interacting protein
Variants in the Toll interacting protein gene are associated with susceptibility to sepsis in the Chinese Han population
... Toll-like receptors (TLRs), a family of immune recep- tors, were recently reported to be involved in the recog- nition of pathogen-associated molecular patterns and the initiation of host immune responses [11]. In ...
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Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer
... activator protein 1 (Fos/Jun) (AP-1) and specificity protein 1 (SP-1), and elevates hypoxia inducible factor 1α (HIF-1α) protein levels, which in turn influence vascular endothelial growth factor ...
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<p>Receptor-Interacting Protein Kinase 1 Promotes Cholangiocarcinoma Proliferation And Lymphangiogenesis Through The Activation Protein 1 Pathway</p>
... Receptor-interacting protein kinase 1 (RIPK1) is an critical upstream regulator of diverse cell signaling path- ways, including TNF- α , IL-6 and TLR3/4 in fl ammatory ...activation protein 1 (AP-1) – ...
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Thioredoxin interacting protein (TXNIP) is an independent risk stratifier for breast ductal carcinoma in situ
... thioredoxin (TRX), thioredoxin interacting protein (TXNIP) has potent growth suppressive, metastasis inhibitory and pro-apoptotic functions (12). Loss of TXNIP expression was reported to be associated with ...
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The novel Smad interacting protein Smicl regulates Chordin expression in the Xenopus embryo
... Fig. 1. Smicl is a Smad-interacting protein that is expressed maternally and then zygotically during Xenopus development. (A) Amino acid sequence of XtSmicl, a novel Smad interacting protein. ...
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Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B
... Munc18c is a novel PTP1B substrate as evidenced by several supporting observations. Mass spectrometry of adipocytes expressing the substrate-trapping PTP1B mu- tant identified Munc18c as a PTP1B-interacting ...
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The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis
... TRAF-interacting protein (TRAIP) is an E3 ubiquitin ligase required for cell ...and protein-DNA complex formation in gel shift ...and protein was regulated by the cell cycle with a peak in ...
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Filamin A interacting protein 1-like expression inhibits progression in colorectal cancer
... Filamin A interacting protein 1-like (FILIP1L) expression, which is decreased in various cancers, may inhibit carcinogenesis. In this study, we evaluated the effects of FILIP1L on oncogenic behavior and ...
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Herpes Simplex Virus 1 Small Capsomere-Interacting Protein VP26 Regulates Nucleocapsid Maturation
... ABSTRACT VP26 is a herpes simplex virus 1 (HSV-1) small capsomere-interacting protein. In this study, we investigated the function of VP26 in HSV-1-infected cells with the following results. (i) The VP26 ...
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Association of toll-interacting protein gene polymorphisms with atopic dermatitis
... Toll- interacting protein (TOLLIP) is an adaptor protein that acts as an inhibitory factor in the TLR-signalling cascade ...adaptor protein (TIRAP) through inhibition of Interleukin-1 receptor ...
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Targeting JNK-interacting protein 1(JIP1) sensitises osteosarcoma to doxorubicin
... Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents. Despite aggressive therapy, survival outcomes remain unsatisfactory, especially for patients with metastatic disease or ...
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Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation
... active protein that is important for maintaining the reducing milieu of the cell, in part by reducing protein disulfide bonds that occur in response to oxidative pro- ...thioredoxin interacting ...
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Crystallization of an engineered RUN domain of Rab6 interacting protein 1/DENND5
... Rab6-interacting protein 1 (R6IP1) required co-expression with Rab6, as attempts to solubly express the effector alone were ...domain-containing protein 5 (DENND5) and is expressed as two isoforms, ...
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Huntingtin interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival
... Huntingtin-interacting protein 1 (HIP1) is a cofactor in clathrin-mediated vesicle trafficking. It was first implicated in cancer biology as part of a chromosomal translocation in leukemia. Here we report ...
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Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer
... ZW10 interacting protein; sclc, small-cell lung cancer; aDc, adenocarcinoma; scc, squamous cell carcinoma; lcc, large-cell carcinoma; lcne, large-cell neuroendocrine tumor; Bas, basaloid; carci, carcinoid ...
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Identification of a TRBD zinc finger interacting protein in Giardia duodenalis and its regulation of telomerase
... The protein p80 in mammalian cells is related to telomerase activity in vivo ...hTERT protein level reportedly increases significantly after gene silencing of PCDH10, indicating that PCDH10 likely affects ...
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Restoration of Silencing in Saccharomyces cerevisiae by Tethering of a Novel Sir2-Interacting Protein, Esc8
... Esc8p and Esc2p both interact with Sir2p: To restore TPE in strain GCY212 (SIR2-143), it is sufficient to tether Sir2-143p to the telomere by fusing it to the Gbd (Cup- erus et al. 2000). It is therefore possible that ...
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Regulation of vascular endothelial growth factor expression by homeodomain-interacting protein kinase-2
... Transient transfection was carried out using the N,N-bis- (2-hydroxyethyl)-2-amino-ethanesulphonic acid-buff- ered saline (BBS) version of the calcium phosphate proce- dure [23]. The amount of plasmid DNA was equalized ...
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Regulation of ocular lens development by Smad interacting protein 1 involving Foxe3 activation
... Loss of Foxe3 activation in Sip1-defective lens A persistent lens stalk is called Peter’s anomaly in human congenital diseases, and accompanies the inactivation of the transcription factor Foxe3 (Blixt et al., 2000; ...
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Poly(C)-Binding Protein 1, a Novel Npro-Interacting Protein Involved in Classical Swine Fever Virus Growth
... were transiently transfected with 3⫻Flag-PCBP1 and subse- quently infected with CSFV. In these cells, 3 ⫻ Flag-PCBP1 could be readily detected, and the expression of N pro protein was in- creased (Fig. 5A and C). ...
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