intercellular adhesion molecule
Role of the intercellular adhesion molecule 1(ICAM 1) in endotoxin induced pneumonia evaluated using ICAM 1 antisense oligonucleotides, anti ICAM 1 monoclonal antibodies, and ICAM 1 mutant mice
... to intercellular adhesion molecule-1 (ICAM-1) to inhibit endotoxin-induced upregulation of ICAM-1 and neutrophil emigration and compared the apparent role of ICAM-1 when examined using antisense ...
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Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target
... To identify the specific targets regulated by the p53 protein, we transfected human osteosarcoma cell line Saos-2 with adenoviral vectors expressing the p53 family members or LacZ as a control and compared mRNA ...
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Intercellular adhesion molecule 1 deficient mice are protected against ischemic renal injury
... Studies in the rat have pointed to a role for intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of acute tubular necrosis. These studies used antibodies, which may have nonspecific ...
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Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) – A Receptor Associated with Severe Plasmodium falciparum Malaria
... Intercellular adhesion molecule 1 (ICAM-1) is a membrane-bound glycoprotein expressed on endothelial cells and cells of the immune ...mediates adhesion and migration of leucocytes, and is ...
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Interactions of leukocyte integrins with intercellular adhesion molecule 1 in the production of inflammatory vascular injury in vivo The Shwartzman reaction revisited
... deposition, and massive extravasation of erythrocytes. Hemorrhage in these Shwartzman- like lesions was quantitated by 99mTc-labeled autologous erythrocytes. Inhibition of the hemorrhagic response was obtained with mAb ...
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A functional integrin ligand on the surface of platelets: intercellular adhesion molecule 2
... intercellular adhesion molecular-2 (ICAM-2) (CD102), and lack of expression of other beta 2-integrin ligands, ICAM-1 (CD54) and ICAM-3 (CD50), on the surface of resting and stimulated ...In adhesion ...
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The Serum Changes of Neuron-Specific Enolase and Intercellular Adhesion Molecule-1 in Patients With Diffuse Axonal Injury Following Progesterone Administration: A Randomized Clinical Trial
... The effect of progesterone on the serum level of ICAM- 1 in the present study is consistent with studies that the ICAM-1 reduced in rats with brain injury following pro- gesterone (16, 17). Also, progesterone decreased ...
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Expression and partial purification of recombinant bovine intercellular adhesion molecule 1
... The truncated construct of A6 was used for recombinant bovine ICAM-1 antibody production, and testing of biological activity in vitro because it had already been produced in abundance, a[r] ...
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Effects of inflammatory cytokine IL 27 on the activation of fibroblast like synoviocytes in rheumatoid arthritis
... ICAM: intercellular adhesion molecule; IFN: interferon; IL: interleukin; JAK: Janus kinase; JNK: c-Jun amino-terminal kinase; MAPK: mito- gen activated protein kinases; MFI: mean fluorescence ...
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The role of cytokines, adhesion molecules, and chemokines in interleukin 2 induced lymphocytic infiltration in C57BL/6 mice
... increased intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) expression in association with this organ-specific lymphocytic ...
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The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation
... TNF-α-induced adhesion and migration of human umbilical vein endothelial cells (HUVECs) by inhibiting the expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell ...
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Marked synergism between tumor necrosis factor alpha and interferon gamma in regulation of keratinocyte derived adhesion molecules and chemotactic factors
... and intercellular adhesion ...to adhesion or chemotaxis of inflammatory cells) failed to induce any of the ...and adhesion molecule ...
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Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis
... sion molecule [VCAM]-1, intercellular adhesion molecule [ICAM]-1, and endothelial leucocyte adhesion molecule [ELAM]-1 [or selectin]) ...circulating adhesion molecules are ...
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E-selectin and vascular cell adhesion molecule-1 as biomarkers of 3-month outcome in cerebrovascular diseases
... Four CAMs were quantified in each blood sample: E- selectin, P-selectin glycoprotein ligand-1 (P-selectin), intercellular adhesion molecule-1 (ICAM-1), and VCAM-1. The levels of six other biomarkers ...
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Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin dependent diabetes mellitus
... and adhesion molecules of vascular endothelium and studied by immunofluorescence microscopy, and peripheral blood mononuclear cells were phenotyped using flow ...expressed intercellular adhesion ...
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Interferon gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts
... molecules, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 compared to normal or isografted ...leukocyte adhesion molecules may contribute to the lack of ...
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Young Hispanics at risk of type 2 diabetes display endothelial activation, subclinical inflammation and alterations of coagulation and fibrinolysis
... uble intercellular adhesion molecule-1 [sICAM-1] and soluble vascular adhesion molecule [sVCAM]), disturbed coagulation/fibrinolysis (tissue-type plaminogen activa- tor [tPA] and ...
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Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion In Vitro
... by adhesion molecules on lymphocytes, called homing receptors, and their corresponding ligands on endothelial cells, called vascular addressins ...cell adhesion molecules (ECAMs) in the intestines of both ...
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Effect of gold sodium thiomalate and its thiomalate component on the in vitro expression of endothelial cell adhesion molecules
... on adhesion molecule protein and mRNA expression in cultured human endothelial ...cell adhesion molecule-1 and E-selectin but not intercellular adhesion molecule-1 on ...
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A prospective study of endothelial activation biomarkers, including plasma angiopoietin 1 and angiopoietin 2, in Kenyan women initiating antiretroviral therapy
... HIV-1-induced inflammation has been linked to in- creased biomarkers of endothelial activation, including soluble intercellular adhesion molecule-1 (ICAM-1), vas- cular adhesion ...
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