Intracellular survival
Phagocytosis influences the intracellular survival of Mycobacterium smegmatis via the endoplasmic reticulum stress response
... Mtb-generated ROS induce ER stress-mediated apop- tosis [28]. ROS lead to accumulation of misfolded pro- teins in the ER, which drives the ER stress response [29]. Therefore, we investigated the relationship between ROS ...
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Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular survival via treatment with methyl gallate alone and in combination with marbofloxacin
... In conclusion, in this study, we have reported the in vitro effects of MG in preventing bacterial adherence and entrance and intracellular survival in the host cells, either alone or in combination with ...
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The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis
... in intracellular survival of the world’s most successful bacterial pathogen, Mycobacterium tuberculosis ...the intracellular survival of ...PCK, intracellular Mtb requires PPDK as an ...
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Ehrlichia chaffeensis TRP120 Activates Canonical Notch Signaling To Downregulate TLR2/4 Expression and Promote Intracellular Survival
... However, the TRP effectors play important roles in immune sub- version by chromatin manipulation or by directly interacting with host proteins to modulate cellular processes. More recently, we demonstrated that TRP ...
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Immune Evasion, Stress Resistance, and Efficient Nutrient Acquisition Are Crucial for Intracellular Survival of Candida glabrata within Macrophages
... reduced intracellular replication may contribute to reduced ...reduced survival at 3 h postinfection may be explained by an extended time for the macrophages to apply their antimicrobial armamentarium or by ...
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SecA2 of Mycobacterium tuberculosis contributes to intracellular survival, immune modulation, and surface properties of the bacillus
... The second survival mechanism is the ability of M. tuberculosis to combat the toxic effects mediated by reactive nitrogen and reactive oxygen intermediates produced by the host cells. Enzymes that can detoxify ...
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Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants
... Phagocytosis is a key component of the innate immune response and of the clearance of apoptotic bodies. Phagosome formation and subsequent maturation require extensive cytoskeletal rear- rangement and precisely ...
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Th1 Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages
... Autophagy has been implicated in the adaptive immune response by playing a role in endogenous antigen presentation (Dengjel et al., 2005; Paludan et al., 2005). Autophagy is also involved in the innate response (Levine ...
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Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development
... in intracellular survival of NTHI following prior heme-iron restriction of the bacteria ...different intracellular localization pattern with significantly fewer colocalization events per cell ...
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Effects of Methylprednisolone on Intracellular Bacterial Growth
... the intracellular survival and replication of ...enhanced intracellular bacterial survival and replication, while stimulation with lower concen- trations of LPS ...terial survival and ...
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Occurrence of the invasion associated marker (iam) in Campylobacter jejuni isolated from cattle
... for intracellular survival in INT-407 as compared to ...and intracellular survival in the INT-407 cell line as compared to ...the intracellular survi- val potential in the human cell ...
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Acanthamoeba castellanii of the T4 genotype is a potential environmental host for Enterobacter aerogenes and Aeromonas hydrophila
... Next, to determine the number of intracellular bac- teria, invasion/uptake assays were performed. As per association, A. hydrophila exhibited higher invasion/up- take by A. castellanii (9.94 ± 0.98 bacteria:amoeba ...
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Glycogen synthesis correlates with androgen-dependent growth arrest in prostate cancer
... We showed that stimulation of glycogenesis, which exceeds glycogenolysis appeared to be responsible for the glycogen accumulation that inversely correlated with cell growth upon androgen-treatment in PC3-AR-V and PC3- ...
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Complete PHB mobilization in Escherichia coli enhances the stress tolerance: a potential biotechnological application
... mation provided the host with carbon and energy storage [2,28], while PHB mobilization is also of great impor- tance. Previous studies indicated that incomplete PHB mobilization system, like a phaZ mutant (lacking PHB ...
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HER4 expression in estrogen receptor positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women
... HER4 knockdown in ER-positive ZR-75-1 breast cancer cells resulted in about 90% reduced HER4 protein levels (Fig. 3a). Off-target effects on the other members of the HER receptor family (i.e., HER1, HER2, and HER3) could ...
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Intracellular pharmacodynamic modelling (PDi) is predictive of the clinical activity of fluoroquinolones against Tuberculosis
... Intracellular pharmacodynamic modelling (PDi) is predictive of the clinical activity of fluoroquinolones against Tuberculosis Intracellular pharmacodynamic modelling (PDi) is predictive of the clinica[.] ...
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Leaf extract of Caesalpinia mimosoides enhances oxidative stress resistance and prolongs lifespan in Caenorhabditis elegans
... In conclusion, the current study demonstrates the relevant antioxidant and anti-aging activities of the CM extract in C. elegans. The extract was able to increase stress resistance and to reduce intracellular ROS ...
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Effect of different intravenous iron preparations on lymphocyte intracellular reactive oxygen species generation and subpopulation survival
... increased intracellular ROS generation and reduced lymphocyte survival particularly of the CD4 + and CD16 + cell ...greater intracellular ROS generation, consistent with previous data regarding the ...
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Black_unc_0153D_15655.pdf
... how intracellular Ca2+ concentrations affect CIB1 ...by, intracellular Ca2+ release ...and intracellular Ca2+ has potentially significant functional ...in intracellular divalent cation ...
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Effects of zinc supplementation and zinc chelation on in vitro β cell function in INS 1E cells
... Unlike other zinc transporters, ZnT-5 holds a unique position in regulating intracellular Zn 2+ concentrations because it is localized in the Golgi apparatus, secretory vesicles, and in the cell membrane [63,64]. ...
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