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INTESTINAL PERMEABILITY

Predicting the Bioequivalence of Ciprofloxacin HCL Tablet Brands Using In Vitro Dissolution and Rat Intestinal Permeability Tests

Predicting the Bioequivalence of Ciprofloxacin HCL Tablet Brands Using In Vitro Dissolution and Rat Intestinal Permeability Tests

... The experiment was carried out as described in the literature [15-18] with appropriate modification. Prior to intestinal permeability test, it was necessary to carry out standard calibration curve of the ...

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Intestinal permeability studies for piperaquine from dihydroartemisinin—piperaquine antimalarial product in the presence of lamivudine

Intestinal permeability studies for piperaquine from dihydroartemisinin—piperaquine antimalarial product in the presence of lamivudine

... high intestinal permeability indicating that LMV readily crosses the ...across intestinal epithelium and this is dependent on many pharmacokinetic characteristics such as lipophilicity, molecular ...

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Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability

Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability

... the permeability of sulpiride by incorporation into a SLN formu- lation, it can be said that F7 is the optimum formulation that combines many positive attributes, including a relatively low particle size and ...

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Direct Implementation of Intestinal Permeability Test in NMR Metabolomics for Simultaneous Biomarker Discovery—A Feasibility Study in a Preterm Piglet Model

Direct Implementation of Intestinal Permeability Test in NMR Metabolomics for Simultaneous Biomarker Discovery—A Feasibility Study in a Preterm Piglet Model

... Abstract: Measurement of intestinal permeability (IP) is often used in the examination of inflammatory gastrointestinal disorders. IP can be assessed by measurement of urinary recovery of ingested ...

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Maturation of gastric electrical activity, gastric emptying and intestinal permeability in preterm newborns during the first month of life

Maturation of gastric electrical activity, gastric emptying and intestinal permeability in preterm newborns during the first month of life

... and intestinal permeability in preterm ...nal permeability in a time series in order to account for the effect of the different physiological variables over ...

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Effect of prebiotic intake on gut microbiota, intestinal permeability and glycemic control in children with type 1 diabetes: study protocol for a randomized controlled trial

Effect of prebiotic intake on gut microbiota, intestinal permeability and glycemic control in children with type 1 diabetes: study protocol for a randomized controlled trial

... Intestinal permeability will be assessed at baseline, 3 months and 6 months. Participants will consume a regular evening meal and then 3 hours later, prior to bedtime, drink a solution containing lactulose ...

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Are self-reported gastrointestinal symptoms among older adults associated with increased intestinal permeability and psychological distress?

Are self-reported gastrointestinal symptoms among older adults associated with increased intestinal permeability and psychological distress?

... Increased intestinal permeability is a hallmark of many GI diseases [12–14] but has not been investigated in older adults who self-report GI ...The intestinal epithelium is the major interface with ...

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Knockout of MIMP protein in lactobacillus plantarumlost its regulation of intestinal permeability on NCM460 epithelial cells through the zonulin pathway

Knockout of MIMP protein in lactobacillus plantarumlost its regulation of intestinal permeability on NCM460 epithelial cells through the zonulin pathway

... gut permeability in coeliac disease [20] and type 1diabetes mellitus ...of intestinal permeability ...on intestinal permeability has still not been ...on intestinal ...

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Quantitation of small intestinal permeability during normal human drug absorption

Quantitation of small intestinal permeability during normal human drug absorption

... the intestinal permeability of drugs is the Caco-2 cell culture ...AM permeability with the Caco-2 permeability is inexact because of the variety of tech- niques that have been used for ...

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The Ussing chamber system for measuring intestinal permeability in health and disease

The Ussing chamber system for measuring intestinal permeability in health and disease

... measure intestinal permeability of mouse and human colonic samples ex vivo using the Ussing chamber ...system. Intestinal epithelial bar- rier function is crucial for maintaining a symbiotic rela- ...

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Intestinal permeability – a new target for disease prevention and therapy

Intestinal permeability – a new target for disease prevention and therapy

... increased intestinal motility, the administered dose should be kept as low as ...possible. Permeability assays are usually useful only for assessing small intestinal perme- ability, since lactulose ...

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Original Article Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis

Original Article Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis

... Gut microbiota forms an integral biological bar- rier in the maintenance of intestinal homeosta- sis. The microbiot performs defensive function supported by the synergistic commensal re- lationship, including ...

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Mast Cell Corticotropin-Releasing Factor Receptor Subtypes, CRF1 and CRF2, Differentially Modulate Stress-induced Intestinal Permeability.

Mast Cell Corticotropin-Releasing Factor Receptor Subtypes, CRF1 and CRF2, Differentially Modulate Stress-induced Intestinal Permeability.

... increase intestinal permeability, an effect that is completely prevented by mast cell stabilization ...regulating intestinal barrier function during the stress response is yet to be elucidated ...

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Intestinal permeability in a patient with liver cirrhosis

Intestinal permeability in a patient with liver cirrhosis

... the intestinal lumen to the mesenteric nodes, and systemic circulation, resulting in the development of severe complications related to high mortality ...The intestinal barrier is a structure with a physi- ...

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Intestinal permeability in children/adolescents with functional dyspepsia

Intestinal permeability in children/adolescents with functional dyspepsia

... The intestinal barrier is highly regulated by immune factors and increased permeability has been seen in other conditions associated with inflammation, such as Crohn’s disease and Celiac disease ...between ...

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Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

... The acute form of the disease is mostly observed within the first 100 days post-transplantion, and is a major challenge to transplants owing to associated mor- bidity and mortality [1,5]. Classically, acute GvHD is ...

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Comparison of Two Commercial Preparations of Curcumin using the Caco-2 in vitro Assay of Human Intestinal Permeability

← Return to Article Details Comparison of Two Commercial Preparations of Curcumin using the Caco-2 in vitro Assay of Human Intestinal Permeability

... compare permeability and reflux, namely ranitidine (low permeability), talinolol (highly effluxed), talinolol with 25 µM verapamil (inhibition of efflux), and warfarin (high ...

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The role of CB1 in intestinal permeability and inflammation

The role of CB1 in intestinal permeability and inflammation

... the hypotensive and vasodilator effects of lipopolysaccharide (LPS) in rats, and to protect the rat liver from endotoxaemia and prolonged the survival of rats with severe acute pancreatitis (20–22). However, several ...

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T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+ ATPase

T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+ ATPase

... Diarrhea is a common clinical feature of immune- mediated bowel dysfunction. Disordered immune cell activation leads to bowel dysfunction via multiple pathways. In disorders associated with cellular inflammation, ...

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The protective effect of VSL#3 on intestinal permeability in a rat model of alcoholic intestinal injury

The protective effect of VSL#3 on intestinal permeability in a rat model of alcoholic intestinal injury

... in which WT rats were fed with VSL#3 before adminis- tration of alcohol. Our results demonstrate that expres- sion of the tight junction proteins ZO-1 and occludin was decreased in acute alcohol liver disease, and VSL#3 ...

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