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Intranasal Route

“Intranasal Route: A Putative Strategy for Novel Drug Delivery” by Asha Paul, Fathima K.M, Antony Nitheesh, Sreeja C Nair, India.

“Intranasal Route: A Putative Strategy for Novel Drug Delivery” by Asha Paul, Fathima K.M, Antony Nitheesh, Sreeja C Nair, India.

... Through intranasal route, first pass metabolism is avoided. The specialized anatomy and physiology of the nasal cavity and its ready accessibility make the nasal cavity a particularly attractive delivery ...

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 FORMULATION AND EVALUATION OF NOVEL BRAIN TARGETING DRUG LOADED IN LIPID-BASED NANOPARTICLES THROUGH INTRANASAL ROUTE FOR ALZHEIMER

 FORMULATION AND EVALUATION OF NOVEL BRAIN TARGETING DRUG LOADED IN LIPID-BASED NANOPARTICLES THROUGH INTRANASAL ROUTE FOR ALZHEIMER

... simulated intranasal fluid at pH ...simulated intranasal fluid at pH ...Simulated intranasal fluid at pH ...simulated intranasal fluid at pH ...

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Protective immunity induced by peptides of AMA1, RON2 and RON4 containing T and B cell epitopes via an intranasal route against toxoplasmosis in mice

Protective immunity induced by peptides of AMA1, RON2 and RON4 containing T and B cell epitopes via an intranasal route against toxoplasmosis in mice

... The intranasal immunization of mice with a single pep- tide (AMA1, RON2, RON4) or a mixture of peptides (A1 + R2, A1 + R4, R2 + R4 and A1 + R2 + R4) has been shown to induce effective mucosal and systemic immune ...

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The Optimization Design Of Lactoferrin Loaded HupA Nanoemulsion For Targeted Drug Transport Via Intranasal Route

<p>The Optimization Design Of Lactoferrin Loaded HupA Nanoemulsion For Targeted Drug Transport Via Intranasal Route</p>

... vivo, intranasal Lf-HupA-NE signi fi cantly enhanced drug delivery to the brain compared to HupA-NE, which was con fi rmed by differences in pharmaco- kinetic ...

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Induction of Mucosal Immune Response after Intranasal or Oral Inoculation of Mice with Lactococcus lactis Producing Bovine Beta-Lactoglobulin

Induction of Mucosal Immune Response after Intranasal or Oral Inoculation of Mice with Lactococcus lactis Producing Bovine Beta-Lactoglobulin

... After intranasal inoculation of a recombinant inducible strain expressing TTFC, an antigen-specific Ig serum response has been observed, but no antigen-specific fecal IgA was de- tected ...or intranasal ...

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Preparation, characterization, and in vivo evaluation of intranasally administered liposomal formulation of donepezil

Preparation, characterization, and in vivo evaluation of intranasally administered liposomal formulation of donepezil

... that intranasal administra- tion of liposomal formulation may improve the drug delivery to the ...by intranasal route in ...donepezil, intranasal, liposomes, bioavailability, blood–brain ...

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The Bacterial Second Messenger cdiGMP Exhibits Promising Activity as a Mucosal Adjuvant

The Bacterial Second Messenger cdiGMP Exhibits Promising Activity as a Mucosal Adjuvant

... subcutaneous route resulted in the stimu- lation of strong humoral and cellular immune responses, which were characterized by a balanced Th1/Th2 ...the intranasal route resulted in the stimulation of ...

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Identification of Wild-Derived Inbred Mouse Strains Highly Susceptible to Monkeypox Virus Infection for Use as Small Animal Models

Identification of Wild-Derived Inbred Mouse Strains Highly Susceptible to Monkeypox Virus Infection for Use as Small Animal Models

... an intranasal route of infection with an isolate of the Congo Basin clade of MPXV, CAST/EiJ mice exhibited weight loss, morbidity, and death in a dose-dependent manner with a calculated 50% lethal dose (LD ...

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Induction of Systemic and Mucosal Immune Responses to Human Immunodeficiency Virus Type 1 by a DNA Vaccine Formulated with QS-21 Saponin Adjuvant via Intramuscular and Intranasal Routes

Induction of Systemic and Mucosal Immune Responses to Human Immunodeficiency Virus Type 1 by a DNA Vaccine Formulated with QS-21 Saponin Adjuvant via Intramuscular and Intranasal Routes

... and intranasal immunizations with a DNA vaccine encoding env of HIV-1 and evaluated the QS-21 saponin adjuvant for augmentation of the systemic and mucosal immune responses to HIV-1 in a murine ...by ...

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Systemic Dissemination of H5N1 Influenza A Viruses in Ferrets and Hamsters after Direct Intragastric Inoculation

Systemic Dissemination of H5N1 Influenza A Viruses in Ferrets and Hamsters after Direct Intragastric Inoculation

... than intranasal viral ...gastric route, but not the intranasal route, showed interstitial lung lesions without bronchiolar epithelial lesions on micro- scopic examination ...

6

Comparison of Intranasal Midazolam with Oral Midazolam for Premedication in Children

Comparison of Intranasal Midazolam with Oral Midazolam for Premedication in Children

... of intranasal midazolam is similar to that when the drug is given intravenously and no significant complications have been reported when it is given by the intranasal ...

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IN  SITU NASAL GEL: MODERNISTIC ADVANCEMENT IN DRUG DELIVERY

IN SITU NASAL GEL: MODERNISTIC ADVANCEMENT IN DRUG DELIVERY

... the intranasal route of delivery can also provide a route of entry to the brain that circumvents the BBB, because the olfactory receptor cells are in direct contact with the CNS Recently, the nasal ...

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A Comparative Evaluation of Intranasal Dexmedetomidine and Intranasal Midazolam for Premedication in Children

A Comparative Evaluation of Intranasal Dexmedetomidine and Intranasal Midazolam for Premedication in Children

... of intranasal route are lace of pain, ease of use, avoidance of injection and rapid absorption of the drug directly into the systemic circulation from an area rich in blood supply without the disadvantage ...

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Case of Advanced Recurrent Glioblastoma Successfully Treated with Monoterpene Perillyl Alcohol by Intranasal Administration

Case of Advanced Recurrent Glioblastoma Successfully Treated with Monoterpene Perillyl Alcohol by Intranasal Administration

... by intranasal route four times a day (268 mg daily) as single chemotherapy ...that intranasal administration of the monoterpene POH as a single agent was an effective therapeutic strategy capable to ...

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AN OVERVIEW ON EXPLORING NASAL MICROEMULSION FOR TREATMENT OF CNS DISORDERS

AN OVERVIEW ON EXPLORING NASAL MICROEMULSION FOR TREATMENT OF CNS DISORDERS

... 6) Intranasal delivery of non peptides and peptides: Oral administration of peptides is impossible because of gastrointestinal enzymatic degradation and hepatic first-pass ...the intranasal route of ...

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Study of intranasal midazolam versus intranasal ketamine as a premedication in children undergoing surgical procedures

Study of intranasal midazolam versus intranasal ketamine as a premedication in children undergoing surgical procedures

... between intranasal midazolam and intranasal ketamine, using relevant parameters detailed above, was undertaken to determine which of the two drugs is better as a premedication in ...cases, intranasal ...

5

A RECENT REVIEW ON NASAL DRUG DELIVERY SYSTEM

A RECENT REVIEW ON NASAL DRUG DELIVERY SYSTEM

... alternative route of drug administration for local, systemic and central nervous system ...the intranasal route presents several limitations which must be overcome to develop a successful nasal ...

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Induction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles

Induction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles

... by intranasal delivery of a nanoparticle-based nasal vaccine against type A foot-and-mouth disease ...an intranasal route with nanoparticles and then challenged for 48 hours by direct contact with ...

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“VARIOUS METHODS OF DRUG TARGETING TO THE BRAIN: A REVIEW” by P. V. Pede*, S. S. Mitkare, R. S. Moon, India.

“VARIOUS METHODS OF DRUG TARGETING TO THE BRAIN: A REVIEW” by P. V. Pede*, S. S. Mitkare, R. S. Moon, India.

... invasive route including osmotic disruption, colloidal drug delivery, intranasal route of administration and nanotechnology have been proposed to favors brain drug ...appropriate route by ...

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NANOCARRIER FOR INTRANASAL ADMINISTRATION

NANOCARRIER FOR INTRANASAL ADMINISTRATION

... solution, intranasal conventional solution and intranasal nanoemulsio were assessed by comparison between Concentration vs AUC plots after administration of formulation ...Solution, intranasal spray ...

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