Intestinal epithelium stem cell
Porcine Intestinal Enteroids: a New Model for Studying Enteric Coronavirus Porcine Epidemic Diarrhea Virus Infection and the Host Innate Response
... nonporcine intestinal epithelial cells and thus not the ideal in vitro cellular models for studying the interaction between PEDV infection and the host response due to interspecific ...porcine intestinal ...
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Large Animal Models to Study Intestinal Stem Cell Mediated Repair.
... of epithelium at the villus tip, 3 indicates loss of epithelium from 50 to 75% of the villus, 4 indicates loss of epithelium from the entire villus, and 5 indicates loss of villus and crypt ...
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PerezChanona_unc_0153D_15015.pdf
... the intestinal epithelium, microbial signals such as LPS (Perez-Chanona & Jobin, personal observation) and butyrate increase NOD2 expression 32,40 ...Lgr5+ stem cells express five times the level ...
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Nipped A regulates intestinal stem cell proliferation in Drosophila
... Loss of tissue integrity and function is a detrimental process affecting the health of individuals during aging. In Drosophila, the aging midgut epithelium is characterized by ISC hyperproliferation accompanied by ...
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The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis
... Recombinant intestinal organ culture studies using transgenic ...into epithelium (Ep) and non-epithelial tissues (non-Ep), which consists of mainly the connective tissue underlying the ...Tg ...
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Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling
... 2015). Intestinal stem cells differentiate into two primary cell types: absorptive enterocytes and secretory ...specific intestinal cell lineages are currently under investigation, but ...
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Abstract: Recent technical advances in the stem cell field have enabled the in vitro generation of
... the epithelium makes little, if any, Wnt ...by intestinal subepithelial myofibroblasts ...Paneth cell-derived Wnt3 is necessary for in vitro intestinal epithelial ...
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Distinct SOX9 Levels.pdf
... adult intestinal epithelium (now termed Sox9 LOW and Sox9 HIGH ...the cell +4-6 position of the crypt and also sporadically throughout the villus ...multipotent stem cell ...IEC-18 ...
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Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling
... 2015). Intestinal stem cells differentiate into two primary cell types: absorptive enterocytes and secretory ...specific intestinal cell lineages are currently under investigation, but ...
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BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury
... gastro- intestinal injury, resulting in diarrhea, dehydration, sepsis, and intestinal bleeding with eventual mortality within 10 to 15 days post-exposure ...of intestinal stem cells (ISC) [2, ...
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EGF signaling regulates the proliferation of intestinal stem cells in Drosophila
... Many stem cell populations are regulated by their microenvironments, and larval ISC progenitors are regulated by a transient niche (Mathur et ...associated cell population within the ...
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PubMedCentral-PMC5314158.pdf
... the intestinal epithelium are not fully ...control intestinal epithelial stem cell (IESC) prolifer- ation in part through microRNAs ...tinct cell types of the mouse jejunal ...
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Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-Deficient Murine Epithelium
... We next wanted to test if an expected age-related increase in mutation burden could be detected using the above method. Therefore, 744 crypts were isolated from five wild-type mice at different ages (age range 76–735 ...
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Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase 1
... of cell types ...different cell types, and also make different contributions to eicosanoid produc- tion in the same cell type under different ...epithelial cell proliferation, wound heal- ing, ...
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Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis
... stratified epithelium of the gastrointestinal tract, the basal-most layer contains stem and transit-amplifying cells, which together provide the mitotic ...the cell cycle and differentiate (for a ...
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Ion channel TRPV1 dependent activation of PTP1B suppresses EGFR associated intestinal tumorigenesis
... mammalian intestinal epithelium reveals a complex inter- play among intestinal stem cell (ISC) self-renewal in the crypts of Lieberkühn, progenitor cell proliferation, ...
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New insights into the unfolded protein response in stem cells
... [128]. Cell surface levels of GRP78 are high in stem cells and tumor ...cancer stem cell proliferation and colony formation, inhibiting self- renewal and multidifferentiation abilities, and ...
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A strategy to ensure safety of stem cell-derived retinal pigment epithelium cells
... pluripotent stem cells towards RPE The protocol for differentiation of hESC or hiPSC towards RPE has been described elsewhere ...tent stem cells are seeded on Matrigel (Corning) coated surfaces and on day 2 ...
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The deubiquitinase USP54 is overexpressed in colorectal cancer stem cells and promotes intestinal tumorigenesis
... obtain intestinal stem cell (ISC)-enriched cell populations ...in intestinal cells with stem properties (Figure ...the stem characteristics of both ISCs and ...
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Interactions between commensal obligate anaerobes and human intestinal cells : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Manawatu, New Zealand
... Caco-2 cells were cultured on Transwell inserts in a co-culture chamber in an anaerobic environment for 12 hours. Immediately after removing the inserts from the chamber, the cells were fixed by immersing the Caco-2 ...
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