Kainate Receptors
Cortical kainate receptors and behavioral anxiety
... KA receptors have been reported in many central synapses, the contribution of KA receptors to baseline synaptic transmission is highly ...KA receptors in nocicep- tive transmission in the spinal cord ...
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Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice
... (FMRP). Kainate receptor (KAR) is a subfamily of ionotropic glutamate receptors (iGluR) that acts mainly as a neuromodulator of synaptic transmission and neuronal ...
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Glutamate as a Neural Stress Factor in Humans and Animals
... and kainate receptors (ligand gated calcium channels) and III groups of the metabotropic glutamate receptors (mGluR 1-8 ) family members (G-protein coupled ...
13
N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis
... (AMPA), kainate, and N-methyl-D-aspartate receptors ...and kainate receptors, in- cluding voltage-sensitive blockade by Mg 2+ , high perme- ability to Ca 2+ , requirement of glycine as a ...
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Genome wide identification, characterization and classification of ionotropic glutamate receptor genes (iGluRs) in the malaria vector Anopheles sinensis (Diptera: Culicidae)
... pionate) receptors, Kainate receptors and NMDA (N-me- thyl-D-aspartate) receptors, ...and Kainate receptors are further grouped to- gether as non-NMDA ...AMPA receptors ...
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Intracellular Ca2+ release mediated by metabotropic glutamate receptor activation in the leech giant glial cell
... (AMPA)/kainate receptors by reference to their artificial agonists (Nakanishi, 1992; Watkins et ...glutamate receptors (mGluRs) are coupled to GTP-binding proteins (G-proteins) with a broad spectrum ...
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Nimesulide limits kainate-induced oxidative damage in the rat hippocampus
... of kainate toxicity support the hypothesis that the main cause of neurotoxicity is the activation of presynaptic kainate receptors and the release of endogenous glutamate (Ferkany et ...glutamate ...
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Cerebellar cortical AMPA/kainate receptor blockade prevents performance of classically conditioned nictitating membrane responses
... Classical conditioning of the nictitating membrane–eye blink response of rabbits is a simple form of associative motor learning. Lesion studies have shown that performance of learned responses is dependent on the ...
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A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia
... AMPA/ kainate receptors in Adar2 +/− mice was characterized by preserved Q/R site editing of Gria2 and decreased edit- ing of R/G ...AMPA receptors and Htr2c ...
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Regulation of Ion Channel and Transporter Function Through RNA Editing
... 764, receptors recover from desensitization twice as ...when receptors were activated by physiologically relevant applications of glutamate in terms of concentration and duration, suggesting that this edit ...
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Importance of innate mucosal immunity and the promises it holds
... Pyrin domain-containing NOD-like receptors play a key role in the regulation of caspase-1 by forming a multiprotein complex known as the “inflammasome”. Caspase-1 partici- pates in the processing and subsequent ...
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Biochemical and anatomical correlates of cortical pyramidal neurones- Implications for the treatment of Alzheimer's disease
... acetylcholine receptors have been categorised in two classes: muscle type and neuronal ...nicotinic receptors (Loring and Zigmond, 1988). N euronal nicotinic receptors are widely distributed ...
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Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity
... A series of events initiated by glutamate-receptor interaction perturbs cellular homeostasis resulting in elevation of intracellular free calcium and cell death. Cells subject to such environmental change express stress ...
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Liver X receptor opens a new gateway to StAR and to steroid hormones
... Liver X receptors (LXRs) broadly limit cholesterol accumulation by regu- lating expression of genes involved in cholesterol efflux and storage. In this issue of the JCI, Cummins et al. report that LXRα is involved ...
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(R)-[11C]Verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus
... The aim of this study was to investigate potential changes in P-gp expression and functionality in vivo with positron emission tomography (PET). For this purpose a condition at which there is clear increased P-gp ...
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Fabrication and use of D serine biosensors for characterising D serine signalling in rat brain
... Significant levels of D-serine were localised to the brain in the 1990s showing D- serine distribution paralleled that of NMDA receptors (Hashimoto et al., 1993a; Schell et al., 1995; Schell et al., 1997). Over ...
185
Expression of HIV receptors, alternate receptors and co receptors on tonsillar epithelium: implications for HIV binding and primary oral infection
... Expression of HIV co-receptors CXCR4 and CCR5 Several previous studies have reported expression of the principal HIV co-receptors, CXCR4 and CCR5, on cul- tured epithelial cells [32,48,49] and that oral ...
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Identification and Expression Analysis of Putative Chemosensory Receptor Genes in Microplitis mediator by Antennal Transcriptome Screening
... In the present study, we focused on three crucial families of chemosensory receptor (ORs, GRs and IRs) due to their significance as potential target genes for manipulating parasitoid wasps in order to improve biological ...
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Pharmacology of ionotropic and metabotropic glutamate receptors on neurons involved in feeding behavior in the pond snail, Helisoma trivolvis
... the receptors that mediate this regulation are only partially ...glutamate receptors on three buccal neurons modulated by ...–1 kainate (KA), suggesting ...
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Curcumin: The Molecular Mechanisms of Action in Inflammation and Cell Death during Kainate-Induced Epileptogenesis
... expression of NCSTN was likely attributed to neuronal cell loss induced by KA. However, there is very little known about the role of nicastrin in epileptogenesis. In contrast to KA treatment, NCSTN gene was over- ...
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