Integrin alpha(v)beta(3)
Involvement of integrin alpha V gene expression in human melanoma tumorigenicity
... of alpha v integrins on the tumorigenicity of human ...lack alpha v gene expression and thus fail to express integrin alpha v beta 3 (M21-L ...identical ...
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Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin
... to integrin alpha v beta ...of alpha v beta 3 on the metastatic cells as compared to the parent ...the alpha v beta 3 receptor plays a ...
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Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin alpha v beta 5
... internalization via alpha v beta 5, an effect dependent on the vitronectin in serum. We conclude that pleural mesothelial cells recognize and internalize vitronectin- and serum- coated asbestos via ...
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A concise review of magnetic resonance molecular imaging of tumor angiogenesis by targeting integrin αvβ3 with magnetic probes
... molecule integrin αvβ3 is a specific marker of angiogenesis, which is highly expressed on activated and proliferating endothelial cells, but generally not on quiescent endothelial ...of integrin αvβ3, ...
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Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis
... the integrin, Nanotetrac does block the proliferative and proangiogenic effects of T 4 and 3,5,3 ′ -triiodo-L-thyronine (T 3 ) initiated at the cell ...the integrin on transcription of genes integral ...
6
Insulin like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo
... for a total of 7 to 9 d, at which time the embryos were killed. Tumors that formed at the primary site were excised, trimmed free of sur- rounding CAM tissue, and weights were determined. Pulmonary me- tastasis was ...
10
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis
... the integrin alpha v/beta 3 has been reported as a mediator of anchorage independence [21], and its expression has been associated with an aggressive form of disease in different human ...
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Integrin α<sub>v</sub>β<sub>3</sub>-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy
... cancers, integrin α v β 3 is a crucial cell adhesion and signaling molecule that promotes the proliferation, survival, drug-resistant properties, and metastatic potential of cancer ...of ...
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Exploration of peptide T7 and its derivative as integrin αvβ3-targeted imaging agents
... To determine the integrin α v β 3 expression levels in different cell lines, a flow cytometry assay was performed. Briefly, cells were collected and washed with phosphate-buffered saline (PBS) ...
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Integrin Alpha V Beta 3 Matrix Metalloproteinase 2 (MMP 2), Cross Talk
... breast cancer cases of different stages from the institutional hospital catchment area. Patients were offered treatment according to the stage of the disease, either surgery followed by chemotherapy and ± Radiotherapy or ...
10
Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells to assess the effect of chondrogenic differentiation on response to interleukin-1β treatment
... Amyloid- beta precursor protein; ASPN: Asporin; BM: Bone marrow; CM: Chondrogenic media; CMIL: Chondrogenic media with IL-1 β ; COMP: Cartilage oligomeric matrix protein; CRTAC1: Cartilage acidic protein 1; CRTAP: ...
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Insilico and Electron Microscope Study about Attachment of Mesenchymal Stem Cell Derived from Stromal Vascular Fraction to Scaffold (Bovine Bone Cancellous, Hydroxyapatite-Calcium Sulphate, Calcium Phosphate)
... was Integrin Alpha V to Hydroxyapatite which need a total energy of ...and Integrin Beta 2 to Hydroxyapatite which need a total energy of ...
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Interleukin-8 promotes integrin β3 upregulation and cell invasion through PI3K/Akt pathway in hepatocellular carcinoma
... 8]. Integrin α v β 3, as an important cell surface adhesion molecule, has also been reported to be overexpressed in cancer tissues and mediate the invasion and metastasis of HCC cells [13 – ...and ...
10
Clinicopathological and prognostic values of fibronectin and integrin αvβ3 expression in primary osteosarcoma
... the integrin family, integrin αvβ3 specifically binds to FN with high affinity ...[9]. Integrin αvβ3 expression is strongly increased in tumor cells, with a prominent role as a pro-angiogenic factor ...
12
Nanobiomechanical Properties of Microtubules
... in alpha-beta, beta-alpha, alpha- alpha and beta-beta dimers was calculated using the molecular dynamic simulation and GROMACS software ...
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α<sub>v</sub>β<sub>3</sub> integrin-targeted micellar mertansine prodrug effectively inhibits triple-negative breast cancer in vivo
... α v β 3 integrin overexpressing MDA-MB-231 TNBC xenografts in nude mice, resulting in potent tumor growth ...inhibition. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) ...
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Transforming growth factor-beta receptor signalling is modulated by integrin-linked kinase
... for integrin β1, results in abnormal hair follicle morphogenesis and severe blistering due to abnormal basement membrane assembly (Brakebusch et ...β1 integrin gene inactivation results in perinatal death ...
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Treatment of marrow stroma with interferon alpha restores normal beta 1 integrin dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors Role of MIP 1 alpha
... modulating beta 1 integrin receptor ...that alpha 4 beta 1 and alpha 5 beta 1 integrin receptors were involved in the enhanced adhesion of CML progenitors, suggesting that ...
10
Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities
... A Cyr61 promoter-driven reporter gene expressed in transgenic mice further detected Cyr61 gene expression in a wide range of other tissues including the respiratory system, the embryonic skeletal system including the ...
13
Estimates for the commutators of operator \(V^{\alpha }\nabla ( \Delta +V)^{ \beta }\)
... operator have appeared (see [1–5]). In recent years, some researchers have studied the boundedness of the commutators generated by the operators associated with L and the BMO type space (see [6–9]). In this paper, we ...
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