iron homeostasis
Multiple Evolutionarily Conserved Domains of Cap2 Are Required for Promoter Recruitment and Iron Homeostasis Gene Regulation
... Cap2 C-terminal region and the bZIP-HAP4L domains are essential for iron- responsive gene expression. Previous studies showed that deletion of CAP2 impaired the activation of ferric reductase gene FRP1 expression, ...
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The Role of NCOA4-Mediated Ferritinophagy in Iron Homeostasis
... repair[4,5]. Iron deficiency is the main cause of anemia[6], which causes significant morbidity and mortality ...when iron deficiency affects other tissues (skeletal muscle, heart or brain) it can have ...
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Deficiency of α-1-antitrypsin influences systemic iron homeostasis
... in iron homeostasis is by allowing an unrestricted activity of specific proteases which would result in increased iron ...of iron especially in the liver and spleen, which are major cites of ...
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Regulation of iron homeostasis by the hypoxia inducible transcription factors (HIFs)
... and iron metabolism, there are potential associations between the physiol- ogy of hypoxic response and the control of iron ...in iron homeostasis, we examined transcriptional control of the ...
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Molecular characterisation of genes involved in iron homeostasis.
... survival. Iron is a d-block transition element at 26 th position in periodic table exhibits various oxidation states ranging from -2 to ...system. Iron is an essential component for large number of proteins ...
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The Effects of Treatment on Serum Hepcidin and Iron Homeostasis in HIV 1 Infected In dividuals
... of iron in the body is regulated by complex mechanisms to maintain an appropriate amount of iron in the circulation and within tissues and avoid deficiency or overload ...human iron ...
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Regulation of tissue iron homeostasis: the macrophage “ferrostat”
... local iron homeostasis is important in AT for two major reasons: (i) iron availability is necessary for normal adipogenesis (121); and (ii) excess fatty acids in adipocytes, particu- larly in the ...
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The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans
... of iron uptake functions (15, ...to iron and ...of iron availability (29) ...to iron repletion in ...in iron regulation and virulence ...encoding iron use functions, as expected ...
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The Abnormal Measures of Iron Homeostasis in Pediatric Obesity Are Associated with the Inflammation of Obesity
... of iron deficiency among obese children, including consumption of high calorie, iron-poor diets, sedentary lifestyle resulting in decreased myoglobin breakdown, and increased iron requirements for ...
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Indices of iron homeostasis correlate with airway obstruction in an NHANES III cohort
... of iron homeo- stasis, serum C-reactive protein levels, and pulmonary function parameters reveal significant correlations among all in the study population, among smokers and among non- smokers (Tables ...of ...
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Evidence for a Role for Interleukin-17, Th17 Cells and Iron Homeostasis in Protective Immunity against Tuberculosis in Cynomolgus Macaques
... with iron homeostasis including ferritin heavy chain (FTH1), SLC11A1, transferrin receptor (TFRC), heme oxygenase 1 (HMOX1) and 5-aminolevulinate synthase, ery- throid-specific, mitochondrial (ALAS2) which ...
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MIR156 Participates in Iron Homeostasis Through Targeting SPL9/SPL15 in Arabidopsis Thaliana
... under iron deficiency. However, when grown under iron-deficiency, both 35S:miR156 and spl9/spl15 roots showed higher levels of ferric reduction rate when compared with WT ...ferric iron in the ...
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Iron Homeostasis in the Neonate
... Both iron deficiency and excess during the early weeks of life can have severe effects on neurodevelopment that may persist into adulthood and may not be corrected by restoration of normal iron ...their ...
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Characterizing Spatial Dynamics of Regulatory Mechanisms Involved in Plant Iron Homeostasis.
... to iron deprivation has been extensively studied in whole roots of wild-type, identifying novel genes involved in iron homeostasis (Dinneny et ...to iron deprivation, we conducted RNAseq ...
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Hepcidin, an emerging and important player in brain iron homeostasis
... to iron-load [7]. Iron-load induces production of bone mor- phogenetic protein 6 (BMP6) from LSECs, which then acts in neighbouring hepatocytes through BMP receptor (BMPR) [8] ...[5]. Iron-mediated ...
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Lipid induced changes in intracellular iron homeostasis in vitro and in vivo
... cellular iron storage depot, ferritin, acts as a critical antioxidant defense by sequestering unbound or "free" iron, limiting its participation in damaging oxidative ...free iron levels in ...
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Anemia and iron homeostasis in a cohort of HIV infected patients in Indonesia
... of iron parameters in a sub-group of patients revealed marked elevations in plasma ferritin, in line with earlier studies ...causes iron accumulation ...
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Psychological stress leads to hepatic iron accumulation and disturbs iron homeostasis
... for iron uptake into hepatocytes as transferrin-bound iron and NTBI have been well characterized [25 ， ...transferrin-bound iron, NTBI is more readily available for catalyzing free radical formation ...
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Hydrogen Sulphide Improves Iron Homeostasis in Wheat Under Iron-Deficiency
... Iron is one of the most important elements for plant growth, especially for chloroplast development, photosynthesis, respiration and DNA synthesis. Leaf yellowing is a typical phenotype caused by Fe-deficiency and ...
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Ghio_2018_J._Breath_Res._12_046009.pdf
... decreased iron concentra- tions in the ELF ( ...of iron among patients with COPD; methodology employed to measure iron in this study used a bleomycin assay which reflects pro-oxidant levels rather ...
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