Intra-articular injection
Comparison of the clinical effect of intra-articular injection of platelet-rich plasma and methylprednisolone in primary osteoarthritis of knee: a randomized controlled trial
... precautions intra-articular injection knee joint with 6 ml of activated PRP was performed through a marked point inferior to the patella and lateral to the patellar tendon in a 90˚ flexed knee using ...
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Local intra articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis
... on articular cartilage after OA, we investigated chondrocyte ...the intra-articular injection of rapamycin reduced the hypertrophic changes in the articular cartilage in this ...
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Intra articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthritis
... that intra- articular adenoviral mediated gene transfer of TRAIL into inflamed rabbit knees in vivo resulted in extensive apoptosis, suggesting that the proliferating synoviocytes in vivo are more ...
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Safety, tolerability, clinical, and joint structural outcomes of a single intra articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double blind randomised trial
... The present study has limitations. It is a pilot phase Ib/IIa randomised controlled trial with the primary aim being to determine the safety and tolerability of a single intra-articular injection of ...
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Evaluation of Delayed Effect of Intra-Articular Injection of Cefazolin, Gentamicin and Vancomycin on Articular Cartilage: an Experimental Study in Rabbits
... of intra-articular injection of cefazolin, gentamicin and vancomycin on articular ...on articular cartilage and this effect may be manifested as a delayed phenomenon due to changes in ...
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Intra-articular injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in cementless total knee arthroplasty
... retrograde intra-articular injection of TA via the drain at the end of the operation followed by clamping the drain for 1 h (n = 70) (from January 2010 through March ...
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Intra articular injection of mono iodoacetate induces osteoarthritis of the hip in rats
... However, the mechanism for hip pain has been un- clear because of a lack of experimental animal models. For knee OA, several animal models have been proposed, such as the anterior cruciate ligament transection model [8], ...
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Repeated intra-articular injection of allogeneic mesenchymal stem cells causes an adverse response compared to autologous cells in the equine model
... of intra-articular ...that injection of MSCs contain- ing FBS contamination would have the greatest effect on clinical ...second intra-articular injection, and the two horses ...
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INTRA ARTICULAR INJECTION OF PLATELET RICH PLASMA IN KNEE OSTEOARTHRITIS CLINICAL EVALUATION
... on intra articular PRP injection of primary knee osteoarthritis showing its advantage and ...plasma injection treatment and follow up for at least six ...steroid injection, blood ...
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Repair of articular cartilage defects with intra articular injection of autologous rabbit synovial fluid derived mesenchymal stem cells
... After 8 and 12 weeks of intra-articular injection, all rab- bits were sacrificed and the operated distal femur con- dyles were harvested. The specimens were fixed with 10% formalin solution ...
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Effects of a Single Intra-Articular Injection of a Microsphere-Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study
... In summary, this randomized double-blinded trial demonstrated sustained and clinically meaningful reductions in pain in knee osteoarthritis following a single intra-articular injection o[r] ...
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Intra articular injection of collagenase in the knee of rats as an alternative model to study nociception associated with osteoarthritis
... a significant correlation between nociception induced by movement and loading on the joint and the degree of ar- ticular changes was also evident with the 500 U dose. The Knee-Bend test highly correlated with both the ...
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Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection
... after intra-articular (IA) injection, by forming micrometer-sized electrostatic clusters with endogenous hyaluronic acid (HA) in the synovial ...IA injection of the cationic NPs were ,70% ...
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Intra articular injection of xanthan gum: A potential therapy for osteoarthritis
... IA injection of XG with high viscosity is considered to be able to coat the receptor endings of the joint pain fi- bers, decrease their sensitization to inflammatory media- tors, entrapment of endogenous pain ...
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Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis
... OA. Intra-articular injection of APETx2, a specific blocker of ASIC3, had an inhibitory effect on weight distribution asymmetry and secondary hyperalgesia by attenuating ASIC3 upregulation in knee ...
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Analgesic effect of intra-articular ropivacaine injection after arthroscopic surgery on the shoulder joint in dogs
... ABSTRACT: Shoulder joint disorders are a major cause of forelimb lameness in dogs, and osteochondrosis, degenerative joint disease, and bicipital tenosynovitis are common joint disorders that have been reported in dogs. ...
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Accuracy of injection and short term pain relief following intra articular corticosteroid injection in knee osteoarthritis – an observational study
... precise intra- vs extra-knee joint cavity placement, the question remains as to whether an injection close to the synovium ...accurate intra-articular injection is neither a guarantor ...
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Original Article Clinical observation of pulsed radiofrequency in treatment of knee osteoarthritis
... chronic articular pain on knee, dys- function, depression mood, and decreased quality of ...medication, intra-articular cortico- steroid injections (IACIs), and intra-articular ...
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RESEARCH ARTICLE Localized Injection of Streptomycin, Kenacort and Lidocaine combination for Symptomatic Pain Management of Knee Osteoarthritis
... this injection therapy. Intra-articular injection of steroids are thought to be linked to the destruction of the knee, but there is no strong evidence which supports the progression of knee ...
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Differential contributions of peripheral and central mechanisms to pain in a rodent model of osteoarthritis
... to intra-articular ...post injection. Following intra-articular injection of MIA, pain behaviour was assessed at day 7, 14, 21 and ...28. Intra-articular drug ...
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