followed by 24h re-oxygenation (Rx) in presence of 3-Methyladenine (3-MA) and Chloroquine ([r] ...

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