interleukin-1beta (IL-1beta)
Production of interleukin 1beta by human hematopoietic progenitor cells
... of interleukin 1beta (IL-1beta) by human hematopoietic stem/progenitor cells was studied to explore the concept that these cells are not merely responders to stimuli from their ...
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Effects of sesamin on chondroitin sulfate proteoglycan synthesis induced by interleukin 1beta in human chondrocytes
... reports. IL-1β induces downregulation of aggrecan and xylosyltransferase-1 expression while it upregulates MMP-13 and ADAMTs expression [14–16, 19, ...on IL-1β-induced porcine cartilage explants have shown ...
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Differential expression and upregulation of interleukin 1alpha, interleukin 1beta and interleukin 6 by freshly isolated human small intestinal epithelial cells
... express IL-6 are comparable with those of monocytes taken from blood of the same ...express IL-6, it is possible to induce the ‘in vitro’ expression of IL-6 in other SIEC by treatment for 4 h with ...
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Epigallocatechin 3 gallate suppresses the global interleukin 1beta induced inflammatory response in human chondrocytes
... with IL-1 [56,57], but their suppression by EGCG has not been previously described in OA ...in IL-1b-stimulated RA-synovial fibroblasts ...in IL-1b-stimulated OA ...
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Mechanisms of impaired beta adrenoceptor induced airway relaxation by interleukin 1beta in vivo in the rat
... group compared with control (Fig. 6, top). In the absence of IBMX, the basal cAMP accumulation and the isoproterenol- stimulated cAMP response did not differ significantly between control and IL-1b–treated rats ...
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Leptin or troglitazone induced lipopenia protects islets from interleukin 1beta cytotoxicity
... like IL-1 b , long-chain fatty ac- ids (FFA) also upregulate iNOS expression and enhance NO generation in rat islets ...of IL-1 b and that islet tissue lipopenia might protect b cells against NO- mediated ...
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1,25 Dihydroxyvitamin D3 and its analogues inhibit acute myelogenous leukemia progenitor proliferation by suppressing interleukin 1beta production
... to IL-1b by partial reversal of growth inhibition ...of IL-1b ...to IL-1b, a com- bination of MC1301 and an inhibitor of IL-1b action (IL-1 re- ceptor antagonist or soluble IL-1 ...
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Bradykinin stimulates NF kappaB activation and interleukin 1beta gene expression in cultured human fibroblasts
... BK-induced IL-1 b synthesis, results from Northern blot and nuclear run-on assays suggested that BK acted primarily at the transcription level which led to the accumulation of IL-1 b message in stimulated ...
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Macrophage derived interleukin 1beta promotes human breast cancer cell migration and lymphatic adhesion in vitro
... binant IL-1β, tumour cell adhesion to blood and lym- phatic endothelial cell monolayers increased; however, a larger increase was observed in cells of lymphatic ...with IL-1β and added to unstimulated ...
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Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle
... particularly IL-1 b , may be significantly in- volved in mediating both the proinflammatory processes and changes in airway responsiveness that characterize the atopic/ asthmatic ...of IL-1 b in inducing ...
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Systemic autoimmune disease in asbestosis rapidly responding to anti interleukin 1beta antibody canakinumab: a case report
... of interleukin-1beta (IL-1beta) in the pathogenesis of asbestosis and its systemic autoimmune manifestations has been reported ...of IL-1beta by alveolar macrophages through the ...
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Effect of Interleukin 1Beta (IL 1β) on the Cortical Neurons Survival and Neurites Outgrowth
... [9]. IL-1 β is a pro-inflammatory cytokine that exerts an important role in developing brains as a maintenance and growth-promoting factor [10] [11] and in migration of cortical neurons ...[12]. IL-1 β is ...
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Taurolidine reduces the tumor stimulating cytokine interleukin 1beta in patients with resectable gastrointestinal cancer: a multicentre prospective randomized trial
... samples IL-1β val- ues were lower in the TRD group (shown in Figure 3; T3 measurement p = ...with IL-6 (shown in Table 3a; T3 p = ...with IL-10 (in T5, p < ...other Interleukin values in ...
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Inhibition of interleukin 1beta stimulated dedifferentiation of chondrocytes via controlled release of CrmA from hyaluronic acid chitosan microspheres
... the IL-1β–induced breakdown of type II collagen and proteoglycan in OA cartilage by decreasing the secretion of IL-1β, leading to the deceleration of OA ...of IL-1β and collagen I decreased, while ...
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Evaluation of Brainstem auditory evoked potential and serum Interleukin-1beta levels in patients with generalized tonic clonic seizures
... of IL-1β during epileptogenesis contributing to neuronal injury suggests that IL-1 β activated pathways play a vital role in the genesis of spontaneous seizures, thus raising the possibility of using ...
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A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL 1beta, TNF alpha and IL 6 Challenges in C57BL/6 Mice
... that IL-6 had no effect on most measures, there was some concern that the doses used for this cytokine were simply below those required for biological ...of IL-6 in the hepatic acute phase response [37,38], ...
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Interleukin 1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase 2 during early mammary tumourigenesis
... in IL-1 within the microenvironment, which can then act on the epithe- lial cells to promote ...exogenous IL-1 on epithelial cells to mimic the increased levels of IL-1 within the ...with ...
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Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL 1beta induced cytotoxicity and reduces nitric oxide production
... to IL-1 b was observed in MnSOD-overexpressing b G I/17 cells relative to control clones transfected with the empty vector ...during IL-1 b treatment was similar in INS-1 and b G I/17 cells and their ...
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Differential expression of pro inflammatory cytokines IL 15Ralpha, IL 15, IL 6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients
... the IL-15 protein are found in the synovial fluid of early knee OA patients when com- pared to end-stage OA ...serum IL-15 levels are associated with severity of pain in patients with knee OA; this suggests ...
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Original Article Shikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathway
... osteoarthritis. IL-1β is generally served as an agent that induces chondrocyte ...on interleukin-1beta (IL-1β)- induced chondrocyte apoptosis and the potential molecular ...by IL-1β (10 ...
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