JUVENILE-ONSET
Evidence of Small-Fiber Polyneuropathy in Unexplained, Juvenile-Onset, Widespread Pain Syndromes
... preliminary evidence of disordered immunity in some patients, including hypocomplementemia among other serologic abnormalities, and respon- siveness to corticosteroid and immu- noglobulin therapy in some patients. ...
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Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations
... of juvenile-onset disease may be linked to the gradual expansion of mite populations (Forton 2011, Ravera et ...because juvenile-onset of the disease is generally attributed to a genetic ...
10
Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature
... Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American College of ...
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Investigating the role of Toll-like receptors in juvenile onset systemic lupus erythematosus
... [39]. Onset occurs prior to the age of 18, typically between 12-16 years although children can be diagnosed at a much earlier age, and accounts for up to 20% of all cases of SLE [40- ...
116
Successful implementation of a clinical transition pathway for adolescents with juvenile-onset rheumatic and musculoskeletal diseases
... with juvenile-onset rheumatic and musculoskeletal diseases (jRMD) need to be prepared well in advance, to achieve a successful transfer to adult rheumatology care ...
8
The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus
... damage. Juvenile-onset SLE (JSLE) is less common than adult onset disease affec- ting between 6 and 30 people per 100,000 depending on ethic group ...
6
Sex differences in metabolic and adipose tissue responses to juvenile onset obesity in sheep
... mass in females, which can lead to in- sulin resistance (30). The exact mech- anism behind a sex hormone-medi- ated retardation in the rate of development of insulin resistance in obesity observed in females is cur- ...
10
Renal biomarkers in Juvenile-onset systemic lupus erythematosus
... Childhood-onset SLE is associated with a more active disease course and preponderance for LN. LN is difficult to diagnose clinically as current markers occur later in the disease process, during which time ...
377
Brain structure in juvenile-onset Huntington disease
... disease onset and including the motor ...and onset before age 10), there was selective and severe degeneration of the striatum with sparing of the cerebral white matter and ...
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Assessment of the Performance of a Modified Motor Scale as Applied to Juvenile Onset Huntington’s Disease
... of onset was not collected systematically as data were collected separately from the main REGISTRY data, so we were not able to stratify the results into those with onset ≤10 years from those with ...
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Long-Term Outcomes of Adolescents With Juvenile-Onset Fibromyalgia in Early Adulthood
... The current study is the largest pro- spective longitudinal study of JFM patients to date, allowing for the fi rst time an in-depth understanding of physical, psychological, and social/ vocational outcomes in young adult- ...
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An unusual splicing mutation in the HEXB gene is associated with dramatically different phenotypes in patients from different racial backgrounds
... Sandhoff disease is caused by mutations affecting the beta subunit of lysosomal beta- hexosaminidase (EC 3.2.1.52) and displays a wide spectrum of clinical phenotypes. We report a 57-year-old patient with a very mild ...
10
Application of the Yamaguchi criteria for classification of “suspected” systemic juvenile idiopathic arthritis (sJIA)
... Data pertaining to the delay in (or absence of ) arthritic manifestations of sJIA is scarce. A cohort of 46 patients with “probable” Still’s disease (as defined by the Taplow group criteria) was published in 1962. These ...
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Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult
... after onset, the level of transgene expression in dox-reared animals is not identical to ...of juvenile-onset mice, it starts off approximately 25% ...than juvenile-onset ani- mals ...
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Hyponatremia, Hypophosphatemia, and Hypouricemia in a Girl With Macrophage Activation Syndrome
... systemic-onset juvenile arthritis [SOJA]), is character- ized by persistent fever, pancytopenia, lymphadenopa- thy, hepatosplenomegaly, elevated serum liver enzyme levels, and coagulation ...
6
Treatment of systemic-onset juvenile arthritis with canakinumab
... to onset of a disease relapse was 236 days (95% confidence interval 141–449) in the placebo cohort and was not determinable for canakinumab, since less than 50% of the patients ever had a ...
9
Periocular xanthogranuloma: A forgotten entity?
... Abstract: Periocular xanthogranulomatous diseases are a rare group of disorders which are characterized by a predilection to affect the orbit and ocular adnexa and special histo- pathological features, in particular ...
6
Ekta Singh Chauhan*, Shivani Srivastava and Akriti Singh
... Delayed puberty onset in rats that consumed aqueous extract of Hibiscus sabdariffa during the juvenile-pubertal period. Polyphenols extracted from Hibiscus sabdariffa [r] ...
6
Hemophagocytic lymphohistiocytosis with leukoencephalopathy in a patient with dermatomyositis accompanied with peripheral T cell lymphoma: a case report
... CNS involvement is commonly seen in patients with hereditary HLH [11]. However, CNS involvement is less commonly seen in patients with autoimmune-associated HLH than in patients with malignancy-associated and viral ...
7
Significance of the parkin and PINK1gene in Jordanian families with incidences of young-onset and juvenile parkinsonism
... at onset amongst putative parkin and PINK1 mutation carri- ers as compared to non-carriers (Table ...at onset within affected of the same ...at onset was seen in both affected, as com- pared to ...
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